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Items: 1 to 20 of 64

1.

Proteomic analysis reveals a novel mechanism induced by the leukemic oncogene Tel/PDGFRβ in stem cells: activation of the interferon response pathways.

Dobbin E, Graham C, Freeburn RW, Unwin RD, Griffiths JR, Pierce A, Whetton AD, Wheadon H.

Stem Cell Res. 2010 Nov;5(3):226-43. doi: 10.1016/j.scr.2010.08.001.

2.

Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways.

Dobbin E, Graham C, Corrigan PM, Thomas KG, Freeburn RW, Wheadon H.

Exp Hematol. 2009 Jan;37(1):111-121. doi: 10.1016/j.exphem.2008.09.012.

PMID:
19100521
4.

Gamma interferon triggers interaction between ICSBP (IRF-8) and TEL, recruiting the histone deacetylase HDAC3 to the interferon-responsive element.

Kuwata T, Gongora C, Kanno Y, Sakaguchi K, Tamura T, Kanno T, Basrur V, Martinez R, Appella E, Golub T, Ozato K.

Mol Cell Biol. 2002 Nov;22(21):7439-48.

5.
6.

The Tel-PDGFRbeta fusion gene produces a chronic myeloproliferative syndrome in transgenic mice.

Ritchie KA, Aprikyan AA, Bowen-Pope DF, Norby-Slycord CJ, Conyers S, Bartelmez S, Sitnicka EH, Hickstein DD.

Leukemia. 1999 Nov;13(11):1790-803.

PMID:
10557054
7.

Tel/PDGFRbeta inhibits self-renewal and directs myelomonocytic differentiation of ES cells.

Dobbin E, Corrigan PM, Walsh CP, Welham MJ, Freeburn RW, Wheadon H.

Leuk Res. 2008 Oct;32(10):1554-64. doi: 10.1016/j.leukres.2008.02.007.

PMID:
18355917
8.

Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage.

Cain JA, Xiang Z, O'Neal J, Kreisel F, Colson A, Luo H, Hennighausen L, Tomasson MH.

Blood. 2007 May 1;109(9):3906-14.

9.

Functional correction of FA-C cells with FANCC suppresses the expression of interferon gamma-inducible genes.

Fagerlie SR, Diaz J, Christianson TA, McCartan K, Keeble W, Faulkner GR, Bagby GC.

Blood. 2001 May 15;97(10):3017-24.

10.

IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNgamma-responsive promoters in macrophages.

Contursi C, Wang IM, Gabriele L, Gadina M, O'Shea J, Morse HC 3rd, Ozato K.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):91-6.

11.

TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins.

Wilbanks AM, Mahajan S, Frank DA, Druker BJ, Gilliland DG, Carroll M.

Exp Hematol. 2000 May;28(5):584-93.

PMID:
10812249
12.

Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription.

Huang W, Zhou W, Saberwal G, Konieczna I, Horvath E, Katsoulidis E, Platanias LC, Eklund EA.

Mol Cell Biol. 2010 Oct;30(19):4575-94. doi: 10.1128/MCB.01595-09.

13.
15.

Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors.

Egwuagu CE, Li W, Yu CR, Che Mei Lin M, Chan CC, Nakamura T, Chepelinsky AB.

Oncogene. 2006 Jun 22;25(26):3670-9.

PMID:
16462767
16.

Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.

Medves S, Noël LA, Montano-Almendras CP, Albu RI, Schoemans H, Constantinescu SN, Demoulin JB.

Haematologica. 2011 Oct;96(10):1406-14. doi: 10.3324/haematol.2011.040147.

17.
19.

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis.

Wheadon H, Ramsey JM, Dobbin E, Dickson GJ, Corrigan PM, Freeburn RW, Thompson A.

Stem Cells Dev. 2011 Aug;20(8):1465-76. doi: 10.1089/scd.2010.0226.

PMID:
21083428
20.

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein.

Jousset C, Carron C, Boureux A, Quang CT, Oury C, Dusanter-Fourt I, Charon M, Levin J, Bernard O, Ghysdael J.

EMBO J. 1997 Jan 2;16(1):69-82.

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