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Items: 1 to 20 of 151


Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress.

Tollefson AK, Oberley-Deegan RE, Butterfield KT, Nicks ME, Weaver MR, Remigio LK, Decsesznak J, Chu HW, Bratton DL, Riches DW, Bowler RP.

Free Radic Biol Med. 2010 Dec 15;49(12):1937-46. doi: 10.1016/j.freeradbiomed.2010.09.022. Epub 2010 Sep 29.


Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation.

Thatcher TH, Hsiao HM, Pinner E, Laudon M, Pollock SJ, Sime PJ, Phipps RP.

Am J Physiol Lung Cell Mol Physiol. 2013 Jul 15;305(2):L165-74. doi: 10.1152/ajplung.00036.2013. Epub 2013 May 17.


Anti-malarial drug artesunate protects against cigarette smoke-induced lung injury in mice.

Ng DS, Liao W, Tan WS, Chan TK, Loh XY, Wong WS.

Phytomedicine. 2014 Oct 15;21(12):1638-44. doi: 10.1016/j.phymed.2014.07.018. Epub 2014 Sep 1.


Vitamin E isoform γ-tocotrienol protects against emphysema in cigarette smoke-induced COPD.

Peh HY, Tan WSD, Chan TK, Pow CW, Foster PS, Wong WSF.

Free Radic Biol Med. 2017 Sep;110:332-344. doi: 10.1016/j.freeradbiomed.2017.06.023. Epub 2017 Jul 3.


Bilirubin treatment suppresses pulmonary inflammation in a rat model of smoke-induced emphysema.

Wei J, Zhao H, Fan G, Li J.

Biochem Biophys Res Commun. 2015 Sep 18;465(2):180-7. doi: 10.1016/j.bbrc.2015.07.133. Epub 2015 Jul 30.


Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM.

Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15571-6. doi: 10.1073/pnas.1007625107. Epub 2010 Aug 16.


Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca²⁺.

Lin AH, Liu MH, Ko HK, Perng DW, Lee TS, Kou YR.

Mediators Inflamm. 2015;2015:148367. doi: 10.1155/2015/148367. Epub 2015 Oct 4.


Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice.

Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.

J Pharmacol Exp Ther. 2008 May;325(2):380-8. doi: 10.1124/jpet.107.134007. Epub 2008 Feb 6.


Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process.

Geraghty P, Wallace A, D'Armiento JM.

Int J Chron Obstruct Pulmon Dis. 2011;6:309-19. doi: 10.2147/COPD.S19599. Epub 2011 Jun 2.


The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1.

Sarill M, Zago M, Sheridan JA, Nair P, Matthews J, Gomez A, Roussel L, Rousseau S, Hamid Q, Eidelman DH, Baglole CJ.

Free Radic Biol Med. 2015 Dec;89:342-57. doi: 10.1016/j.freeradbiomed.2015.08.007. Epub 2015 Sep 25.


Aerobic exercise attenuates pulmonary injury induced by exposure to cigarette smoke.

Toledo AC, Magalhaes RM, Hizume DC, Vieira RP, Biselli PJ, Moriya HT, Mauad T, Lopes FD, Martins MA.

Eur Respir J. 2012 Feb;39(2):254-64. doi: 10.1183/09031936.00003411. Epub 2011 Jun 23.


Protective effects of liquiritin apioside on cigarette smoke-induced lung epithelial cell injury.

Guan Y, Li FF, Hong L, Yan XF, Tan GL, He JS, Dong XW, Bao MJ, Xie QM.

Fundam Clin Pharmacol. 2012 Aug;26(4):473-83. doi: 10.1111/j.1472-8206.2011.00956.x. Epub 2011 Jun 1.


The administration of a high refined carbohydrate diet promoted an increase in pulmonary inflammation and oxidative stress in mice exposed to cigarette smoke.

Pena KB, Ramos CO, Soares NP, da Silva PF, Bandeira AC, Costa GP, Cangussú SD, Talvani A, Bezerra FS.

Int J Chron Obstruct Pulmon Dis. 2016 Dec 15;11:3207-3217. doi: 10.2147/COPD.S119485. eCollection 2016.


Extracellular superoxide dismutase and risk of COPD.

Oberley-Deegan RE, Regan EA, Kinnula VL, Crapo JD.

COPD. 2009 Aug;6(4):307-12. Review.


NADPH oxidase (NOX) 1 mediates cigarette smoke-induced superoxide generation in rat vascular smooth muscle cells.

Chang KH, Park JM, Lee CH, Kim B, Choi KC, Choi SJ, Lee K, Lee MY.

Toxicol In Vitro. 2017 Feb;38:49-58. doi: 10.1016/j.tiv.2016.10.013. Epub 2016 Nov 3.


Cigarette smoke extract affects mitochondrial function in alveolar epithelial cells.

Ballweg K, Mutze K, Königshoff M, Eickelberg O, Meiners S.

Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L895-907. doi: 10.1152/ajplung.00180.2014. Epub 2014 Oct 17.


SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.

Yao H, Sundar IK, Ahmad T, Lerner C, Gerloff J, Friedman AE, Phipps RP, Sime PJ, McBurney MW, Guarente L, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L816-28. doi: 10.1152/ajplung.00323.2013. Epub 2014 Mar 14.


Oxidative stress is an important component of airway inflammation in mice exposed to cigarette smoke or lipopolysaccharide.

Lagente V, Planquois JM, Leclerc O, Schmidlin F, Bertrand CP.

Clin Exp Pharmacol Physiol. 2008 May;35(5-6):601-5. doi: 10.1111/j.1440-1681.2007.04848.x. Epub 2007 Dec 27.


Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity.

Guan SP, Tee W, Ng DS, Chan TK, Peh HY, Ho WE, Cheng C, Mak JC, Wong WS.

Br J Pharmacol. 2013 Apr;168(7):1707-18. doi: 10.1111/bph.12054.

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