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Items: 1 to 20 of 89

1.

Development and validation of an HPLC method for quantitation of BA-TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice.

Li H, Ezell SJ, Zhang X, Wang W, Xu H, Rayburn ER, Zhang X, Gurpinar E, Yang X, Sommers CI, Velu SE, Zhang R.

Biomed Chromatogr. 2011 May;25(5):628-34. doi: 10.1002/bmc.1498.

2.

Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats.

Yu JX, Voruganti S, Li DD, Qin JJ, Nag S, Xu S, Velu SE, Wang W, Zhang R.

Chin J Nat Med. 2015 Jul;13(7):554-60. doi: 10.1016/S1875-5364(15)30051-0.

3.

Preclinical evaluation of anticancer efficacy and pharmacological properties of FBA-TPQ, a novel synthetic makaluvamine analog.

Zhang X, Xu H, Zhang X, Voruganti S, Murugesan S, Nadkarni DH, Velu SE, Wang MH, Wang W, Zhang R.

Mar Drugs. 2012 May;10(5):1138-55. doi: 10.3390/md10051138.

4.

Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

Ezell SJ, Li H, Xu H, Zhang X, Gurpinar E, Zhang X, Rayburn ER, Sommers CI, Yang X, Velu SE, Wang W, Zhang R.

Mar Drugs. 2010 Jul 13;8(7):2129-41. doi: 10.3390/md8072129.

5.

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

Wang W, Rayburn ER, Velu SE, Chen D, Nadkarni DH, Murugesan S, Chen D, Zhang R.

Breast Cancer Res Treat. 2010 Sep;123(2):321-31. doi: 10.1007/s10549-009-0638-0.

6.

Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice.

Nag S, Qin JJ, Voruganti S, Wang MH, Sharma H, Patil S, Buolamwini JK, Wang W, Zhang R.

Biomed Chromatogr. 2015 May;29(5):654-63. doi: 10.1002/bmc.3327.

7.
8.

Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.

Chen D, Wang W, Qin JJ, Wang MH, Murugesan S, Nadkarni DH, Velu SE, Wang H, Zhang R.

Curr Cancer Drug Targets. 2013 Jul;13(6):651-60.

PMID:
23607596
9.

High-performance liquid chromatography analysis of a novel small-molecule, anti-cancer drug, Palomid 529, in human and mouse plasma and in mouse tissue homogenates.

Lin F, Sherris D, Beijnen JH, Van Tellingen O.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Dec 15;879(32):3823-31. doi: 10.1016/j.jchromb.2011.10.028.

PMID:
22100549
10.

Development and validation of a highly rapid and sensitive LC-MS/MS method for determination of SZ-685C, an investigational marine anticancer agent, in rat plasma--application to a pharmacokinetic study in rats.

Chen JY, Wang XD, Zhong GP, Qin XL, Li JL, Huang ZY, Zhu X, Li MF, Huang M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2127-34. doi: 10.1016/j.jchromb.2011.05.049.

PMID:
21703949
11.

Development and validation of a RP-HPLC method for the quantitation of tofacitinib in rat plasma and its application to a pharmacokinetic study.

S VK, Dhiman V, Giri KK, Sharma K, Zainuddin M, Mullangi R.

Biomed Chromatogr. 2015 Sep;29(9):1325-9. doi: 10.1002/bmc.3426.

PMID:
25622797
12.

Improved liquid chromatographic method for mitoxantrone quantification in mouse plasma and tissues to study the pharmacokinetics of a liposome entrapped mitoxantrone formulation.

Johnson JL, Ahmad A, Khan S, Wang YF, Abu-Qare AW, Ayoub JE, Zhang A, Ahmad I.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jan 5;799(1):149-55.

PMID:
14659447
14.

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

Wang W, Rayburn ER, Velu SE, Nadkarni DH, Murugesan S, Zhang R.

Clin Cancer Res. 2009 May 15;15(10):3511-8. doi: 10.1158/1078-0432.CCR-08-2689.

15.

High performance liquid chromatographic methods for the determination of aripiprazole with ultraviolet detection in rat plasma and brain: application to the pharmacokinetic study.

Shimokawa Y, Akiyama H, Kashiyama E, Koga T, Miyamoto G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jul 5;821(1):8-14.

PMID:
15897016
16.

Determination of desoxyepothilone B in nude mice plasma by liquid-liquid extraction and reversed-phase high-performance liquid chromatography.

Wang Z, Wang H, Rhie JK, Covey JM, Liang P, Wang S, Wang C, Hu Y, Prasad G, Nan L, Hill DL, Zhang R.

J Pharm Biomed Anal. 2006 Sep 18;42(2):272-6.

PMID:
16616824
17.

Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography.

de Vries NA, Ouwehand M, Buckle T, Beijnen JH, van Tellingen O.

Biomed Chromatogr. 2007 Nov;21(11):1191-200.

PMID:
17582233
18.

An HPLC-ultraviolet detection method for the determination of Z24 in mouse whole blood and its application to pharmacokinetic studies.

Sheng L, Li J, Zhang Z, Ruan J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 15;873(1):27-30. doi: 10.1016/j.jchromb.2008.05.037.

PMID:
18723410
19.
20.

Validation of HPLC analysis method of a novel antihypertensive agent MS23 in rat plasma.

Wang T, Fox LM, Wang D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 2;830(1):13-7.

PMID:
16257589
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