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Items: 1 to 20 of 128

1.

Glucuronidation of racemic O-desmethyltramadol, the active metabolite of tramadol.

Lehtonen P, Sten T, Aitio O, Kurkela M, Vuorensola K, Finel M, Kostiainen R.

Eur J Pharm Sci. 2010 Nov 20;41(3-4):523-30. doi: 10.1016/j.ejps.2010.08.005. Epub 2010 Aug 24.

PMID:
20797434
2.

Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.

Court MH, Duan SX, Guillemette C, Journault K, Krishnaswamy S, Von Moltke LL, Greenblatt DJ.

Drug Metab Dispos. 2002 Nov;30(11):1257-65.

3.

Prominent but reverse stereoselectivity in propranolol glucuronidation by human UDP-glucuronosyltransferases 1A9 and 1A10.

Sten T, Qvisen S, Uutela P, Luukkanen L, Kostiainen R, Finel M.

Drug Metab Dispos. 2006 Sep;34(9):1488-94. Epub 2006 Jun 8.

4.

Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases.

Kuuranne T, Kurkela M, Thevis M, Schänzer W, Finel M, Kostiainen R.

Drug Metab Dispos. 2003 Sep;31(9):1117-24.

5.

Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases.

Sun D, Sharma AK, Dellinger RW, Blevins-Primeau AS, Balliet RM, Chen G, Boyiri T, Amin S, Lazarus P.

Drug Metab Dispos. 2007 Nov;35(11):2006-14. Epub 2007 Jul 30.

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Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2002 Jun;30(6):636-42.

9.

The role of human UDP-glucuronyltransferases on the formation of the methylenedioxymethamphetamine (ecstasy) phase II metabolites R- and S-3-methoxymethamphetamine 4-O-glucuronides.

Schwaninger AE, Meyer MR, Zapp J, Maurer HH.

Drug Metab Dispos. 2009 Nov;37(11):2212-20. doi: 10.1124/dmd.109.029215. Epub 2009 Aug 10.

10.

Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.

Hanioka N, Naito T, Narimatsu S.

Chemosphere. 2008 Dec;74(1):33-6. doi: 10.1016/j.chemosphere.2008.09.053. Epub 2008 Nov 5.

PMID:
18990428
11.

Determination of tramadol and O-desmethyltramadol in human plasma by high-performance liquid chromatography with mass spectrometry detection.

Vlase L, Leucuta SE, Imre S.

Talanta. 2008 May 30;75(4):1104-9. doi: 10.1016/j.talanta.2008.01.006. Epub 2008 Jan 16.

PMID:
18585190
12.

The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.

Alonen A, Finel M, Kostiainen R.

Biochem Pharmacol. 2008 Sep 15;76(6):763-72. doi: 10.1016/j.bcp.2008.07.006. Epub 2008 Jul 12.

PMID:
18674515
13.

N-glucuronidation of the platelet-derived growth factor receptor tyrosine kinase inhibitor 6,7-(dimethoxy-2,4-dihydroindeno[1,2-C]pyrazol-3-yl)-(3-fluoro-phenyl)-amine by human UDP-glucuronosyltransferases.

Yan Z, Caldwell GW, Gauthier D, Leo GC, Mei J, Ho CY, Jones WJ, Masucci JA, Tuman RW, Galemmo RA Jr, Johnson DL.

Drug Metab Dispos. 2006 May;34(5):748-55. Epub 2006 Feb 2.

14.

In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.

Tong Z, Li H, Goljer I, McConnell O, Chandrasekaran A.

Drug Metab Dispos. 2007 Dec;35(12):2203-10. Epub 2007 Sep 17.

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Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.

Ogura K, Ishikawa Y, Kaku T, Nishiyama T, Ohnuma T, Muro K, Hiratsuka A.

Biochem Pharmacol. 2006 Apr 28;71(9):1358-69. Epub 2006 Feb 14.

PMID:
16480962
19.

Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.

Innocenti F, Iyer L, Ramírez J, Green MD, Ratain MJ.

Drug Metab Dispos. 2001 May;29(5):686-92.

20.

Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases.

Jančová P, Siller M, Anzenbacherová E, Křen V, Anzenbacher P, Simánek V.

Xenobiotica. 2011 Sep;41(9):743-51. doi: 10.3109/00498254.2011.573017. Epub 2011 Apr 27.

PMID:
21524189

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