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Items: 1 to 20 of 110

1.

Anti-tumor activity of splice-switching oligonucleotides.

Bauman JA, Li SD, Yang A, Huang L, Kole R.

Nucleic Acids Res. 2010 Dec;38(22):8348-56. doi: 10.1093/nar/gkq731.

2.

Pro-apoptotic effects of splice-switching oligonucleotides targeting Bcl-x pre-mRNA in human glioma cell lines.

Li Z, Li Q, Han L, Tian N, Liang Q, Li Y, Zhao X, Du C, Tian Y.

Oncol Rep. 2016 Feb;35(2):1013-9. doi: 10.3892/or.2015.4465.

PMID:
26718027
3.

Modulation of RNA splicing as a potential treatment for cancer.

Bauman JA, Kole R.

Bioeng Bugs. 2011 May-Jun;2(3):125-8.

4.

Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death.

Mercatante DR, Bortner CD, Cidlowski JA, Kole R.

J Biol Chem. 2001 May 11;276(19):16411-7.

PMID:
11278482
5.

The importance of Bcl-xL in the survival of human RPE cells.

Zhang N, Peairs JJ, Yang P, Tyrrell J, Roberts J, Kole R, Jaffe GJ.

Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3846-53.

PMID:
17652760
6.

Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.

Xiao Q, Ford AL, Xu J, Yan P, Lee KY, Gonzales E, West T, Holtzman DM, Lee JM.

J Neurosci. 2012 Sep 26;32(39):13587-96.

7.

Modification of alternative splicing of Bcl-x pre-mRNA in bladder cancer cells.

Zhu Z, Xing S, Cheng P, Zeng F, Lu G.

J Huazhong Univ Sci Technolog Med Sci. 2006;26(2):213-6.

PMID:
16850750
8.

Development of therapeutic splice-switching oligonucleotides.

Disterer P, Kryczka A, Liu Y, Badi YE, Wong JJ, Owen JS, Khoo B.

Hum Gene Ther. 2014 Jul;25(7):587-98. doi: 10.1089/hum.2013.234. Review.

9.

Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents.

Mercatante DR, Mohler JL, Kole R.

J Biol Chem. 2002 Dec 20;277(51):49374-82.

PMID:
12381725
10.

Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo.

Wilusz JE, Devanney SC, Caputi M.

Nucleic Acids Res. 2005 Nov 18;33(20):6547-54.

11.

RNA modulation, repair and remodeling by splice switching oligonucleotides.

Kole R, Williams T, Cohen L.

Acta Biochim Pol. 2004;51(2):373-8. Review.

12.

Antagonistic effects of the SRp30c protein and cryptic 5' splice sites on the alternative splicing of the apoptotic regulator Bcl-x.

Cloutier P, Toutant J, Shkreta L, Goekjian S, Revil T, Chabot B.

J Biol Chem. 2008 Aug 1;283(31):21315-24. doi: 10.1074/jbc.M800353200.

PMID:
18534987
13.

Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide.

Massiello A, Salas A, Pinkerman RL, Roddy P, Roesser JR, Chalfant CE.

J Biol Chem. 2004 Apr 16;279(16):15799-804.

PMID:
14734550
14.

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.

Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B.

Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11.

15.

Therapeutic potential of splice-switching oligonucleotides.

Bauman J, Jearawiriyapaisarn N, Kole R.

Oligonucleotides. 2009 Mar;19(1):1-13. doi: 10.1089/oli.2008.0161. Review.

16.

Engineering splicing factors with designed specificities.

Wang Y, Cheong CG, Hall TM, Wang Z.

Nat Methods. 2009 Nov;6(11):825-30. doi: 10.1038/nmeth.1379.

17.

Splice-switching antisense oligonucleotides as therapeutic drugs.

Havens MA, Hastings ML.

Nucleic Acids Res. 2016 Aug 19;44(14):6549-63. doi: 10.1093/nar/gkw533.

18.

Protein phosphatase 1 activation and alternative splicing of Bcl-X and Mcl-1 by EGCG + ibuprofen.

Kim MH.

J Cell Biochem. 2008 Jul 1;104(4):1491-9. doi: 10.1002/jcb.21725.

PMID:
18348186
19.

Design and evaluation of locked nucleic acid-based splice-switching oligonucleotides in vitro.

Shimo T, Tachibana K, Saito K, Yoshida T, Tomita E, Waki R, Yamamoto T, Doi T, Inoue T, Kawakami J, Obika S.

Nucleic Acids Res. 2014 Jul;42(12):8174-87. doi: 10.1093/nar/gku512.

20.

Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides.

Hemphill J, Liu Q, Uprety R, Samanta S, Tsang M, Juliano RL, Deiters A.

J Am Chem Soc. 2015 Mar 18;137(10):3656-62. doi: 10.1021/jacs.5b00580.

PMID:
25734836
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