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Items: 1 to 20 of 90

1.

Adenoviral E4orf3 and E4orf6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo.

Liikanen I, Dias JD, Nokisalmi P, Sloniecka M, Kangasniemi L, Rajecki M, Dobner T, Tenhunen M, Kanerva A, Pesonen S, Ahtiainen L, Hemminki A.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1201-9. doi: 10.1016/j.ijrobp.2010.05.037. Epub 2010 Sep 9.

PMID:
20832189
2.

Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins.

Stracker TH, Lee DV, Carson CT, Araujo FD, Ornelles DA, Weitzman MD.

J Virol. 2005 Jun;79(11):6664-73.

3.

The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner.

Hart LS, Yannone SM, Naczki C, Orlando JS, Waters SB, Akman SA, Chen DJ, Ornelles D, Koumenis C.

J Biol Chem. 2005 Jan 14;280(2):1474-81. Epub 2004 Oct 26.

4.

The adenovirus E1b55K/E4orf6 complex induces degradation of the Bloom helicase during infection.

Orazio NI, Naeger CM, Karlseder J, Weitzman MD.

J Virol. 2011 Feb;85(4):1887-92. doi: 10.1128/JVI.02134-10. Epub 2010 Dec 1.

5.

Radiation-induced upregulation of gene expression from adenoviral vectors mediated by DNA damage repair and regulation.

Nokisalmi P, Rajecki M, Pesonen S, Escutenaire S, Soliymani R, Tenhunen M, Ahtiainen L, Hemminki A.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):376-84. doi: 10.1016/j.ijrobp.2011.06.1973. Epub 2011 Oct 20.

PMID:
22019240
6.

Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates.

Schwartz RA, Lakdawala SS, Eshleman HD, Russell MR, Carson CT, Weitzman MD.

J Virol. 2008 Sep;82(18):9043-55. doi: 10.1128/JVI.00925-08. Epub 2008 Jul 9.

7.

Transforming potential of the adenovirus type 5 E4orf3 protein.

Nevels M, Täuber B, Kremmer E, Spruss T, Wolf H, Dobner T.

J Virol. 1999 Feb;73(2):1591-600.

8.

The adenoviral E4orf6 protein induces atypical apoptosis in response to DNA damage.

Hart LS, Ornelles D, Koumenis C.

J Biol Chem. 2007 Mar 2;282(9):6061-7. Epub 2006 Dec 15.

9.

Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation.

Lakdawala SS, Schwartz RA, Ferenchak K, Carson CT, McSharry BP, Wilkinson GW, Weitzman MD.

J Virol. 2008 Sep;82(17):8362-72. doi: 10.1128/JVI.00900-08. Epub 2008 Jun 18.

10.

Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein.

König C, Roth J, Dobbelstein M.

J Virol. 1999 Mar;73(3):2253-62.

11.

Role of E1B55K in E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes.

Cheng CY, Gilson T, Wimmer P, Schreiner S, Ketner G, Dobner T, Branton PE, Blanchette P.

J Virol. 2013 Jun;87(11):6232-45. doi: 10.1128/JVI.00384-13. Epub 2013 Mar 27.

12.

The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity.

Cheng CY, Gilson T, Dallaire F, Ketner G, Branton PE, Blanchette P.

J Virol. 2011 Jan;85(2):765-75. doi: 10.1128/JVI.01890-10. Epub 2010 Nov 10. Erratum in: J Virol. 2011 May;85(9):4632.

13.

Adenovirus E4orf3 targets transcriptional intermediary factor 1γ for proteasome-dependent degradation during infection.

Forrester NA, Patel RN, Speiseder T, Groitl P, Sedgwick GG, Shimwell NJ, Seed RI, Catnaigh PÓ, McCabe CJ, Stewart GS, Dobner T, Grand RJ, Martin A, Turnell AS.

J Virol. 2012 Mar;86(6):3167-79. doi: 10.1128/JVI.06583-11. Epub 2011 Dec 28.

14.

Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex.

Querido E, Morrison MR, Chu-Pham-Dang H, Thirlwell SW, Boivin D, Branton PE.

J Virol. 2001 Jan;75(2):699-709. Erratum in: J Virol 2001 Mar;75(5):2508. Morisson MR [corrected to Morrison MR].

15.

Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells.

Collis SJ, Ketner GW, Hicks JL, Nelson WG, Demarzo AM, Deweese TL.

Int J Radiat Biol. 2003 Jan;79(1):53-60.

PMID:
12556331
16.

Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex.

Dallaire F, Blanchette P, Groitl P, Dobner T, Branton PE.

J Virol. 2009 Jun;83(11):5329-38. doi: 10.1128/JVI.00089-09. Epub 2009 Mar 18.

17.

Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes.

Araujo FD, Stracker TH, Carson CT, Lee DV, Weitzman MD.

J Virol. 2005 Sep;79(17):11382-91.

18.

The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication.

Schwartz RA, Palacios JA, Cassell GD, Adam S, Giacca M, Weitzman MD.

J Virol. 2007 Dec;81(23):12936-45. Epub 2007 Sep 26.

19.
20.

Half brain irradiation in a murine model of breast cancer brain metastasis: magnetic resonance imaging and histological assessments of dose-response.

Zarghami N, Murrell DH, Jensen MD, Dick FA, Chambers AF, Foster PJ, Wong E.

Radiat Oncol. 2018 Jun 1;13(1):104. doi: 10.1186/s13014-018-1028-8.

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