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Items: 1 to 20 of 316

1.

Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat.

Raz L, Zhang QG, Zhou CF, Han D, Gulati P, Yang LC, Yang F, Wang RM, Brann DW.

PLoS One. 2010 Sep 7;5(9):e12606. doi: 10.1371/journal.pone.0012606.

2.

CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia.

Kim GS, Jung JE, Niizuma K, Chan PH.

J Neurosci. 2009 Nov 25;29(47):14779-89. doi: 10.1523/JNEUROSCI.4161-09.2009.

3.

Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury.

Zhang QG, Laird MD, Han D, Nguyen K, Scott E, Dong Y, Dhandapani KM, Brann DW.

PLoS One. 2012;7(4):e34504. doi: 10.1371/journal.pone.0034504. Epub 2012 Apr 2.

4.

Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia.

Zhang QG, Wang R, Han D, Dong Y, Brann DW.

Brain Res. 2009 Apr 10;1265:138-47. doi: 10.1016/j.brainres.2009.01.033. Epub 2009 Jan 30.

5.

NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke.

Kahles T, Luedike P, Endres M, Galla HJ, Steinmetz H, Busse R, Neumann-Haefelin T, Brandes RP.

Stroke. 2007 Nov;38(11):3000-6. Epub 2007 Oct 4.

6.

NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus.

Kawakami-Mori F, Shimosawa T, Mu S, Wang H, Ogura S, Yatomi Y, Fujita T.

Am J Physiol Endocrinol Metab. 2012 Feb 15;302(4):E425-32. doi: 10.1152/ajpendo.00227.2011. Epub 2011 Nov 22.

7.

Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus.

Wang Q, Tompkins KD, Simonyi A, Korthuis RJ, Sun AY, Sun GY.

Brain Res. 2006 May 23;1090(1):182-9. Epub 2006 May 2.

PMID:
16650838
8.

NADPH oxidase-derived production of reactive oxygen species is involved in learning and memory impairments in 16-month-old female rats.

Kan H, Hu W, Wang Y, Wu W, Yin Y, Liang Y, Wang C, Huang D, Li W.

Mol Med Rep. 2015 Sep;12(3):4546-53. doi: 10.3892/mmr.2015.3894. Epub 2015 Jun 8.

PMID:
26058943
9.

Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2.

Meng S, Su Z, Liu Z, Wang N, Wang Z.

Neuroscience. 2015 Oct 15;306:100-14. doi: 10.1016/j.neuroscience.2015.08.014. Epub 2015 Aug 20.

PMID:
26299339
10.

Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways.

Ma J, Wang Y, Zheng D, Wei M, Xu H, Peng T.

Cardiovasc Res. 2013 Jan 1;97(1):77-87. doi: 10.1093/cvr/cvs309. Epub 2012 Oct 1.

PMID:
23027656
11.

Acupuncture elicits neuroprotective effect by inhibiting NAPDH oxidase-mediated reactive oxygen species production in cerebral ischaemia.

Shi GX, Wang XR, Yan CQ, He T, Yang JW, Zeng XH, Xu Q, Zhu W, Du SQ, Liu CZ.

Sci Rep. 2015 Dec 10;5:17981. doi: 10.1038/srep17981.

12.

NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke.

Miller AA, Dusting GJ, Roulston CL, Sobey CG.

Brain Res. 2006 Sep 21;1111(1):111-6. Epub 2006 Jul 31.

PMID:
16879806
13.

Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo.

Ozaki M, Deshpande SS, Angkeow P, Bellan J, Lowenstein CJ, Dinauer MC, Goldschmidt-Clermont PJ, Irani K.

FASEB J. 2000 Feb;14(2):418-29.

PMID:
10657998
14.

Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: role of NADPH oxidase-derived ROS.

Wang Q, Sun AY, Simonyi A, Kalogeris TJ, Miller DK, Sun GY, Korthuis RJ.

Free Radic Biol Med. 2007 Oct 1;43(7):1048-60. Epub 2007 Jul 4.

15.

Electroacupuncture pretreatment inhibits NADPH oxidase-mediated oxidative stress in diabetic mice with cerebral ischemia.

Guo F, Song W, Jiang T, Liu L, Wang F, Zhong H, Yin H, Wang Q, Xiong L.

Brain Res. 2014 Jul 21;1573:84-91. doi: 10.1016/j.brainres.2014.05.020. Epub 2014 May 20.

PMID:
24854123
16.

Interrupted reperfusion reduces the activation of NADPH oxidase after cerebral I/R injury.

Shen J, Bai XY, Qin Y, Jin WW, Zhou JY, Zhou JP, Yan YG, Wang Q, Bruce IC, Chen JH, Xia Q.

Free Radic Biol Med. 2011 Jun 15;50(12):1780-6. doi: 10.1016/j.freeradbiomed.2011.03.028. Epub 2011 Mar 31.

PMID:
21458562
17.

Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: role of neuronal NADPH oxidase.

Park KW, Jin BK.

J Neurosci Res. 2008 Apr;86(5):1053-63. doi: 10.1002/jnr.21571.

PMID:
18183616
18.

Knockdown of glucose-6-phosphate dehydrogenase (G6PD) following cerebral ischemic reperfusion: the pros and cons.

Zhao G, Zhao Y, Wang X, Xu Y.

Neurochem Int. 2012 Jul;61(2):146-55. doi: 10.1016/j.neuint.2012.05.003. Epub 2012 May 8.

PMID:
22580330
19.
20.

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

Subasinghe W, Syed I, Kowluru A.

Am J Physiol Regul Integr Comp Physiol. 2011 Jan;300(1):R12-20. doi: 10.1152/ajpregu.00421.2010. Epub 2010 Oct 13.

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