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Items: 1 to 20 of 204

1.

The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease.

Liu D, Pitta M, Lee JH, Ray B, Lahiri DK, Furukawa K, Mughal M, Jiang H, Villarreal J, Cutler RG, Greig NH, Mattson MP.

J Alzheimers Dis. 2010;22(2):443-57. doi: 10.3233/JAD-2010-101017.

2.

NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice.

Goussakov I, Miller MB, Stutzmann GE.

J Neurosci. 2010 Sep 8;30(36):12128-37. doi: 10.1523/JNEUROSCI.2474-10.2010.

3.

Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease.

Rothman SM, Herdener N, Frankola KA, Mughal MR, Mattson MP.

Brain Res. 2013 Sep 5;1529:200-8. doi: 10.1016/j.brainres.2013.07.010. Epub 2013 Jul 13.

4.

Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.

Oulès B, Del Prete D, Greco B, Zhang X, Lauritzen I, Sevalle J, Moreno S, Paterlini-Bréchot P, Trebak M, Checler F, Benfenati F, Chami M.

J Neurosci. 2012 Aug 22;32(34):11820-34.

5.

Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease.

Caccamo A, Branca C, Talboom JS, Shaw DM, Turner D, Ma L, Messina A, Huang Z, Wu J, Oddo S.

J Neurosci. 2015 Oct 14;35(41):14042-56. doi: 10.1523/JNEUROSCI.2781-15.2015.

6.

Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease.

Tapia-Rojas C, Aranguiz F, Varela-Nallar L, Inestrosa NC.

Brain Pathol. 2016 Jan;26(1):62-74. doi: 10.1111/bpa.12255. Epub 2015 May 7.

PMID:
25763997
8.

Recombinant soluble neprilysin reduces amyloid-beta accumulation and improves memory impairment in Alzheimer's disease mice.

Park MH, Lee JK, Choi S, Ahn J, Jin HK, Park JS, Bae JS.

Brain Res. 2013 Sep 5;1529:113-24. doi: 10.1016/j.brainres.2013.05.045. Epub 2013 Jul 2.

PMID:
23831521
9.

Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology.

Isopi E, Granzotto A, Corona C, Bomba M, Ciavardelli D, Curcio M, Canzoniero LM, Navarra R, Lattanzio R, Piantelli M, Sensi SL.

Neurobiol Dis. 2015 Sep;81:214-24. doi: 10.1016/j.nbd.2014.11.013. Epub 2014 Nov 28.

PMID:
25434488
10.

Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease.

Li L, Zhang S, Zhang X, Li T, Tang Y, Liu H, Yang W, Le W.

Curr Alzheimer Res. 2013 May 1;10(4):433-41.

PMID:
23305067
11.

3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress.

Rothman SM, Herdener N, Camandola S, Texel SJ, Mughal MR, Cong WN, Martin B, Mattson MP.

Neurobiol Aging. 2012 Apr;33(4):830.e1-12. doi: 10.1016/j.neurobiolaging.2011.07.005. Epub 2011 Aug 19.

12.

Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.

España J, Giménez-Llort L, Valero J, Miñano A, Rábano A, Rodriguez-Alvarez J, LaFerla FM, Saura CA.

Biol Psychiatry. 2010 Mar 15;67(6):513-21. doi: 10.1016/j.biopsych.2009.06.015. Epub 2009 Aug 7.

PMID:
19664757
13.

L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.

Wang Y, Mattson MP.

Neurobiol Aging. 2014 Jan;35(1):88-95. doi: 10.1016/j.neurobiolaging.2013.07.007. Epub 2013 Aug 7.

14.

Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance.

Zhu Z, Yan J, Jiang W, Yao XG, Chen J, Chen L, Li C, Hu L, Jiang H, Shen X.

J Neurosci. 2013 Aug 7;33(32):13138-49. doi: 10.1523/JNEUROSCI.4790-12.2013.

15.

Spatial Memory Impairment is Associated with Intraneural Amyloid-β Immunoreactivity and Dysfunctional Arc Expression in the Hippocampal-CA3 Region of a Transgenic Mouse Model of Alzheimer's Disease.

Morin JP, Cerón-Solano G, Velázquez-Campos G, Pacheco-López G, Bermúdez-Rattoni F, Díaz-Cintra S.

J Alzheimers Dis. 2016;51(1):69-79. doi: 10.3233/JAD-150975.

PMID:
26836189
16.

Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with Homer1a.

Yamamoto K, Ueta Y, Wang L, Yamamoto R, Inoue N, Inokuchi K, Aiba A, Yonekura H, Kato N.

J Neurosci. 2011 Aug 3;31(31):11100-9. doi: 10.1523/JNEUROSCI.6752-10.2011.

17.

Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.

McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A.

Brain Res. 2008 May 1;1207:225-36. doi: 10.1016/j.brainres.2008.01.095. Epub 2008 Feb 16.

18.

Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.

Choi SH, Aid S, Caracciolo L, Minami SS, Niikura T, Matsuoka Y, Turner RS, Mattson MP, Bosetti F.

J Neurochem. 2013 Jan;124(1):59-68. doi: 10.1111/jnc.12059. Epub 2012 Nov 21.

19.

Dietary supplementation with S-adenosyl methionine delayed amyloid-β and tau pathology in 3xTg-AD mice.

Lee S, Lemere CA, Frost JL, Shea TB.

J Alzheimers Dis. 2012;28(2):423-31. doi: 10.3233/JAD-2011-111025.

PMID:
22045486

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