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Items: 1 to 20 of 209

1.

A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.

Fielding AB, Lim S, Montgomery K, Dobreva I, Dedhar S.

Oncogene. 2011 Feb 3;30(5):521-34. doi: 10.1038/onc.2010.431. Epub 2010 Sep 13.

PMID:
20838383
2.

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization.

Fielding AB, Dobreva I, McDonald PC, Foster LJ, Dedhar S.

J Cell Biol. 2008 Feb 25;180(4):681-9. doi: 10.1083/jcb.200710074. Epub 2008 Feb 18.

3.

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity.

LeRoy PJ, Hunter JJ, Hoar KM, Burke KE, Shinde V, Ruan J, Bowman D, Galvin K, Ecsedy JA.

Cancer Res. 2007 Jun 1;67(11):5362-70.

4.

Proteins required for centrosome clustering in cancer cells.

Leber B, Maier B, Fuchs F, Chi J, Riffel P, Anderhub S, Wagner L, Ho AD, Salisbury JL, Boutros M, Krämer A.

Sci Transl Med. 2010 May 26;2(33):33ra38. doi: 10.1126/scitranslmed.3000915.

5.

Plk1 regulates both ASAP localization and its role in spindle pole integrity.

Eot-Houllier G, Venoux M, Vidal-Eychenié S, Hoang MT, Giorgi D, Rouquier S.

J Biol Chem. 2010 Sep 17;285(38):29556-68. doi: 10.1074/jbc.M110.144220. Epub 2010 Jul 8.

6.

Beyond focal adhesions: integrin-linked kinase associates with tubulin and regulates mitotic spindle organization.

Fielding AB, Dobreva I, Dedhar S.

Cell Cycle. 2008 Jul 1;7(13):1899-906. Epub 2008 Apr 24.

PMID:
18604167
7.

Mitotic catastrophe and cell death induced by depletion of centrosomal proteins.

Kimura M, Yoshioka T, Saio M, Banno Y, Nagaoka H, Okano Y.

Cell Death Dis. 2013 Apr 18;4:e603. doi: 10.1038/cddis.2013.108.

8.

Regulation of mitotic cytoskeleton dynamics and cytokinesis by integrin-linked kinase in retinoblastoma cells.

Sikkema WK, Strikwerda A, Sharma M, Assi K, Salh B, Cox ME, Mills J.

PLoS One. 2014 Jun 9;9(6):e98838. doi: 10.1371/journal.pone.0098838. eCollection 2014.

9.

ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis.

Venoux M, Basbous J, Berthenet C, Prigent C, Fernandez A, Lamb NJ, Rouquier S.

Hum Mol Genet. 2008 Jan 15;17(2):215-24. Epub 2007 Oct 9.

PMID:
17925329
10.

p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.

Tritarelli A, Oricchio E, Ciciarello M, Mangiacasale R, Palena A, Lavia P, Soddu S, Cundari E.

Mol Biol Cell. 2004 Aug;15(8):3751-7. Epub 2004 Jun 4.

11.

Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication.

Christodoulou A, Lederer CW, Surrey T, Vernos I, Santama N.

J Cell Sci. 2006 May 15;119(Pt 10):2035-47. Epub 2006 Apr 25.

12.

The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival.

Schneider L, Essmann F, Kletke A, Rio P, Hanenberg H, Wetzel W, Schulze-Osthoff K, Nürnberg B, Piekorz RP.

J Biol Chem. 2007 Oct 5;282(40):29273-83. Epub 2007 Aug 5.

13.

Centrosomes and cancer: how cancer cells divide with too many centrosomes.

Godinho SA, Kwon M, Pellman D.

Cancer Metastasis Rev. 2009 Jun;28(1-2):85-98. doi: 10.1007/s10555-008-9163-6. Review.

PMID:
19156503
14.

BubR1 localizes to centrosomes and suppresses centrosome amplification via regulating Plk1 activity in interphase cells.

Izumi H, Matsumoto Y, Ikeuchi T, Saya H, Kajii T, Matsuura S.

Oncogene. 2009 Aug 6;28(31):2806-20. doi: 10.1038/onc.2009.141. Epub 2009 Jun 8.

PMID:
19503101
15.

The mitotic functions of integrin-linked kinase.

Fielding AB, Dedhar S.

Cancer Metastasis Rev. 2009 Jun;28(1-2):99-111. doi: 10.1007/s10555-008-9177-0. Review.

PMID:
19153670
16.

Functional characterization of AIBp, a novel Aurora-A binding protein in centrosome structure and spindle formation.

Lieu AS, Cheng TS, Chou CH, Wu CH, Hsu CY, Huang CY, Chang LK, Loh JK, Chang CS, Hsu CM, Howng SL, Hong YR.

Int J Oncol. 2010 Aug;37(2):429-36.

PMID:
20596670
17.

Integrin-linked kinase regulates interphase and mitotic microtubule dynamics.

Lim S, Kawamura E, Fielding AB, Maydan M, Dedhar S.

PLoS One. 2013;8(1):e53702. doi: 10.1371/journal.pone.0053702. Epub 2013 Jan 21.

18.

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S.

Cancer Res. 2008 Mar 15;68(6):1618-24. doi: 10.1158/0008-5472.CAN-07-5869.

19.

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.

Lin CH, Hu CK, Shih HM.

J Cell Biol. 2010 Jun 28;189(7):1097-105. doi: 10.1083/jcb.200911120. Epub 2010 Jun 21.

20.

Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen.

Rebacz B, Larsen TO, Clausen MH, Rønnest MH, Löffler H, Ho AD, Krämer A.

Cancer Res. 2007 Jul 1;67(13):6342-50.

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