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Items: 1 to 20 of 104

1.

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells.

Molyneux G, Geyer FC, Magnay FA, McCarthy A, Kendrick H, Natrajan R, Mackay A, Grigoriadis A, Tutt A, Ashworth A, Reis-Filho JS, Smalley MJ.

Cell Stem Cell. 2010 Sep 3;7(3):403-17. doi: 10.1016/j.stem.2010.07.010.

2.

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.

Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab., Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ.

Nat Med. 2009 Aug;15(8):907-13. doi: 10.1038/nm.2000. Epub 2009 Aug 2.

PMID:
19648928
3.

The cell of origin of BRCA1 mutation-associated breast cancer: a cautionary tale of gene expression profiling.

Molyneux G, Smalley MJ.

J Mammary Gland Biol Neoplasia. 2011 Apr;16(1):51-5. doi: 10.1007/s10911-011-9202-8. Epub 2011 Feb 19. Review.

PMID:
21336547
4.

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

Liu X, Holstege H, van der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, van Vliet MH, Wessels LF, Peterse JL, Berns A, Jonkers J.

Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12111-6. Epub 2007 Jul 11.

5.

Cell fate takes a slug in BRCA1-associated breast cancer.

Lindeman GJ, Visvader JE.

Breast Cancer Res. 2011 Apr 6;13(2):306. doi: 10.1186/bcr2840.

6.

Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.

Gastaldi S, Sassi F, Accornero P, Torti D, Galimi F, Migliardi G, Molyneux G, Perera T, Comoglio PM, Boccaccio C, Smalley MJ, Bertotti A, Trusolino L.

Oncogene. 2013 Mar 14;32(11):1428-40. doi: 10.1038/onc.2012.154. Epub 2012 May 7.

PMID:
22562252
7.

Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation.

Bai F, Smith MD, Chan HL, Pei XH.

Oncogene. 2013 May 30;32(22):2715-25. doi: 10.1038/onc.2012.293. Epub 2012 Jul 9.

PMID:
22777348
8.

BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development.

Bai F, Chan HL, Scott A, Smith MD, Fan C, Herschkowitz JI, Perou CM, Livingstone AS, Robbins DJ, Capobianco AJ, Pei XH.

Cancer Res. 2014 Nov 1;74(21):6161-72. doi: 10.1158/0008-5472.CAN-14-1119. Epub 2014 Sep 19.

9.

The basal phenotype of BRCA1-related breast cancer: past, present and future.

Tischkowitz MD, Foulkes WD.

Cell Cycle. 2006 May;5(9):963-7. Epub 2006 May 1. Review.

PMID:
16687925
10.

BRCA1 regulates human mammary stem/progenitor cell fate.

Liu S, Ginestier C, Charafe-Jauffret E, Foco H, Kleer CG, Merajver SD, Dontu G, Wicha MS.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1680-5. doi: 10.1073/pnas.0711613105. Epub 2008 Jan 29.

11.

The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.

Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Gruvberger-Saal SK, Saal LH, Holm K, Hegardt C, Arason A, Fagerholm R, Persson C, Grabau D, Johnsson E, Lövgren K, Magnusson L, Heikkilä P, Agnarsson BA, Johannsson OT, Malmström P, Fernö M, Olsson H, Loman N, Nevanlinna H, Barkardottir RB, Borg Å.

Cancer Res. 2012 Aug 15;72(16):4028-36. Epub 2012 Jun 15.

13.

Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers.

Yan M, Shield-Artin K, Byrne D, Deb S, Waddell N; kConFab Investigators, kConFab., Haviv I, Fox SB.

BMC Cancer. 2015 Jul 8;15:506. doi: 10.1186/s12885-015-1522-4.

14.

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

Regan JL, Kendrick H, Magnay FA, Vafaizadeh V, Groner B, Smalley MJ.

Oncogene. 2012 Feb 16;31(7):869-83. doi: 10.1038/onc.2011.289. Epub 2011 Jul 18.

PMID:
21765473
15.

Basal-like breast cancers: the phenotypic disparity between the cancer-initiating cells and tumor histology.

Raouf A.

Breast Cancer Res. 2010;12(6):316. doi: 10.1186/bcr2764. Epub 2010 Dec 16.

16.

Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.

Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6124-9. doi: 10.1073/pnas.1203203109. Epub 2012 Mar 27.

17.

Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers.

Zvelebil M, Oliemuller E, Gao Q, Wansbury O, Mackay A, Kendrick H, Smalley MJ, Reis-Filho JS, Howard BA.

Breast Cancer Res. 2013 Mar 18;15(2):R25. doi: 10.1186/bcr3403.

18.

Expression of the stem cell marker ALDH1 in BRCA1 related breast cancer.

Heerma van Voss MR, van der Groep P, Bart J, van der Wall E, van Diest PJ.

Cell Oncol (Dordr). 2011 Feb;34(1):3-10. doi: 10.1007/s13402-010-0007-3. Epub 2011 Feb 19.

19.

The phenotypic spectrum of basal-like breast cancers: a critical appraisal.

Fadare O, Tavassoli FA.

Adv Anat Pathol. 2007 Sep;14(5):358-73. Review.

PMID:
17717437
20.

Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer.

Foulkes WD, Stefansson IM, Chappuis PO, Bégin LR, Goffin JR, Wong N, Trudel M, Akslen LA.

J Natl Cancer Inst. 2003 Oct 1;95(19):1482-5.

PMID:
14519755

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