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Items: 1 to 20 of 116


Linking changes in epithelial morphogenesis to cancer mutations using computational modeling.

Rejniak KA, Wang SE, Bryce NS, Chang H, Parvin B, Jourquin J, Estrada L, Gray JW, Arteaga CL, Weaver AM, Quaranta V, Anderson AR.

PLoS Comput Biol. 2010 Aug 26;6(8). pii: e1000900. doi: 10.1371/journal.pcbi.1000900.


Phenotypic transition maps of 3D breast acini obtained by imaging-guided agent-based modeling.

Tang J, Enderling H, Becker-Weimann S, Pham C, Polyzos A, Chen CY, Costes SV.

Integr Biol (Camb). 2011 Apr;3(4):408-21. doi: 10.1039/c0ib00092b. Epub 2011 Mar 4.


LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.

Chang J, Nicolau MM, Cox TR, Wetterskog D, Martens JW, Barker HE, Erler JT.

Breast Cancer Res. 2013;15(4):R67.


A complex 3D human tissue culture system based on mammary stromal cells and silk scaffolds for modeling breast morphogenesis and function.

Wang X, Sun L, Maffini MV, Soto A, Sonnenschein C, Kaplan DL.

Biomaterials. 2010 May;31(14):3920-9. doi: 10.1016/j.biomaterials.2010.01.118. Epub 2010 Feb 24.


Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation.

Yu M, Lin G, Arshadi N, Kalatskaya I, Xue B, Haider S, Nguyen F, Boutros PC, Elson A, Muthuswamy LB, Tonks NK, Muthuswamy SK.

Mol Cell Biol. 2012 Oct;32(19):3913-24. doi: 10.1128/MCB.00068-12. Epub 2012 Jul 30.


Expression Pattern of the Pro-apoptotic Gene PAR-4 During the Morphogenesis of MCF-10A Human Mammary Epithelial Cells.

de Bessa Garcia SA, Pereira MC, Nagai MA.

Cancer Microenviron. 2010 Dec 21;4(1):33-8. doi: 10.1007/s12307-010-0059-y.


Disruption of 3D MCF-12A breast cell cultures by estrogens--an in vitro model for ER-mediated changes indicative of hormonal carcinogenesis.

Marchese S, Silva E.

PLoS One. 2012;7(10):e45767. doi: 10.1371/journal.pone.0045767. Epub 2012 Oct 2.


Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.

Reginato MJ, Mills KR, Becker EB, Lynch DK, Bonni A, Muthuswamy SK, Brugge JS.

Mol Cell Biol. 2005 Jun;25(11):4591-601.


Lumen formation during mammary epithelial morphogenesis: insights from in vitro and in vivo models.

Mailleux AA, Overholtzer M, Brugge JS.

Cell Cycle. 2008 Jan 1;7(1):57-62. Epub 2007 Oct 9. Review.


A computational study of the development of epithelial acini: I. Sufficient conditions for the formation of a hollow structure.

Rejniak KA, Anderson AR.

Bull Math Biol. 2008 Apr;70(3):677-712. doi: 10.1007/s11538-007-9274-1. Epub 2008 Jan 11.


Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly.

Wang H, Lacoche S, Huang L, Xue B, Muthuswamy SK.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):163-8. doi: 10.1073/pnas.1201141110. Epub 2012 Dec 17.


Quantitative analysis of three-dimensional human mammary epithelial tissue architecture reveals a role for tenascin-C in regulating c-met function.

Taraseviciute A, Vincent BT, Schedin P, Jones PL.

Am J Pathol. 2010 Feb;176(2):827-38. doi: 10.2353/ajpath.2010.090006. Epub 2009 Dec 30.


DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer.

Lott ST, Chen N, Chandler DS, Yang Q, Wang L, Rodriguez M, Xie H, Balasenthil S, Buchholz TA, Sahin AA, Chaung K, Zhang B, Olufemi SE, Chen J, Adams H, Band V, El-Naggar AK, Frazier ML, Keyomarsi K, Hunt KK, Sen S, Haffty B, Hewitt SM, Krahe R, Killary AM.

PLoS Med. 2009 May 26;6(5):e1000068. doi: 10.1371/journal.pmed.1000068. Epub 2009 May 5.


Cyclic AMP regulates formation of mammary epithelial acini in vitro.

Nedvetsky PI, Kwon SH, Debnath J, Mostov KE.

Mol Biol Cell. 2012 Aug;23(15):2973-81. doi: 10.1091/mbc.E12-02-0078. Epub 2012 Jun 6.


Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells.

Vaapil M, Helczynska K, Villadsen R, Petersen OW, Johansson E, Beckman S, Larsson C, Påhlman S, Jögi A.

PLoS One. 2012;7(9):e46543. doi: 10.1371/journal.pone.0046543. Epub 2012 Sep 28.


Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro.

Nowak M, Freudenberg U, Tsurkan MV, Werner C, Levental KR.

Biomaterials. 2017 Jan;112:20-30. doi: 10.1016/j.biomaterials.2016.10.007. Epub 2016 Oct 6.


Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling.

Pradeep CR, Köstler WJ, Lauriola M, Granit RZ, Zhang F, Jacob-Hirsch J, Rechavi G, Nair HB, Hennessy BT, Gonzalez-Angulo AM, Tekmal RR, Ben-Porath I, Mills GB, Domany E, Yarden Y.

Oncogene. 2012 Feb 16;31(7):907-17. doi: 10.1038/onc.2011.279. Epub 2011 Jul 11.


Three-dimensional Mammary Epithelial Cell Morphogenesis Model for Analysis of TGFß Signaling.

Rashidian J, Luo K.

Methods Mol Biol. 2016;1344:121-35. doi: 10.1007/978-1-4939-2966-5_7.


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