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Items: 1 to 20 of 90

1.

Targeted disruption of the porcine immunoglobulin kappa light chain locus.

Ramsoondar J, Mendicino M, Phelps C, Vaught T, Ball S, Monahan J, Chen S, Dandro A, Boone J, Jobst P, Vance A, Wertz N, Polejaeva I, Butler J, Dai Y, Ayares D, Wells K.

Transgenic Res. 2011 Jun;20(3):643-53. doi: 10.1007/s11248-010-9445-y. Epub 2010 Sep 26.

PMID:
20872247
2.

Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus.

Mendicino M, Ramsoondar J, Phelps C, Vaught T, Ball S, LeRoith T, Monahan J, Chen S, Dandro A, Boone J, Jobst P, Vance A, Wertz N, Bergman Z, Sun XZ, Polejaeva I, Butler J, Dai Y, Ayares D, Wells K.

Transgenic Res. 2011 Jun;20(3):625-41. doi: 10.1007/s11248-010-9444-z. Epub 2010 Sep 26.

PMID:
20872248
3.
5.

Generation of chimeric monoclonal antibodies from mice that carry human immunoglobulin Cgamma1 heavy of Ckappa light chain gene segments.

Pluschke G, Joss A, Marfurt J, Daubenberger C, Kashala O, Zwickl M, Stief A, Sansig G, Schläpfer B, Linkert S, van der Putten H, Hardman N, Schröder M.

J Immunol Methods. 1998 Jun 1;215(1-2):27-37.

PMID:
9744745
6.

B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

Chen J, Trounstine M, Kurahara C, Young F, Kuo CC, Xu Y, Loring JF, Alt FW, Huszar D.

EMBO J. 1993 Mar;12(3):821-30.

7.

Characterization of monoclonal antibodies recognizing immunoglobulin kappa and lambda chains in pigs by flow cytometry.

Sinkora J, Rehakova Z, Samankova L, Haverson K, Butler JE, Zwart R, Boersma W.

Vet Immunol Immunopathol. 2001 Jul 20;80(1-2):79-91.

PMID:
11445220
9.

The pre-immune variable kappa repertoire of swine is selectively generated from certain subfamilies of Vkappa2 and one Jkappa gene.

Butler JE, Wertz N, Sun J, Wang H, Lemke C, Chardon P, Piumi F, Wells K.

Vet Immunol Immunopathol. 2005 Oct 18;108(1-2):127-37.

PMID:
16112743
10.

Expression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements.

Oberdoerffer P, Novobrantseva TI, Rajewsky K.

J Exp Med. 2003 May 5;197(9):1165-72. Epub 2003 Apr 28. Erratum in: J Exp Med. 2003 May 19;1399.

11.

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies.

Tomizuka K, Shinohara T, Yoshida H, Uejima H, Ohguma A, Tanaka S, Sato K, Oshimura M, Ishida I.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):722-7.

12.

Antibody repertoire development in fetal and neonatal pigs. VII. Characterization of the preimmune kappa light chain repertoire.

Butler JE, Wertz N, Sun J, Wang H, Chardon P, Piumi F, Wells K.

J Immunol. 2004 Dec 1;173(11):6794-805.

13.

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes.

McBride OW, Hieter PA, Hollis GF, Swan D, Otey MC, Leder P.

J Exp Med. 1982 May 1;155(5):1480-90.

14.

Analysis of the structural integrity of YACs comprising human immunoglobulin genes in yeast and in embryonic stem cells.

Mendez MJ, Abderrahim H, Noguchi M, David NE, Hardy MC, Green LL, Tsuda H, Yoast S, Maynard-Currie CE, Garza D, et al.

Genomics. 1995 Mar 20;26(2):294-307.

PMID:
7601456
16.

Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus.

van der Burg M, Tümkaya T, Boerma M, de Bruin-Versteeg S, Langerak AW, van Dongen JJ.

Blood. 2001 Feb 15;97(4):1001-8.

17.

The Ig light chain restricted B6.kappa(-)lambda(SEG) mouse strain suggests that the IGL locus genomic organization is subject to constant evolution.

Amrani YM, Voegtlé D, Montagutelli X, Cazenave PA, Six A.

Immunogenetics. 2002 May;54(2):106-19. Epub 2002 Apr 5.

PMID:
12037603
18.

IgD/lambda plasmocytoma with immunoglobulin kappa light-chain genes in the germ-line configuration.

Hauke G, Epplen JT, Chluba J, Hollmann A, Peter HH.

J Clin Immunol. 1988 Sep;8(5):407-13.

PMID:
3141452
19.

Immunoglobulin kappa light chain germ-line transcripts in human precursor B lymphocytes.

Thompson A, Timmers E, Kenter MJ, Kraakman ME, Hendriks RW, Schuurman RK.

Eur J Immunol. 1992 Dec;22(12):3167-71.

PMID:
1446707
20.

B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain.

Pewzner-Jung Y, Friedmann D, Sonoda E, Jung S, Rajewsky K, Eilat D.

J Immunol. 1998 Nov 1;161(9):4634-45.

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