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Items: 1 to 20 of 113

1.

Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility.

Mosbaek CR, Nolan D, Persson E, Svergun DI, Bukrinsky JT, Vestergaard B.

Biochemistry. 2010 Nov 16;49(45):9739-45. doi: 10.1021/bi1011207. Epub 2010 Oct 20.

PMID:
20873866
3.

The tissue factor/factor VIIa/factor Xa complex: a model built by docking and site-directed mutagenesis.

Norledge BV, Petrovan RJ, Ruf W, Olson AJ.

Proteins. 2003 Nov 15;53(3):640-8.

PMID:
14579355
4.
5.

The origins of enhanced activity in factor VIIa analogs and the interplay between key allosteric sites revealed by hydrogen exchange mass spectrometry.

Rand KD, Andersen MD, Olsen OH, Jørgensen TJ, Ostergaard H, Jensen ON, Stennicke HR, Persson E.

J Biol Chem. 2008 May 9;283(19):13378-87. doi: 10.1074/jbc.M709716200. Epub 2008 Mar 14.

6.

Inhibitors of Tissue Factor. Factor VIIa for anticoagulant therapy.

Lazarus RA, Olivero AG, Eigenbrot C, Kirchhofer D.

Curr Med Chem. 2004 Sep;11(17):2275-90. Review.

PMID:
15379712
7.

Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa.

Persson E, Olsen OH.

FEBS J. 2009 Jun;276(11):3099-109. doi: 10.1111/j.1742-4658.2009.07028.x. Epub 2009 Apr 23.

8.
9.
10.

Allosteric activation of coagulation factor VIIa.

Persson E, Olsen OH.

Front Biosci (Landmark Ed). 2011 Jun 1;16:3156-63. Review.

PMID:
21622226
11.

Predicted solution structure of zymogen human coagulation FVII.

Perera L, Darden TA, Pedersen LG.

J Comput Chem. 2002 Jan 15;23(1):35-47.

PMID:
11913388
12.

Allosteric activation of coagulation factor VIIa visualized by hydrogen exchange.

Rand KD, Jørgensen TJ, Olsen OH, Persson E, Jensen ON, Stennicke HR, Andersen MD.

J Biol Chem. 2006 Aug 11;281(32):23018-24. Epub 2006 May 10.

13.

Modulators of the coagulation cascade: focus and recent advances in inhibitors of tissue factor, factor VIIa and their complex.

Frédérick R, Pochet L, Charlier C, Masereel B.

Curr Med Chem. 2005;12(4):397-417. Review.

PMID:
15720249
14.

Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity.

Persson E, Kjalke M, Olsen OH.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13583-8. Epub 2001 Nov 6.

16.

Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla).

Kemball-Cook G, Johnson DJ, Tuddenham EG, Harlos K.

J Struct Biol. 1999 Oct;127(3):213-23.

PMID:
10544046
18.

Sequential coagulation factor VIIa domain binding to tissue factor.

Osterlund M, Persson E, Carlsson U, Freskgård PO, Svensson M.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1276-82. Epub 2005 Oct 10.

PMID:
16236263
19.
20.

Tissue factor alters the pK(a) values of catalytically important factor VIIa residues.

Neuenschwander PF, Vernon JT, Morrissey JH.

Biochemistry. 2002 Mar 12;41(10):3364-71.

PMID:
11876644

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