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Items: 1 to 20 of 119


Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation, and functional evaluation.

Gupta S, Ghosh SK, Scott ME, Bainbridge B, Jiang B, Lamont RJ, McCormick TS, Weinberg A.

J Biol Chem. 2010 Nov 19;285(47):36523-31. doi: 10.1074/jbc.M110.133140. Epub 2010 Sep 16.


FAD-I, a Fusobacterium nucleatum Cell Wall-Associated Diacylated Lipoprotein That Mediates Human Beta Defensin 2 Induction through Toll-Like Receptor-1/2 (TLR-1/2) and TLR-2/6.

Bhattacharyya S, Ghosh SK, Shokeen B, Eapan B, Lux R, Kiselar J, Nithianantham S, Young A, Pandiyan P, McCormick TS, Weinberg A.

Infect Immun. 2016 Apr 22;84(5):1446-1456. doi: 10.1128/IAI.01311-15. Print 2016 May.


Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells.

Ji S, Shin JE, Kim YS, Oh JE, Min BM, Choi Y.

Infect Immun. 2009 Mar;77(3):1044-52. doi: 10.1128/IAI.00449-08. Epub 2008 Dec 22.


Fusobacterium nucleatum and human beta-defensins modulate the release of antimicrobial chemokine CCL20/macrophage inflammatory protein 3α.

Ghosh SK, Gupta S, Jiang B, Weinberg A.

Infect Immun. 2011 Nov;79(11):4578-87. doi: 10.1128/IAI.05586-11. Epub 2011 Sep 12.


Conceptual Perspectives: Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human Host.

Ghosh SK, Feng Z, Fujioka H, Lux R, McCormick TS, Weinberg A.

Front Microbiol. 2018 Feb 26;9:302. doi: 10.3389/fmicb.2018.00302. eCollection 2018.


TLR2 sensing of F. nucleatum and S. sanguinis distinctly triggered gingival innate response.

Peyret-Lacombe A, Brunel G, Watts M, Charveron M, Duplan H.

Cytokine. 2009 May;46(2):201-10. doi: 10.1016/j.cyto.2009.01.006. Epub 2009 Mar 18.


Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria.

Yin L, Chino T, Horst OV, Hacker BM, Clark EA, Dale BA, Chung WO.

BMC Immunol. 2010 Jul 9;11:37. doi: 10.1186/1471-2172-11-37.


Interplay of protease-activated receptors and NOD pattern recognition receptors in epithelial innate immune responses to bacteria.

Chung WO, An JY, Yin L, Hacker BM, Rohani MG, Dommisch H, DiJulio DH.

Immunol Lett. 2010 Jul 8;131(2):113-9. doi: 10.1016/j.imlet.2010.02.006. Epub 2010 Feb 26.


Coinfection with Fusobacterium nucleatum can enhance the attachment and invasion of Porphyromonas gingivalis or Aggregatibacter actinomycetemcomitans to human gingival epithelial cells.

Li Y, Guo H, Wang X, Lu Y, Yang C, Yang P.

Arch Oral Biol. 2015 Sep;60(9):1387-93. doi: 10.1016/j.archoralbio.2015.06.017. Epub 2015 Jun 23.


Intracellular degradation of Fusobacterium nucleatum in human gingival epithelial cells.

Ji S, Shin JE, Kim YC, Choi Y.

Mol Cells. 2010 Dec;30(6):519-26. doi: 10.1007/s10059-010-0142-8. Epub 2010 Nov 5.


Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells.

Kumar A, Zhang J, Yu FS.

Microbes Infect. 2006 Feb;8(2):380-9. Epub 2005 Sep 15.


A periodontal pathogen Treponema denticola hijacks the Fusobacterium nucleatum-driven host response.

Shin JE, Baek KJ, Choi YS, Choi Y.

Immunol Cell Biol. 2013 Sep;91(8):503-10. doi: 10.1038/icb.2013.35. Epub 2013 Jul 30.


Intracellular calcium in signaling human beta-defensin-2 expression in oral epithelial cells.

Krisanaprakornkit S, Jotikasthira D, Dale BA.

J Dent Res. 2003 Nov;82(11):877-82.


Expression of the peptide antibiotic human beta-defensin 1 in cultured gingival epithelial cells and gingival tissue.

Krisanaprakornkit S, Weinberg A, Perez CN, Dale BA.

Infect Immun. 1998 Sep;66(9):4222-8.

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