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Items: 1 to 20 of 156

1.

Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection.

Hedlund E, Karlsson M, Osborn T, Ludwig W, Isacson O.

Brain. 2010 Aug;133(Pt 8):2313-30. doi: 10.1093/brain/awq167.

2.

Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis.

Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo SW, Valori CF, Cox L, Sharrack B, Wharton SB, Ince PG, Shaw PJ, Azzouz M.

Brain. 2011 Feb;134(Pt 2):506-17. doi: 10.1093/brain/awq345. Epub 2011 Jan 12.

3.

Calcitonin gene-related peptide expression levels predict motor neuron vulnerability in the superoxide dismutase 1-G93A mouse model of amyotrophic lateral sclerosis.

Ringer C, Weihe E, Schütz B.

Neurobiol Dis. 2012 Jan;45(1):547-54. doi: 10.1016/j.nbd.2011.09.011. Epub 2011 Sep 21.

PMID:
21964254
4.

Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.

Vargas MR, Pehar M, Díaz-Amarilla PJ, Beckman JS, Barbeito L.

J Neurosci Res. 2008 Dec;86(16):3515-25. doi: 10.1002/jnr.21797.

5.

A potential role for the p75 low-affinity neurotrophin receptor in spinal motor neuron degeneration in murine and human amyotrophic lateral sclerosis.

Lowry KS, Murray SS, McLean CA, Talman P, Mathers S, Lopes EC, Cheema SS.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2001 Sep;2(3):127-34.

PMID:
11771768
6.

Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G⁹³A transgenic ALS mice.

Ozdinler PH, Benn S, Yamamoto TH, Güzel M, Brown RH Jr, Macklis JD.

J Neurosci. 2011 Mar 16;31(11):4166-77. doi: 10.1523/JNEUROSCI.4184-10.2011.

7.

Degeneration of respiratory motor neurons in the SOD1 G93A transgenic rat model of ALS.

Lladó J, Haenggeli C, Pardo A, Wong V, Benson L, Coccia C, Rothstein JD, Shefner JM, Maragakis NJ.

Neurobiol Dis. 2006 Jan;21(1):110-8. Epub 2005 Aug 9.

PMID:
16084734
8.

Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo.

Chi L, Ke Y, Luo C, Gozal D, Liu R.

Neuroscience. 2007 Feb 9;144(3):991-1003. Epub 2006 Dec 5.

9.

Activation transcription factor-3 activation and the development of spinal cord degeneration in a rat model of amyotrophic lateral sclerosis.

Malaspina A, Ngoh SF, Ward RE, Hall JC, Tai FW, Yip PK, Jones C, Jokic N, Averill SA, Michael-Titus AT, Priestley JV.

Neuroscience. 2010 Aug 25;169(2):812-27. doi: 10.1016/j.neuroscience.2010.04.053. Epub 2010 May 12.

PMID:
20470869
11.

In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient.

Niessen HG, Angenstein F, Sander K, Kunz WS, Teuchert M, Ludolph AC, Heinze HJ, Scheich H, Vielhaber S.

Exp Neurol. 2006 Oct;201(2):293-300. Epub 2006 Jun 5.

PMID:
16740261
12.

Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration.

Lunn JS, Sakowski SA, Kim B, Rosenberg AA, Feldman EL.

Dev Neurobiol. 2009 Nov;69(13):871-84. doi: 10.1002/dneu.20747.

13.

Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age.

Perrin FE, Boisset G, Lathuilière A, Kato AC.

J Neurochem. 2006 Sep;98(6):1959-72. Epub 2006 Jul 11.

14.

Lack of changes in the PI3K/AKT survival pathway in the spinal cord motor neurons of a mouse model of familial amyotrophic lateral sclerosis.

Peviani M, Cheroni C, Troglio F, Quarto M, Pelicci G, Bendotti C.

Mol Cell Neurosci. 2007 Apr;34(4):592-602. Epub 2007 Jan 11.

PMID:
17303436
15.

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis.

Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estévez AG, Barbeito L.

J Neurochem. 2004 Apr;89(2):464-73.

16.

Differential vulnerability of cranial motoneurons in mouse models with motor neuron degeneration.

Haenggeli C, Kato AC.

Neurosci Lett. 2002 Dec 19;335(1):39-43.

PMID:
12457737
17.

GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis.

Carunchio I, Mollinari C, Pieri M, Merlo D, Zona C.

Eur J Neurosci. 2008 Oct;28(7):1275-85. doi: 10.1111/j.1460-9568.2008.06436.x.

PMID:
18973555
18.

Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival.

Vargas MR, Pehar M, Cassina P, Martínez-Palma L, Thompson JA, Beckman JS, Barbeito L.

J Biol Chem. 2005 Jul 8;280(27):25571-9. Epub 2005 May 3.

19.

Retinoid receptors in chronic degeneration of the spinal cord: observations in a rat model of amyotrophic lateral sclerosis.

Jokic N, Ling YY, Ward RE, Michael-Titus AT, Priestley JV, Malaspina A.

J Neurochem. 2007 Dec;103(5):1821-33. Epub 2007 Sep 13.

20.

GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS.

Suzuki M, McHugh J, Tork C, Shelley B, Klein SM, Aebischer P, Svendsen CN.

PLoS One. 2007 Aug 1;2(8):e689.

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