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Items: 1 to 20 of 124

1.

ChIP-Seq identification of weakly conserved heart enhancers.

Blow MJ, McCulley DJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Bristow J, Ren B, Black BL, Rubin EM, Visel A, Pennacchio LA.

Nat Genet. 2010 Sep;42(9):806-10. doi: 10.1038/ng.650. Epub 2010 Aug 22.

2.

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart.

He A, Kong SW, Ma Q, Pu WT.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5632-7. doi: 10.1073/pnas.1016959108. Epub 2011 Mar 17.

3.

ChIP-seq accurately predicts tissue-specific activity of enhancers.

Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Ren B, Rubin EM, Pennacchio LA.

Nature. 2009 Feb 12;457(7231):854-8. doi: 10.1038/nature07730.

4.

Regulation of Six1 expression by evolutionarily conserved enhancers in tetrapods.

Sato S, Ikeda K, Shioi G, Nakao K, Yajima H, Kawakami K.

Dev Biol. 2012 Aug 1;368(1):95-108. doi: 10.1016/j.ydbio.2012.05.023. Epub 2012 May 30.

5.

Mouse transgenesis identifies conserved functional enhancers and cis-regulatory motif in the vertebrate LIM homeobox gene Lhx2 locus.

Lee AP, Brenner S, Venkatesh B.

PLoS One. 2011;6(5):e20088. doi: 10.1371/journal.pone.0020088. Epub 2011 May 23.

6.

Integrating diverse datasets improves developmental enhancer prediction.

Erwin GD, Oksenberg N, Truty RM, Kostka D, Murphy KK, Ahituv N, Pollard KS, Capra JA.

PLoS Comput Biol. 2014 Jun 26;10(6):e1003677. doi: 10.1371/journal.pcbi.1003677. eCollection 2014 Jun.

7.

Evolutionary constraint on Otx2 neuroectoderm enhancers-deep conservation from skate to mouse and unique divergence in teleost.

Kurokawa D, Sakurai Y, Inoue A, Nakayama R, Takasaki N, Suda Y, Miyake T, Amemiya CT, Aizawa S.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19350-5. Epub 2006 Dec 11.

8.

Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention.

Hufton AL, Mathia S, Braun H, Georgi U, Lehrach H, Vingron M, Poustka AJ, Panopoulou G.

Genome Res. 2009 Nov;19(11):2036-51. doi: 10.1101/gr.093237.109. Epub 2009 Aug 24.

9.

Epigenomic model of cardiac enhancers with application to genome wide association studies.

Sahu AD, Aniba R, Chang YP, Hannenhalli S.

Pac Symp Biocomput. 2013:92-102.

10.

Variable evolutionary signatures at the heart of enhancers.

Hardison RC.

Nat Genet. 2010 Sep;42(9):734-5. doi: 10.1038/ng0910-734.

11.

Many human accelerated regions are developmental enhancers.

Capra JA, Erwin GD, McKinsey G, Rubenstein JL, Pollard KS.

Philos Trans R Soc Lond B Biol Sci. 2013 Nov 11;368(1632):20130025. doi: 10.1098/rstb.2013.0025. Print 2013 Dec 19.

12.
13.

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.

van den Boogaard M, Wong LY, Tessadori F, Bakker ML, Dreizehnter LK, Wakker V, Bezzina CR, 't Hoen PA, Bakkers J, Barnett P, Christoffels VM.

J Clin Invest. 2012 Jul;122(7):2519-30. doi: 10.1172/JCI62613. Epub 2012 Jun 18.

14.

The enhancer landscape during early neocortical development reveals patterns of dense regulation and co-option.

Wenger AM, Clarke SL, Notwell JH, Chung T, Tuteja G, Guturu H, Schaar BT, Bejerano G.

PLoS Genet. 2013 Aug;9(8):e1003728. doi: 10.1371/journal.pgen.1003728. Epub 2013 Aug 29.

15.

Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene.

Guth SI, Bösl MR, Sock E, Wegner M.

Int J Biochem Cell Biol. 2010 Mar;42(3):465-71. doi: 10.1016/j.biocel.2009.07.008. Epub 2009 Jul 26.

PMID:
19638316
16.

The Evolution of Bony Vertebrate Enhancers at Odds with Their Coding Sequence Landscape.

Yousaf A, Sohail Raza M, Ali Abbasi A.

Genome Biol Evol. 2015 Aug 6;7(8):2333-43. doi: 10.1093/gbe/evv146.

17.

A map of the cis-regulatory sequences in the mouse genome.

Shen Y, Yue F, McCleary DF, Ye Z, Edsall L, Kuan S, Wagner U, Dixon J, Lee L, Lobanenkov VV, Ren B.

Nature. 2012 Aug 2;488(7409):116-20. doi: 10.1038/nature11243.

18.

Ultraconservation identifies a small subset of extremely constrained developmental enhancers.

Visel A, Prabhakar S, Akiyama JA, Shoukry M, Lewis KD, Holt A, Plajzer-Frick I, Afzal V, Rubin EM, Pennacchio LA.

Nat Genet. 2008 Feb;40(2):158-60. doi: 10.1038/ng.2007.55. Epub 2008 Jan 6.

19.

Large-scale discovery of enhancers from human heart tissue.

May D, Blow MJ, Kaplan T, McCulley DJ, Jensen BC, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Afzal V, Simpson PC, Rubin EM, Black BL, Bristow J, Pennacchio LA, Visel A.

Nat Genet. 2011 Dec 4;44(1):89-93. doi: 10.1038/ng.1006.

20.

Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes.

Gorkin DU, Lee D, Reed X, Fletez-Brant C, Bessling SL, Loftus SK, Beer MA, Pavan WJ, McCallion AS.

Genome Res. 2012 Nov;22(11):2290-301. doi: 10.1101/gr.139360.112. Epub 2012 Sep 27.

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