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Items: 1 to 20 of 109

1.

Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures.

Dzhala VI, Kuchibhotla KV, Glykys JC, Kahle KT, Swiercz WB, Feng G, Kuner T, Augustine GJ, Bacskai BJ, Staley KJ.

J Neurosci. 2010 Sep 1;30(35):11745-61. doi: 10.1523/JNEUROSCI.1769-10.2010.

2.

Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.

Dzhala VI, Brumback AC, Staley KJ.

Ann Neurol. 2008 Feb;63(2):222-35.

PMID:
17918265
3.

The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures.

Kahle KT, Staley KJ.

Neurosurg Focus. 2008 Sep;25(3):E22. doi: 10.3171/FOC/2008/25/9/E22. Review.

PMID:
18759624
4.

NKCC1 transporter facilitates seizures in the developing brain.

Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ.

Nat Med. 2005 Nov;11(11):1205-13. Epub 2005 Oct 9.

PMID:
16227993
5.

Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABA(A) signaling in neonatal neurons.

Brumback AC, Staley KJ.

J Neurosci. 2008 Feb 6;28(6):1301-12. doi: 10.1523/JNEUROSCI.3378-07.2008.

6.

Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses.

Schöbel N, Radtke D, Lübbert M, Gisselmann G, Lehmann R, Cichy A, Schreiner BS, Altmüller J, Spector AC, Spehr J, Hatt H, Wetzel CH.

PLoS One. 2012;7(11):e48005. doi: 10.1371/journal.pone.0048005. Epub 2012 Nov 8.

7.

Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures.

Glykys J, Dzhala VI, Kuchibhotla KV, Feng G, Kuner T, Augustine G, Bacskai BJ, Staley KJ.

Neuron. 2009 Sep 10;63(5):657-72. doi: 10.1016/j.neuron.2009.08.022.

8.

Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.

Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry G, Jensen FE.

PLoS One. 2013;8(3):e57148. doi: 10.1371/journal.pone.0057148. Epub 2013 Mar 11. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/48a011e6-e4d0-4706-9a28-857eba8cfb31. Berry, Gerard [corrected to Berry, Gerard T].

9.

NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.

Zhu L, Polley N, Mathews GC, Delpire E.

Epilepsy Res. 2008 May;79(2-3):201-12. doi: 10.1016/j.eplepsyres.2008.02.005. Epub 2008 Apr 3.

10.

Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.

Nardou R, Yamamoto S, Chazal G, Bhar A, Ferrand N, Dulac O, Ben-Ari Y, Khalilov I.

Brain. 2011 Apr;134(Pt 4):987-1002. doi: 10.1093/brain/awr041. Epub 2011 Mar 23.

PMID:
21436113
11.

Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis.

Dzhala V, Staley KJ.

CNS Neurosci Ther. 2015 Feb;21(2):173-80. doi: 10.1111/cns.12369. Epub 2014 Dec 12.

12.

Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.

Sung KW, Kirby M, McDonald MP, Lovinger DM, Delpire E.

J Neurosci. 2000 Oct 15;20(20):7531-8.

13.

Kinetic properties of Cl uptake mediated by Na+-dependent K+-2Cl cotransport in immature rat neocortical neurons.

Achilles K, Okabe A, Ikeda M, Shimizu-Okabe C, Yamada J, Fukuda A, Luhmann HJ, Kilb W.

J Neurosci. 2007 Aug 8;27(32):8616-27.

14.

GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy.

Koyama R, Tao K, Sasaki T, Ichikawa J, Miyamoto D, Muramatsu R, Matsuki N, Ikegaya Y.

Nat Med. 2012 Aug;18(8):1271-8. doi: 10.1038/nm.2850. Epub 2012 Jul 15.

PMID:
22797810
15.
16.

The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia.

Pond BB, Berglund K, Kuner T, Feng G, Augustine GJ, Schwartz-Bloom RD.

J Neurosci. 2006 Feb 1;26(5):1396-406.

17.

Molecular and functional expression of cation-chloride cotransporters in dorsal root ganglion neurons during postnatal maturation.

Mao S, Garzon-Muvdi T, Di Fulvio M, Chen Y, Delpire E, Alvarez FJ, Alvarez-Leefmans FJ.

J Neurophysiol. 2012 Aug 1;108(3):834-52. doi: 10.1152/jn.00970.2011. Epub 2012 Mar 28.

18.

Both NKCC1 and anion exchangers contribute to Cl⁻ accumulation in postnatal forebrain neuronal progenitors.

Sun L, Yu Z, Wang W, Liu X.

Eur J Neurosci. 2012 Mar;35(5):661-72. doi: 10.1111/j.1460-9568.2012.08007.x.

PMID:
22390178
19.

Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy.

Brandt C, Nozadze M, Heuchert N, Rattka M, Löscher W.

J Neurosci. 2010 Jun 23;30(25):8602-12. doi: 10.1523/JNEUROSCI.0633-10.2010.

20.

Cl- uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1.

Yamada J, Okabe A, Toyoda H, Kilb W, Luhmann HJ, Fukuda A.

J Physiol. 2004 Jun 15;557(Pt 3):829-41. Epub 2004 Apr 16.

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