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Items: 1 to 20 of 126

1.

Ku80 facilitates chromatin binding of the telomere binding protein, TRF2.

Fink LS, Lerner CA, Torres PF, Sell C.

Cell Cycle. 2010 Sep 15;9(18):3798-806. Epub 2010 Sep 25.

2.

TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres.

Ribes-Zamora A, Indiviglio SM, Mihalek I, Williams CL, Bertuch AA.

Cell Rep. 2013 Oct 17;5(1):194-206. doi: 10.1016/j.celrep.2013.08.040. Epub 2013 Oct 3.

3.

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination.

Celli GB, Denchi EL, de Lange T.

Nat Cell Biol. 2006 Aug;8(8):885-90. Epub 2006 Jul 16.

PMID:
16845382
4.

No overt nucleosome eviction at deprotected telomeres.

Wu P, de Lange T.

Mol Cell Biol. 2008 Sep;28(18):5724-35. doi: 10.1128/MCB.01764-07. Epub 2008 Jul 14.

5.

Suppression of Ku80 correlates with radiosensitivity and telomere shortening in the U2OS telomerase-negative osteosarcoma cell line.

Hu L, Wu QQ, Wang WB, Jiang HG, Yang L, Liu Y, Yu HJ, Xie CH, Zhou YF, Zhou FX.

Asian Pac J Cancer Prev. 2013;14(2):795-9.

6.

Interaction of human Ku70 with TRF2.

Song K, Jung D, Jung Y, Lee SG, Lee I.

FEBS Lett. 2000 Sep 8;481(1):81-5.

7.

KARP-1 works as a heterodimer with Ku70, but the function of KARP-1 cannot perfectly replace that of Ku80 in DSB repair.

Koike M, Yutoku Y, Koike A.

Exp Cell Res. 2011 Oct 1;317(16):2267-75. doi: 10.1016/j.yexcr.2011.06.015. Epub 2011 Jul 2.

PMID:
21756904
8.
9.

Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer.

Hu H, Zhang Y, Zou M, Yang S, Liang XQ.

J Cancer Res Clin Oncol. 2010 Sep;136(9):1407-14. doi: 10.1007/s00432-010-0795-x. Epub 2010 Feb 2.

PMID:
20127252
10.

One ring to bring them all--the role of Ku in mammalian non-homologous end joining.

Grundy GJ, Moulding HA, Caldecott KW, Rulten SL.

DNA Repair (Amst). 2014 May;17:30-8. doi: 10.1016/j.dnarep.2014.02.019. Epub 2014 Mar 26. Review.

PMID:
24680220
11.

Removal of shelterin reveals the telomere end-protection problem.

Sfeir A, de Lange T.

Science. 2012 May 4;336(6081):593-7. doi: 10.1126/science.1218498.

12.

Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions.

Ribes-Zamora A, Mihalek I, Lichtarge O, Bertuch AA.

Nat Struct Mol Biol. 2007 Apr;14(4):301-7. Epub 2007 Mar 11.

PMID:
17351632
13.

Changes in the expression of telomere maintenance genes might play a role in the pathogenesis of systemic lupus erythematosus.

Zhou JG, Qing YF, Yang QB, Xie WG, Zhao MC.

Lupus. 2011 Jul;20(8):820-8. doi: 10.1177/0961203310397964.

PMID:
21693493
14.

The Ku heterodimer: function in DNA repair and beyond.

Fell VL, Schild-Poulter C.

Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:15-29. doi: 10.1016/j.mrrev.2014.06.002. Epub 2014 Jul 4. Review.

PMID:
25795113
15.

An SCF complex containing Fbxl12 mediates DNA damage-induced Ku80 ubiquitylation.

Postow L, Funabiki H.

Cell Cycle. 2013 Feb 15;12(4):587-95. doi: 10.4161/cc.23408. Epub 2013 Jan 16.

16.

Nucleolar localization of the human telomeric repeat binding factor 2 (TRF2).

Zhang S, Hemmerich P, Grosse F.

J Cell Sci. 2004 Aug 1;117(Pt 17):3935-45. Epub 2004 Jul 20.

17.

Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast.

Miyoshi T, Sadaie M, Kanoh J, Ishikawa F.

J Biol Chem. 2003 Jan 17;278(3):1924-31. Epub 2002 Nov 6.

18.

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.

Celli GB, de Lange T.

Nat Cell Biol. 2005 Jul;7(7):712-8. Epub 2005 Jun 19.

PMID:
15968270
20.

The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine.

Zhang YW, Zhang ZX, Miao ZH, Ding J.

Mol Pharmacol. 2008 Mar;73(3):824-32. Epub 2007 Nov 19. Erratum in: Mol Pharmacol. 2008 May;73(5):1587.

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