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Items: 1 to 20 of 145

1.

High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules.

Andrews PD, Becroft M, Aspegren A, Gilmour J, James MJ, McRae S, Kime R, Allcock RW, Abraham A, Jiang Z, Strehl R, Mountford JC, Milligan G, Houslay MD, Adams DR, Frearson JA.

Biochem J. 2010 Nov 15;432(1):21-33. doi: 10.1042/BJ20101022.

PMID:
20854259
2.

Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells.

Takehara T, Teramura T, Onodera Y, Kakegawa R, Fukunaga N, Takenoshita M, Sagawa N, Fukuda K, Hosoi Y.

Mol Hum Reprod. 2008 Nov;14(11):627-34. doi: 10.1093/molehr/gan061. Epub 2008 Oct 21.

3.

The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.

Emre N, Vidal JG, Elia J, O'Connor ED, Paramban RI, Hefferan MP, Navarro R, Goldberg DS, Varki NM, Marsala M, Carson CT.

PLoS One. 2010 Aug 13;5(8):e12148. doi: 10.1371/journal.pone.0012148.

4.

Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation.

Braam SR, Nauw R, Ward-van Oostwaard D, Mummery C, Passier R.

Ann N Y Acad Sci. 2010 Feb;1188:52-7. doi: 10.1111/j.1749-6632.2009.05083.x.

PMID:
20201886
5.

The effect of Rho-associated kinase inhibition on the proteome pattern of dissociated human embryonic stem cells.

Gharechahi J, Pakzad M, Mirshavaladi S, Sharifitabar M, Baharvand H, Salekdeh GH.

Mol Biosyst. 2014 Mar 4;10(3):640-52. doi: 10.1039/c3mb70255c. Epub 2014 Jan 15.

PMID:
24430196
6.

ROCK inhibitor improves survival of cryopreserved serum/feeder-free single human embryonic stem cells.

Li X, Krawetz R, Liu S, Meng G, Rancourt DE.

Hum Reprod. 2009 Mar;24(3):580-9. doi: 10.1093/humrep/den404. Epub 2008 Dec 4.

PMID:
19056770
7.

Enhanced generation of human embryonic stem cells from single blastomeres of fair and poor-quality cleavage embryos via inhibition of glycogen synthase kinase β and Rho-associated kinase signaling.

Taei A, Hassani SN, Eftekhari-Yazdi P, Rezazadeh Valojerdi M, Nokhbatolfoghahai M, Masoudi NS, Pakzad M, Gourabi H, Baharvand H.

Hum Reprod. 2013 Oct;28(10):2661-71. doi: 10.1093/humrep/det309. Epub 2013 Aug 6.

PMID:
23925393
8.

Novel cryopreservation method for dissociated human embryonic stem cells in the presence of a ROCK inhibitor.

Martin-Ibañez R, Unger C, Strömberg A, Baker D, Canals JM, Hovatta O.

Hum Reprod. 2008 Dec;23(12):2744-54. doi: 10.1093/humrep/den316. Epub 2008 Aug 20.

PMID:
18716037
9.

The ROCK inhibitor Y-26732 enhances the survival and proliferation of human embryonic stem cell-derived neural progenitor cells upon dissociation.

Rungsiwiwut R, Manolertthewan C, Numchaisrika P, Ahnonkitpanit V, Virutamasen P, Techakumphu M, Pruksananonda K.

Cells Tissues Organs. 2013;198(2):127-38. doi: 10.1159/000354031. Epub 2013 Oct 19.

PMID:
24158103
10.

A ROCK inhibitor permits survival of dissociated human embryonic stem cells.

Watanabe K, Ueno M, Kamiya D, Nishiyama A, Matsumura M, Wataya T, Takahashi JB, Nishikawa S, Nishikawa S, Muguruma K, Sasai Y.

Nat Biotechnol. 2007 Jun;25(6):681-6. Epub 2007 May 27.

PMID:
17529971
11.

ROCK inhibitor Y-27632 enhances the survivability of dissociated buffalo (Bubalus bubalis) embryonic stem cell-like cells.

Sharma R, George A, Chauhan MS, Singla S, Manik RS, Palta P.

Reprod Fertil Dev. 2013;25(2):446-55. doi: 10.1071/RD11315.

PMID:
22951036
12.

Effect of ROCK inhibitor Y-27632 on normal and variant human embryonic stem cells (hESCs) in vitro: its benefits in hESC expansion.

Gauthaman K, Fong CY, Bongso A.

Stem Cell Rev. 2010 Mar;6(1):86-95. doi: 10.1007/s12015-009-9107-8. Epub 2009 Dec 15.

PMID:
20013076
13.

Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.

Morwick T, Büttner FH, Cywin CL, Dahmann G, Hickey E, Jakes S, Kaplita P, Kashem MA, Kerr S, Kugler S, Mao W, Marshall D, Paw Z, Shih CK, Wu F, Young E.

J Med Chem. 2010 Jan 28;53(2):759-77. doi: 10.1021/jm9014263.

PMID:
20000469
14.

Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality embryos.

Cortes JL, Sanchez L, Ligero G, Gutierrez-Aranda I, Catalina P, Elosua C, Leone PE, Montes R, Bueno C, Ramos-Mejía V, Maleno I, García-Pérez JL, Menendez P.

Hum Reprod. 2009 Aug;24(8):1844-51. doi: 10.1093/humrep/dep107. Epub 2009 Apr 28.

PMID:
19401322
15.

Human embryonic stem cells: caught between a ROCK inhibitor and a hard place.

Krawetz RJ, Li X, Rancourt DE.

Bioessays. 2009 Mar;31(3):336-43. doi: 10.1002/bies.200800157.

PMID:
19260014
16.
17.

Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.

Chayosumrit M, Tuch B, Sidhu K.

Biomaterials. 2010 Jan;31(3):505-14. doi: 10.1016/j.biomaterials.2009.09.071. Epub 2009 Oct 14.

PMID:
19833385
18.

Promotion of mouse embryonic stem cell differentiation by Rho kinase inhibitor Y-27632.

Kamishibahara Y, Kawaguchi H, Shimizu N.

Neurosci Lett. 2014 Sep 5;579:58-63. doi: 10.1016/j.neulet.2014.07.011. Epub 2014 Jul 17.

PMID:
25038419
19.

Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging.

Pakzad M, Totonchi M, Taei A, Seifinejad A, Hassani SN, Baharvand H.

Stem Cell Rev. 2010 Mar;6(1):96-107. doi: 10.1007/s12015-009-9103-z.

PMID:
20012714
20.

Cryopreservation of dissociated human embryonic stem cells in the presence of ROCK inhibitor.

Martín-Ibáñez R, Strömberg AM, Hovatta O, Canals JM.

Curr Protoc Stem Cell Biol. 2009 Jul;Chapter 1:Unit 1C.8. doi: 10.1002/9780470151808.sc01c08s10.

PMID:
19585460

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