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Items: 1 to 20 of 92

1.

Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes.

Li Z, Cai H, Hassink M, Blackman ML, Brown RC, Conti PS, Fox JM.

Chem Commun (Camb). 2010 Nov 14;46(42):8043-5. doi: 10.1039/c0cc03078c. Epub 2010 Sep 22.

2.

Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin αvβ₃ targeted PET tracer based on a cyclic RGD peptide.

Selvaraj R, Liu S, Hassink M, Huang CW, Yap LP, Park R, Fox JM, Li Z, Conti PS.

Bioorg Med Chem Lett. 2011 Sep 1;21(17):5011-4. doi: 10.1016/j.bmcl.2011.04.116. Epub 2011 May 4.

3.

Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation.

Selvaraj R, Giglio B, Liu S, Wang H, Wang M, Yuan H, Chintala SR, Yap LP, Conti PS, Fox JM, Li Z.

Bioconjug Chem. 2015 Mar 18;26(3):435-42. doi: 10.1021/acs.bioconjchem.5b00089. Epub 2015 Mar 4.

4.

Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity.

Blackman ML, Royzen M, Fox JM.

J Am Chem Soc. 2008 Oct 15;130(41):13518-9. doi: 10.1021/ja8053805. Epub 2008 Sep 18.

5.

Efficient 18F labeling of cysteine-containing peptides and proteins using tetrazine-trans-cyclooctene ligation.

Liu S, Hassink M, Selvaraj R, Yap LP, Park R, Wang H, Chen X, Fox JM, Li Z, Conti PS.

Mol Imaging. 2013 Mar-Apr;12(2):121-8.

6.

Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation.

Herth MM, Andersen VL, Lehel S, Madsen J, Knudsen GM, Kristensen JL.

Chem Commun (Camb). 2013 May 8;49(36):3805-7. doi: 10.1039/c3cc41027g. Epub 2013 Mar 27.

PMID:
23535705
7.

(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

Meyer JP, Houghton JL, Kozlowski P, Abdel-Atti D, Reiner T, Pillarsetty NV, Scholz WW, Zeglis BM, Lewis JS.

Bioconjug Chem. 2016 Feb 17;27(2):298-301. doi: 10.1021/acs.bioconjchem.5b00504. Epub 2015 Oct 28.

8.

Conformationally Strained trans-Cyclooctene (sTCO) Enables the Rapid Construction of (18)F-PET Probes via Tetrazine Ligation.

Wang M, Svatunek D, Rohlfing K, Liu Y, Wang H, Giglio B, Yuan H, Wu Z, Li Z, Fox J.

Theranostics. 2016 Apr 12;6(6):887-95. doi: 10.7150/thno.14742. eCollection 2016.

9.

Trans-cyclooctene tag with improved properties for tumor pretargeting with the diels-alder reaction.

Rossin R, van Duijnhoven SM, Läppchen T, van den Bosch SM, Robillard MS.

Mol Pharm. 2014 Sep 2;11(9):3090-6. doi: 10.1021/mp500275a. Epub 2014 Aug 13.

PMID:
25077373
10.

Site-specific labeling of proteins and peptides with trans-cyclooctene containing handles capable of tetrazine ligation.

Wollack JW, Monson BJ, Dozier JK, Dalluge JJ, Poss K, Hilderbrand SA, Distefano MD.

Chem Biol Drug Des. 2014 Aug;84(2):140-7. doi: 10.1111/cbdd.12303. Epub 2014 May 13.

11.

Diels-Alder reaction for tumor pretargeting: in vivo chemistry can boost tumor radiation dose compared with directly labeled antibody.

Rossin R, Läppchen T, van den Bosch SM, Laforest R, Robillard MS.

J Nucl Med. 2013 Nov;54(11):1989-95. doi: 10.2967/jnumed.113.123745. Epub 2013 Oct 3.

12.

Highly reactive trans-cyclooctene tags with improved stability for Diels-Alder chemistry in living systems.

Rossin R, van den Bosch SM, Ten Hoeve W, Carvelli M, Versteegen RM, Lub J, Robillard MS.

Bioconjug Chem. 2013 Jul 17;24(7):1210-7. doi: 10.1021/bc400153y. Epub 2013 Jun 18.

PMID:
23725393
13.

Harnessing the bioorthogonal inverse electron demand Diels-Alder cycloaddition for pretargeted PET imaging.

Reiner T, Lewis JS, Zeglis BM.

J Vis Exp. 2015 Feb 3;(96):e52335. doi: 10.3791/52335.

14.

Azide and trans-cyclooctene dUTPs: incorporation into DNA probes and fluorescent click-labelling.

Ren X, El-Sagheer AH, Brown T.

Analyst. 2015 Apr 21;140(8):2671-8. doi: 10.1039/c5an00158g.

PMID:
25734317
15.

In vivo evaluation of (18)F-labeled TCO for pre-targeted PET imaging in the brain.

Wyffels L, Thomae D, Waldron AM, Fissers J, Dedeurwaerdere S, Van der Veken P, Joossens J, Stroobants S, Augustyns K, Staelens S.

Nucl Med Biol. 2014 Jul;41(6):513-23. doi: 10.1016/j.nucmedbio.2014.03.023. Epub 2014 Apr 2.

PMID:
24768149
16.

(18)F-labeled-bioorthogonal liposomes for in vivo targeting.

Emmetiere F, Irwin C, Viola-Villegas NT, Longo V, Cheal SM, Zanzonico P, Pillarsetty N, Weber WA, Lewis JS, Reiner T.

Bioconjug Chem. 2013 Nov 20;24(11):1784-9. doi: 10.1021/bc400322h. Epub 2013 Nov 7.

17.

Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions.

Lang K, Davis L, Wallace S, Mahesh M, Cox DJ, Blackman ML, Fox JM, Chin JW.

J Am Chem Soc. 2012 Jun 27;134(25):10317-20. doi: 10.1021/ja302832g. Epub 2012 Jun 13.

18.

Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.

Kurra Y, Odoi KA, Lee YJ, Yang Y, Lu T, Wheeler SE, Torres-Kolbus J, Deiters A, Liu WR.

Bioconjug Chem. 2014 Sep 17;25(9):1730-8. doi: 10.1021/bc500361d. Epub 2014 Sep 4.

19.

Microarray immobilization of biomolecules using a fast trans-cyclooctene (TCO)-tetrazine reaction.

Wang P, Na Z, Fu J, Tan CY, Zhang H, Yao SQ, Sun H.

Chem Commun (Camb). 2014 Oct 14;50(80):11818-21. doi: 10.1039/c4cc03838j.

PMID:
25052778
20.

Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.

Zhu J, Li S, Wängler C, Wängler B, Lennox RB, Schirrmacher R.

Chem Commun (Camb). 2015 Aug 11;51(62):12415-8. doi: 10.1039/c5cc03623b.

PMID:
26145162

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