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Items: 1 to 20 of 127


Identification of acidic pH-dependent ligands of pentameric C-reactive protein.

Hammond DJ Jr, Singh SK, Thompson JA, Beeler BW, Rusiñol AE, Pangburn MK, Potempa LA, Agrawal A.

J Biol Chem. 2010 Nov 12;285(46):36235-44. doi: 10.1074/jbc.M110.142026. Epub 2010 Sep 14.


Exposing a hidden functional site of C-reactive protein by site-directed mutagenesis.

Singh SK, Thirumalai A, Hammond DJ Jr, Pangburn MK, Mishra VK, Johnson DA, Rusiñol AE, Agrawal A.

J Biol Chem. 2012 Jan 27;287(5):3550-8. doi: 10.1074/jbc.M111.310011. Epub 2011 Dec 9.


Functional Transformation of C-reactive Protein by Hydrogen Peroxide.

Singh SK, Thirumalai A, Pathak A, Ngwa DN, Agrawal A.

J Biol Chem. 2017 Feb 24;292(8):3129-3136. doi: 10.1074/jbc.M116.773176. Epub 2017 Jan 17.


Complement factor H binds to denatured rather than to native pentameric C-reactive protein.

Hakobyan S, Harris CL, van den Berg CW, Fernandez-Alonso MC, de Jorge EG, de Cordoba SR, Rivas G, Mangione P, Pepys MB, Morgan BP.

J Biol Chem. 2008 Nov 7;283(45):30451-60. doi: 10.1074/jbc.M803648200. Epub 2008 Sep 11.


Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrations.

Okemefuna AI, Nan R, Miller A, Gor J, Perkins SJ.

J Biol Chem. 2010 Jan 8;285(2):1053-65. doi: 10.1074/jbc.M109.044529. Epub 2009 Oct 22.


Atherosclerosis-related functions of C-reactive protein.

Agrawal A, Hammond DJ Jr, Singh SK.

Cardiovasc Hematol Disord Drug Targets. 2010 Dec 1;10(4):235-40.


Carbohydrate-binding properties of human neo-CRP and its relationship to phosphorylcholine-binding site.

Lee RT, Lee YC.

Glycobiology. 2003 Jan;13(1):11-21. Epub 2002 Oct 30.


Interaction of calcium-bound C-reactive protein with fibronectin is controlled by pH: in vivo implications.

Suresh MV, Singh SK, Agrawal A.

J Biol Chem. 2004 Dec 10;279(50):52552-7. Epub 2004 Sep 28.


Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H.

Mihlan M, Stippa S, Józsi M, Zipfel PF.

Cell Death Differ. 2009 Dec;16(12):1630-40. doi: 10.1038/cdd.2009.103. Epub 2009 Aug 14.


Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1.

Ling TY, Chen CL, Huang YH, Liu IH, Huang SS, Huang JS.

J Biol Chem. 2004 Sep 10;279(37):38736-48. Epub 2004 Jun 28.


Binding of the monomeric form of C-reactive protein to enzymatically-modified low-density lipoprotein: effects of phosphoethanolamine.

Singh SK, Suresh MV, Hammond DJ Jr, Rusiñol AE, Potempa LA, Agrawal A.

Clin Chim Acta. 2009 Aug;406(1-2):151-5. doi: 10.1016/j.cca.2009.06.018. Epub 2009 Jun 21.


A C-reactive protein mutant that does not bind to phosphocholine and pneumococcal C-polysaccharide.

Agrawal A, Simpson MJ, Black S, Carey MP, Samols D.

J Immunol. 2002 Sep 15;169(6):3217-22.


The physiological structure of human C-reactive protein and its complex with phosphocholine.

Thompson D, Pepys MB, Wood SP.

Structure. 1999 Feb 15;7(2):169-77.


Purification of recombinant C-reactive protein mutants.

Thirumalai A, Singh SK, Hammond DJ Jr, Gang TB, Ngwa DN, Pathak A, Agrawal A.

J Immunol Methods. 2017 Apr;443:26-32. doi: 10.1016/j.jim.2017.01.011. Epub 2017 Feb 3.


FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.

Csincsi ÁI, Szabó Z, Bánlaki Z, Uzonyi B, Cserhalmi M, Kárpáti É, Tortajada A, Caesar JJE, Prohászka Z, Jokiranta TS, Lea SM, Rodríguez de Córdoba S, Józsi M.

J Immunol. 2017 Jul 1;199(1):292-303. doi: 10.4049/jimmunol.1600483. Epub 2017 May 22.


Protein-directed immobilization of phosphocholine ligands on a gold surface for multivalent C-reactive protein binding.

Kim E, Lee SG, Kim HC, Lee SJ, Baek CS, Jeong SW.

Curr Top Med Chem. 2013;13(4):519-24. Review.


Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein.

McRae JL, Duthy TG, Griggs KM, Ormsby RJ, Cowan PJ, Cromer BA, McKinstry WJ, Parker MW, Murphy BF, Gordon DL.

J Immunol. 2005 May 15;174(10):6250-6.


Studies on the interactions between C-reactive protein and complement proteins.

Bíró A, Rovó Z, Papp D, Cervenak L, Varga L, Füst G, Thielens NM, Arlaud GJ, Prohászka Z.

Immunology. 2007 May;121(1):40-50. Epub 2007 Jan 18.

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