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Items: 1 to 20 of 121


The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors.

Arun SN, Xie D, Dodd ME, Zhong X, Bollag WB.

J Dermatol Sci. 2010 Oct;60(1):29-39. doi: 10.1016/j.jdermsci.2010.07.015. Epub 2010 Aug 10.


Regulation of protein kinase D during differentiation and proliferation of primary mouse keratinocytes.

Ernest Dodd M, Ristich VL, Ray S, Lober RM, Bollag WB.

J Invest Dermatol. 2005 Aug;125(2):294-306.


Protein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytes.

Jadali A, Ghazizadeh S.

J Biol Chem. 2010 Jul 23;285(30):23387-97. doi: 10.1074/jbc.M110.105619. Epub 2010 May 12.


Activation of epidermal akt by diverse mouse skin tumor promoters.

Lu J, Rho O, Wilker E, Beltran L, Digiovanni J.

Mol Cancer Res. 2007 Dec;5(12):1342-52. doi: 10.1158/1541-7786.MCR-07-0115.


Sustained phospholipase D activation is associated with keratinocyte differentiation.

Jung EM, Betancourt-Calle S, Mann-Blakeney R, Griner RD, Bollinger Bollag W.

Carcinogenesis. 1999 Apr;20(4):569-76.


Protein kinase D1 deficiency promotes differentiation in epidermal keratinocytes.

Choudhary V, Olala LO, Kaddour-Djebbar I, Helwa I, Bollag WB.

J Dermatol Sci. 2014 Dec;76(3):186-95. doi: 10.1016/j.jdermsci.2014.09.007. Epub 2014 Oct 2.


PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents.

Adhikary G, Chew YC, Reece EA, Eckert RL.

J Invest Dermatol. 2010 Aug;130(8):2017-30. doi: 10.1038/jid.2010.108. Epub 2010 May 6.


Opposing growth regulatory roles of protein kinase D isoforms in human keratinocytes.

Ryvkin V, Rashel M, Gaddapara T, Ghazizadeh S.

J Biol Chem. 2015 Apr 24;290(17):11199-208. doi: 10.1074/jbc.M115.643742. Epub 2015 Mar 23.


Overexpression of connexin26 in the basal keratinocytes reduces sensitivity to tumor promoter TPA.

Wang X, Ramirez A, Budunova I.

Exp Dermatol. 2010 Jul 1;19(7):633-40. doi: 10.1111/j.1600-0625.2009.01013.x. Epub 2009 Dec 7.


Protein kinase D distribution in normal human epidermis, basal cell carcinoma and psoriasis.

Ristich VL, Bowman PH, Dodd ME, Bollag WB.

Br J Dermatol. 2006 Apr;154(4):586-93.


Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin.

Kim S, Hong I, Hwang JS, Choi JK, Rho HS, Kim DH, Chang I, Lee SH, Lee MO, Hwang JS.

Mol Med. 2006 Jan-Mar;12(1-3):17-24.


Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis.

Chan KS, Carbajal S, Kiguchi K, Clifford J, Sano S, DiGiovanni J.

Cancer Res. 2004 Apr 1;64(7):2382-9.


Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo.

Goto M, Kadoshima-Yamaoka K, Murakawa M, Yoshioka R, Tanaka Y, Inoue H, Murafuji H, Kanki S, Hayashi Y, Nagahira K, Ogata A, Nakatsuka T, Fukuda Y.

Eur J Pharmacol. 2010 May 10;633(1-3):93-7. doi: 10.1016/j.ejphar.2010.01.024. Epub 2010 Feb 2.


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