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Items: 1 to 20 of 111

1.

Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism.

Alvarado JJ, Betts L, Moroco JA, Smithgall TE, Yeh JI.

J Biol Chem. 2010 Nov 12;285(46):35455-61. doi: 10.1074/jbc.M110.145102.

2.

Activation of the Src family kinase Hck without SH3-linker release.

Lerner EC, Trible RP, Schiavone AP, Hochrein JM, Engen JR, Smithgall TE.

J Biol Chem. 2005 Dec 9;280(49):40832-7.

3.

Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.

Alvarado JJ, Tarafdar S, Yeh JI, Smithgall TE.

J Biol Chem. 2014 Oct 10;289(41):28539-53. doi: 10.1074/jbc.M114.600031.

4.

Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase.

Meiselbach H, Sticht H.

J Mol Model. 2011 Aug;17(8):1927-34. doi: 10.1007/s00894-010-0897-z.

PMID:
21110053
5.

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions.

Williams JC, Weijland A, Gonfloni S, Thompson A, Courtneidge SA, Superti-Furga G, Wierenga RK.

J Mol Biol. 1997 Dec 19;274(5):757-75.

PMID:
9405157
6.

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.

Moarefi I, LaFevre-Bernt M, Sicheri F, Huse M, Lee CH, Kuriyan J, Miller WT.

Nature. 1997 Feb 13;385(6617):650-3.

PMID:
9024665
7.

Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.

Jung J, Byeon IJ, Ahn J, Gronenborn AM.

Proteins. 2011 May;79(5):1609-22. doi: 10.1002/prot.22986.

8.

The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

Gonfloni S, Williams JC, Hattula K, Weijland A, Wierenga RK, Superti-Furga G.

EMBO J. 1997 Dec 15;16(24):7261-71.

9.

Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue.

LaFevre-Bernt M, Sicheri F, Pico A, Porter M, Kuriyan J, Miller WT.

J Biol Chem. 1998 Nov 27;273(48):32129-34.

10.

HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.

Trible RP, Emert-Sedlak L, Smithgall TE.

J Biol Chem. 2006 Sep 15;281(37):27029-38.

11.
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13.

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.

Arold S, O'Brien R, Franken P, Strub MP, Hoh F, Dumas C, Ladbury JE.

Biochemistry. 1998 Oct 20;37(42):14683-91.

PMID:
9778343
14.

The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct.

Gosser YQ, Zheng J, Overduin M, Mayer BJ, Cowburn D.

Structure. 1995 Oct 15;3(10):1075-86.

15.

Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X.

Shi X, Opi S, Lugari A, Restouin A, Coursindel T, Parrot I, Perez J, Madore E, Zimmermann P, Corbeil J, Huang M, Arold ST, Collette Y, Morelli X.

Biochem J. 2010 Oct 1;431(1):93-102. doi: 10.1042/BJ20100314.

PMID:
20670214
16.

Solution structure of the human Hck SH3 domain and identification of its ligand binding site.

Horita DA, Baldisseri DM, Zhang W, Altieri AS, Smithgall TE, Gmeiner WH, Byrd RA.

J Mol Biol. 1998 Apr 24;278(1):253-65.

PMID:
9571048
17.

Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through β-sheet formation.

Wybenga-Groot LE, McGlade CJ.

Cell Signal. 2013 Dec;25(12):2702-8. doi: 10.1016/j.cellsig.2013.08.040.

PMID:
24018043
18.

Crystal structure of the Src family tyrosine kinase Hck.

Sicheri F, Moarefi I, Kuriyan J.

Nature. 1997 Feb 13;385(6617):602-9.

PMID:
9024658
19.

Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.

Briggs SD, Lerner EC, Smithgall TE.

Biochemistry. 2000 Jan 25;39(3):489-95.

PMID:
10642173
20.

SH2-catalytic domain linker heterogeneity influences allosteric coupling across the SFK family.

Register AC, Leonard SE, Maly DJ.

Biochemistry. 2014 Nov 11;53(44):6910-23. doi: 10.1021/bi5008194.

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