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Items: 1 to 20 of 105

1.

The autoimmune TCR-Ob.2F3 can bind to MBP85-99/HLA-DR2 having an unconventional mode as in TCR-Ob.1A12.

Kato Z, Stern JN, Nakamura HK, Miyashita N, Kuwata K, Kondo N, Strominger JL.

Mol Immunol. 2010 Nov-Dec;48(1-3):314-20. doi: 10.1016/j.molimm.2010.07.010.

PMID:
20810170
2.

Positioning of autoimmune TCR-Ob.2F3 and TCR-Ob.3D1 on the MBP85-99/HLA-DR2 complex.

Kato Z, Stern JN, Nakamura HK, Kuwata K, Kondo N, Strominger JL.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15523-8. doi: 10.1073/pnas.0807338105. Epub 2008 Sep 29.

3.
4.

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.

Madsen LS, Andersson EC, Jansson L, krogsgaard M, Andersen CB, Engberg J, Strominger JL, Svejgaard A, Hjorth JP, Holmdahl R, Wucherpfennig KW, Fugger L.

Nat Genet. 1999 Nov;23(3):343-7.

PMID:
10610182
5.
6.
7.

Design, engineering, and production of human recombinant t cell receptor ligands derived from human leukocyte antigen DR2.

Chang JW, Mechling DE, B├Ąchinger HP, Burrows GG.

J Biol Chem. 2001 Jun 29;276(26):24170-6. Epub 2001 Apr 23.

8.

Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: implications for the initiation of the autoimmune response in multiple sclerosis.

Zhang X, Tang Y, Sujkowska D, Wang J, Ramgolam V, Sospedra M, Adams J, Martin R, Pinilla C, Markovic-Plese S.

Eur J Immunol. 2008 May;38(5):1297-309. doi: 10.1002/eji.200737519.

9.

Structural features of autoreactive TCR that determine the degree of degeneracy in peptide recognition.

Hausmann S, Martin M, Gauthier L, Wucherpfennig KW.

J Immunol. 1999 Jan 1;162(1):338-44.

10.

Structural basis of molecular mimicry.

Wucherpfennig KW.

J Autoimmun. 2001 May;16(3):293-302. Review.

PMID:
11334495
11.

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones.

Wucherpfennig KW, Sette A, Southwood S, Oseroff C, Matsui M, Strominger JL, Hafler DA.

J Exp Med. 1994 Jan 1;179(1):279-90.

12.

T cell receptor crossreactivity as a general property of T cell recognition.

Wucherpfennig KW.

Mol Immunol. 2004 Feb;40(14-15):1009-17. Review.

PMID:
15036904
13.

Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells.

Appel H, Gauthier L, Pyrdol J, Wucherpfennig KW.

J Biol Chem. 2000 Jan 7;275(1):312-21.

14.

Cross-reactive TCR responses to self antigens presented by different MHC class II molecules.

Mycko MP, Waldner H, Anderson DE, Bourcier KD, Wucherpfennig KW, Kuchroo VK, Hafler DA.

J Immunol. 2004 Aug 1;173(3):1689-98.

15.

Restricted TCR Valpha gene rearrangements in T cells recognizing an immunodominant peptide of myelin basic protein in DR2 patients with multiple sclerosis.

Zang YC, Kozovska M, Aebischer I, Li S, Boehme S, Crowe P, Rivera VM, Zhang JZ.

Int Immunol. 1998 Jul;10(7):991-8.

PMID:
9701037
16.

Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.

Li Y, Huang Y, Lue J, Quandt JA, Martin R, Mariuzza RA.

EMBO J. 2005 Sep 7;24(17):2968-79. Epub 2005 Aug 4.

18.

Predominant and stable T cell responses to regions of myelin basic protein can be detected in individual patients with multiple sclerosis.

Salvetti M, Ristori G, D'Amato M, Buttinelli C, Falcone M, Fieschi C, Wekerle H, Pozzilli C.

Eur J Immunol. 1993 Jun;23(6):1232-9.

PMID:
7684682
19.

Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99).

Vergelli M, Hemmer B, Utz U, Vogt A, Kalbus M, Tranquill L, Conlon P, Ling N, Steinman L, McFarland HF, Martin R.

Eur J Immunol. 1996 Nov;26(11):2624-34.

PMID:
8921948
20.

Structural analysis of two HLA-DR-presented autoantigenic epitopes: crucial role of peripheral but not central peptide residues for T-cell receptor recognition.

De Oliveira DB, Harfouch-Hammoud E, Otto H, Papandreou NA, Stern LJ, Cohen H, Boehm BO, Bach J, Caillat-Zucman S, Walk T, Jung G, Eliopoulos E, Papadopoulos GK, van Endert PM.

Mol Immunol. 2000 Oct;37(14):813-25.

PMID:
11257303

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