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Items: 1 to 20 of 84

1.

Hypoxia triggers major metabolic changes in AML cells without altering indomethacin-induced TCA cycle deregulation.

Lodi A, Tiziani S, Khanim FL, Drayson MT, Günther UL, Bunce CM, Viant MR.

ACS Chem Biol. 2011 Feb 18;6(2):169-75. doi: 10.1021/cb900300j. Epub 2010 Oct 18.

2.

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.

Birtwistle J, Hayden RE, Khanim FL, Green RM, Pearce C, Davies NJ, Wake N, Schrewe H, Ride JP, Chipman JK, Bunce CM.

Mutat Res. 2009 Mar 9;662(1-2):67-74. doi: 10.1016/j.mrfmmm.2008.12.010. Epub 2008 Dec 31.

PMID:
19162045
3.

Importance of glutamine metabolism in leukemia cells by energy production through TCA cycle and by redox homeostasis.

Goto M, Miwa H, Shikami M, Tsunekawa-Imai N, Suganuma K, Mizuno S, Takahashi M, Mizutani M, Hanamura I, Nitta M.

Cancer Invest. 2014 Jul;32(6):241-7. doi: 10.3109/07357907.2014.907419. Epub 2014 Apr 24.

PMID:
24762082
4.
5.
6.

Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress.

Goto M, Miwa H, Suganuma K, Tsunekawa-Imai N, Shikami M, Mizutani M, Mizuno S, Hanamura I, Nitta M.

BMC Cancer. 2014 Feb 10;14:76. doi: 10.1186/1471-2407-14-76.

7.

Tryptamine-gallic acid hybrid prevents non-steroidal anti-inflammatory drug-induced gastropathy: correction of mitochondrial dysfunction and inhibition of apoptosis in gastric mucosal cells.

Pal C, Bindu S, Dey S, Alam A, Goyal M, Iqbal MS, Sarkar S, Kumar R, Halder KK, Debnath MC, Adhikari S, Bandyopadhyay U.

J Biol Chem. 2012 Jan 27;287(5):3495-509. doi: 10.1074/jbc.M111.307199. Epub 2011 Dec 7.

8.

Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose.

Miwa H, Shikami M, Goto M, Mizuno S, Takahashi M, Tsunekawa-Imai N, Ishikawa T, Mizutani M, Horio T, Gotou M, Yamamoto H, Wakabayashi M, Watarai M, Hanamura I, Imamura A, Mihara H, Nitta M.

Oncol Rep. 2013 May;29(5):2053-7. doi: 10.3892/or.2013.2299. Epub 2013 Feb 21.

PMID:
23440281
9.

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.

Jacque N, Ronchetti AM, Larrue C, Meunier G, Birsen R, Willems L, Saland E, Decroocq J, Maciel TT, Lambert M, Poulain L, Hospital MA, Sujobert P, Joseph L, Chapuis N, Lacombe C, Moura IC, Demo S, Sarry JE, Recher C, Mayeux P, Tamburini J, Bouscary D.

Blood. 2015 Sep 10;126(11):1346-56. doi: 10.1182/blood-2015-01-621870. Epub 2015 Jul 17.

10.

Cell metabolism under microenvironmental low oxygen tension levels in stemness, proliferation and pluripotency.

De Miguel MP, Alcaina Y, de la Maza DS, Lopez-Iglesias P.

Curr Mol Med. 2015;15(4):343-59.

PMID:
25941818
11.

Metabolic adaptation to chronic inhibition of mitochondrial protein synthesis in acute myeloid leukemia cells.

Jhas B, Sriskanthadevan S, Skrtic M, Sukhai MA, Voisin V, Jitkova Y, Gronda M, Hurren R, Laister RC, Bader GD, Minden MD, Schimmer AD.

PLoS One. 2013;8(3):e58367. doi: 10.1371/journal.pone.0058367. Epub 2013 Mar 8.

12.

Hypoxia and the metabolic phenotype of prostate cancer cells.

Higgins LH, Withers HG, Garbens A, Love HD, Magnoni L, Hayward SW, Moyes CD.

Biochim Biophys Acta. 2009 Dec;1787(12):1433-43. doi: 10.1016/j.bbabio.2009.06.003. Epub 2009 Jun 12.

13.

Analysis of hypoxia-induced metabolic reprogramming.

Yang C, Jiang L, Zhang H, Shimoda LA, DeBerardinis RJ, Semenza GL.

Methods Enzymol. 2014;542:425-55. doi: 10.1016/B978-0-12-416618-9.00022-4. Review.

PMID:
24862279
14.

Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines.

Tiziani S, Lodi A, Khanim FL, Viant MR, Bunce CM, Günther UL.

PLoS One. 2009;4(1):e4251. doi: 10.1371/journal.pone.0004251. Epub 2009 Jan 22. Erratum in: PLoS One. 2009;4(4). doi: 10.1371/annotation/39584d38-04f5-4b37-bfd8-eae2318ec6f9.

15.

Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells.

Filipp FV, Scott DA, Ronai ZA, Osterman AL, Smith JW.

Pigment Cell Melanoma Res. 2012 May;25(3):375-83. doi: 10.1111/j.1755-148X.2012.00989.x. Epub 2012 Mar 27.

16.
17.

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells.

Janzer A, German NJ, Gonzalez-Herrera KN, Asara JM, Haigis MC, Struhl K.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10574-9. doi: 10.1073/pnas.1409844111. Epub 2014 Jul 7.

18.
19.

Phospholipid profiles of invasive human breast cancer cells are altered towards a less invasive phospholipid profile by the anti-inflammatory agent indomethacin.

Natarajan K, Mori N, Artemov D, Aboagye EO, Chacko VP, Bhujwalla ZM.

Adv Enzyme Regul. 2000;40:271-84. No abstract available.

PMID:
10828355
20.

Metabolic changes in the glucose-induced apoptotic blastocyst suggest alterations in mitochondrial physiology.

Chi MM, Hoehn A, Moley KH.

Am J Physiol Endocrinol Metab. 2002 Aug;283(2):E226-32.

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