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Items: 1 to 20 of 117

1.

Calpastatin reduces toxicity of SOD1G93A in a culture model of amyotrophic lateral sclerosis.

Tradewell ML, Durham HD.

Neuroreport. 2010 Oct 27;21(15):976-9. doi: 10.1097/WNR.0b013e32833ddd45.

PMID:
20736867
2.

Calpastatin inhibits motor neuron death and increases survival of hSOD1(G93A) mice.

Rao MV, Campbell J, Palaniappan A, Kumar A, Nixon RA.

J Neurochem. 2016 Apr;137(2):253-65. doi: 10.1111/jnc.13536. Epub 2016 Mar 23.

3.

Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention.

Tradewell ML, Cooper LA, Minotti S, Durham HD.

Neurobiol Dis. 2011 Jun;42(3):265-75. doi: 10.1016/j.nbd.2011.01.016. Epub 2011 Feb 3.

PMID:
21296666
4.

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.

Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD.

Neurobiol Dis. 2001 Dec;8(6):933-41.

PMID:
11741389
5.

Zinc pre-treatment enhances NMDAR-mediated excitotoxicity in cultured cortical neurons from SOD1(G93A) mouse, a model of amyotrophic lateral sclerosis.

Nutini M, Frazzini V, Marini C, Spalloni A, Sensi SL, Longone P.

Neuropharmacology. 2011 Jun;60(7-8):1200-8. doi: 10.1016/j.neuropharm.2010.11.001. Epub 2010 Nov 5.

PMID:
21056589
6.

Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration.

Lunn JS, Sakowski SA, Kim B, Rosenberg AA, Feldman EL.

Dev Neurobiol. 2009 Nov;69(13):871-84. doi: 10.1002/dneu.20747.

7.

XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.

Wootz H, Hansson I, Korhonen L, Lindholm D.

Exp Cell Res. 2006 Jun 10;312(10):1890-8. Epub 2006 Mar 29.

PMID:
16566922
8.

MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis.

Zhang X, Chen S, Song L, Tang Y, Shen Y, Jia L, Le W.

Autophagy. 2014 Apr;10(4):588-602. doi: 10.4161/auto.27710. Epub 2014 Jan 15.

9.

c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis.

Katsumata R, Ishigaki S, Katsuno M, Kawai K, Sone J, Huang Z, Adachi H, Tanaka F, Urano F, Sobue G.

PLoS One. 2012;7(9):e46185. doi: 10.1371/journal.pone.0046185. Epub 2012 Sep 25.

10.

CAST your vote: is calpain inhibition the answer to ALS?

Wright AL, Vissel B.

J Neurochem. 2016 Apr;137(2):140-1. doi: 10.1111/jnc.13296. Epub 2016 Mar 23.

12.
13.

Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Novoselov SS, Mustill WJ, Gray AL, Dick JR, Kanuga N, Kalmar B, Greensmith L, Cheetham ME.

PLoS One. 2013 Aug 30;8(8):e73944. doi: 10.1371/journal.pone.0073944. eCollection 2013.

14.

The voltage-gated calcium channel blocker lomerizine is neuroprotective in motor neurons expressing mutant SOD1, but not TDP-43.

Tran LT, Gentil BJ, Sullivan KE, Durham HD.

J Neurochem. 2014 Aug;130(3):455-66. doi: 10.1111/jnc.12738. Epub 2014 May 9.

15.

Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis.

Cheroni C, Marino M, Tortarolo M, Veglianese P, De Biasi S, Fontana E, Zuccarello LV, Maynard CJ, Dantuma NP, Bendotti C.

Hum Mol Genet. 2009 Jan 1;18(1):82-96. doi: 10.1093/hmg/ddn319. Epub 2008 Sep 29.

17.

Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis.

Miquel E, Cassina A, Martínez-Palma L, Bolatto C, Trías E, Gandelman M, Radi R, Barbeito L, Cassina P.

PLoS One. 2012;7(4):e34776. doi: 10.1371/journal.pone.0034776. Epub 2012 Apr 3.

18.
19.

Insoluble mutant SOD1 is partly oligoubiquitinated in amyotrophic lateral sclerosis mice.

Basso M, Massignan T, Samengo G, Cheroni C, De Biasi S, Salmona M, Bendotti C, Bonetto V.

J Biol Chem. 2006 Nov 3;281(44):33325-35. Epub 2006 Aug 30.

20.

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

Crippa V, Sau D, Rusmini P, Boncoraglio A, Onesto E, Bolzoni E, Galbiati M, Fontana E, Marino M, Carra S, Bendotti C, De Biasi S, Poletti A.

Hum Mol Genet. 2010 Sep 1;19(17):3440-56. doi: 10.1093/hmg/ddq257. Epub 2010 Jun 22.

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