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Items: 1 to 20 of 182

1.

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

Lugthart S, Figueroa ME, Bindels E, Skrabanek L, Valk PJ, Li Y, Meyer S, Erpelinck-Verschueren C, Greally J, Löwenberg B, Melnick A, Delwel R.

Blood. 2011 Jan 6;117(1):234-41. doi: 10.1182/blood-2010-04-281337. Epub 2010 Sep 20.

2.

Deregulated expression of EVI1 defines a poor prognostic subset of MLL-rearranged acute myeloid leukemias: a study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group.

Gröschel S, Schlenk RF, Engelmann J, Rockova V, Teleanu V, Kühn MW, Eiwen K, Erpelinck C, Havermans M, Lübbert M, Germing U, Schmidt-Wolf IG, Beverloo HB, Schuurhuis GJ, Ossenkoppele GJ, Schlegelberger B, Verdonck LF, Vellenga E, Verhoef G, Vandenberghe P, Pabst T, Bargetzi M, Krauter J, Ganser A, Valk PJ, Löwenberg B, Döhner K, Döhner H, Delwel R.

J Clin Oncol. 2013 Jan 1;31(1):95-103. doi: 10.1200/JCO.2011.41.5505. Epub 2012 Sep 24.

PMID:
23008312
3.

EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.

Bindels EM, Havermans M, Lugthart S, Erpelinck C, Wocjtowicz E, Krivtsov AV, Rombouts E, Armstrong SA, Taskesen E, Haanstra JR, Beverloo HB, Döhner H, Hudson WA, Kersey JH, Delwel R, Kumar AR.

Blood. 2012 Jun 14;119(24):5838-49. doi: 10.1182/blood-2011-11-393827. Epub 2012 May 2.

4.

The leukemia-associated gene MDS1/EVI1 is a new type of GATA-binding transactivator.

Soderholm J, Kobayashi H, Mathieu C, Rowley JD, Nucifora G.

Leukemia. 1997 Mar;11(3):352-8.

PMID:
9067573
5.

Review: Aberrant EVI1 expression in acute myeloid leukaemia.

Hinai AA, Valk PJ.

Br J Haematol. 2016 Mar;172(6):870-8. doi: 10.1111/bjh.13898. Epub 2016 Jan 5. Review.

PMID:
26729571
6.

Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia.

Vázquez I, Maicas M, Cervera J, Agirre X, Marin-Béjar O, Marcotegui N, Vicente C, Lahortiga I, Gomez-Benito M, Carranza C, Valencia A, Brunet S, Lumbreras E, Prosper F, Gómez-Casares MT, Hernández-Rivas JM, Calasanz MJ, Sanz MA, Sierra J, Odero MD.

Haematologica. 2011 Oct;96(10):1448-56. doi: 10.3324/haematol.2011.040535. Epub 2011 Jul 12.

7.

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.

Maicas M, Vázquez I, Vicente C, García-Sánchez MA, Marcotegui N, Urquiza L, Calasanz MJ, Odero MD.

Oncogene. 2013 Apr 18;32(16):2069-78. doi: 10.1038/onc.2012.222. Epub 2012 Jun 11.

PMID:
22689058
8.

Aberrant expression of ecotropic viral integration site-1 in acute myeloid leukemia and acute lymphoblastic leukemia.

Su G, Lian X, Tan D, Tao H, Liu H, Chen S, Yin H, Wu D, Yin B.

Leuk Lymphoma. 2015 Feb;56(2):472-9. doi: 10.3109/10428194.2014.924118. Epub 2014 Jun 25.

PMID:
24828867
9.

Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.

Fisser MC, Rommer A, Steinleitner K, Heller G, Herbst F, Wiese M, Glimm H, Sill H, Wieser R.

Mol Carcinog. 2015 Dec;54(12):1815-9. doi: 10.1002/mc.22252. Epub 2014 Dec 9.

PMID:
25491945
10.

Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases.

Haferlach C, Bacher U, Grossmann V, Schindela S, Zenger M, Kohlmann A, Kern W, Haferlach T, Schnittger S.

Genes Chromosomes Cancer. 2012 Dec;51(12):1079-85. doi: 10.1002/gcc.21992. Epub 2012 Aug 8.

PMID:
22887804
11.

High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

Lugthart S, van Drunen E, van Norden Y, van Hoven A, Erpelinck CA, Valk PJ, Beverloo HB, Löwenberg B, Delwel R.

Blood. 2008 Apr 15;111(8):4329-37. doi: 10.1182/blood-2007-10-119230. Epub 2008 Feb 13.

12.

Expression and prognostic significance of different mRNA 5'-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission duration.

Haas K, Kundi M, Sperr WR, Esterbauer H, Ludwig WD, Ratei R, Koller E, Gruener H, Sauerland C, Fonatsch C, Valent P, Wieser R.

Genes Chromosomes Cancer. 2008 Apr;47(4):288-98. doi: 10.1002/gcc.20532.

PMID:
18181178
13.

High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities.

Gröschel S, Lugthart S, Schlenk RF, Valk PJ, Eiwen K, Goudswaard C, van Putten WJ, Kayser S, Verdonck LF, Lübbert M, Ossenkoppele GJ, Germing U, Schmidt-Wolf I, Schlegelberger B, Krauter J, Ganser A, Döhner H, Löwenberg B, Döhner K, Delwel R.

J Clin Oncol. 2010 Apr 20;28(12):2101-7. doi: 10.1200/JCO.2009.26.0646. Epub 2010 Mar 22.

PMID:
20308656
14.

EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2.

Gómez-Benito M, Conchillo A, García MA, Vázquez I, Maicas M, Vicente C, Cristobal I, Marcotegui N, García-Ortí L, Bandrés E, Calasanz MJ, Alonso MM, Odero MD.

Br J Cancer. 2010 Oct 12;103(8):1292-6. doi: 10.1038/sj.bjc.6605874. Epub 2010 Sep 14.

15.

Quantification of EVI1 transcript levels in acute myeloid leukemia by RT-qPCR analysis: A study by the ALFA Group.

Smol T, Nibourel O, Marceau-Renaut A, Celli-Lebras K, Berthon C, Quesnel B, Boissel N, Terré C, Thomas X, Castaigne S, Dombret H, Preudhomme C, Renneville A.

Leuk Res. 2015 Dec;39(12):1443-7. doi: 10.1016/j.leukres.2015.09.021. Epub 2015 Oct 9.

PMID:
26467814
16.

EVI1 up-regulates the stress responsive gene SIRT1 which triggers deacetylation and degradation of EVI1.

Pradhan AK, Kuila N, Singh S, Chakraborty S.

Biochim Biophys Acta. 2011 Apr-Jun;1809(4-6):269-75. doi: 10.1016/j.bbagrm.2011.04.007. Epub 2011 Apr 30.

PMID:
21555002
17.

[Clinical and biological characteristics of childhood acute myeloid leukemia with EVI1 gene positive expression].

Jiang M, Li XQ, Hu D, Qiu YN, Zhang ZQ, Zhang BY, Han J, Jin RM.

Zhongguo Dang Dai Er Ke Za Zhi. 2014 Feb;16(2):129-34. Chinese.

18.
19.

EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations.

Lavallée VP, Gendron P, Lemieux S, D'Angelo G, Hébert J, Sauvageau G.

Blood. 2015 Jan 1;125(1):140-3. doi: 10.1182/blood-2014-07-591529. Epub 2014 Oct 20.

20.

Angiopoietin1 contributes to the maintenance of cell quiescence in EVI1(high) leukemia cells.

Ichihara E, Kaneda K, Saito Y, Yamakawa N, Morishita K.

Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):239-45. doi: 10.1016/j.bbrc.2011.10.061. Epub 2011 Oct 18.

PMID:
22033412

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