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Items: 1 to 20 of 109

1.

The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity.

Pietrella D, Rachini A, Pandey N, Schild L, Netea M, Bistoni F, Hube B, Vecchiarelli A.

Infect Immun. 2010 Nov;78(11):4754-62. doi: 10.1128/IAI.00789-10. Epub 2010 Aug 16.

2.
3.

Secretory Aspartyl Proteinases Cause Vaginitis and Can Mediate Vaginitis Caused by Candida albicans in Mice.

Pericolini E, Gabrielli E, Amacker M, Kasper L, Roselletti E, Luciano E, Sabbatini S, Kaeser M, Moser C, Hube B, Vecchiarelli A, Cassone A.

MBio. 2015 Jun 2;6(3):e00724. doi: 10.1128/mBio.00724-15.

4.

Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome.

Pietrella D, Pandey N, Gabrielli E, Pericolini E, Perito S, Kasper L, Bistoni F, Cassone A, Hube B, Vecchiarelli A.

Eur J Immunol. 2013 Mar;43(3):679-92. doi: 10.1002/eji.201242691. Epub 2013 Jan 31.

5.

Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans.

Lermann U, Morschhäuser J.

Microbiology. 2008 Nov;154(Pt 11):3281-3295. doi: 10.1099/mic.0.2008/022525-0.

PMID:
18957582
6.

Induction of caspase-11 by aspartyl proteinases of Candida albicans and implication in promoting inflammatory response.

Gabrielli E, Pericolini E, Luciano E, Sabbatini S, Roselletti E, Perito S, Kasper L, Hube B, Vecchiarelli A.

Infect Immun. 2015 May;83(5):1940-8. doi: 10.1128/IAI.02895-14. Epub 2015 Feb 23.

7.

Enzymic characteristics of secreted aspartic proteases of Candida albicans.

Koelsch G, Tang J, Loy JA, Monod M, Jackson K, Foundling SI, Lin X.

Biochim Biophys Acta. 2000 Jul 14;1480(1-2):117-31.

PMID:
11004559
8.

Secreted aspartic protease 2 of Candida albicans inactivates factor H and the macrophage factor H-receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18).

Svoboda E, Schneider AE, Sándor N, Lermann U, Staib P, Kremlitzka M, Bajtay Z, Barz D, Erdei A, Józsi M.

Immunol Lett. 2015 Nov;168(1):13-21. doi: 10.1016/j.imlet.2015.08.009. Epub 2015 Aug 22.

PMID:
26306739
9.

The yeast Candida albicans evades human complement attack by secretion of aspartic proteases.

Gropp K, Schild L, Schindler S, Hube B, Zipfel PF, Skerka C.

Mol Immunol. 2009 Dec;47(2-3):465-75. doi: 10.1016/j.molimm.2009.08.019. Epub 2009 Oct 31.

PMID:
19880183
10.

The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.

Schaller M, Bein M, Korting HC, Baur S, Hamm G, Monod M, Beinhauer S, Hube B.

Infect Immun. 2003 Jun;71(6):3227-34.

11.

In vitro study of secreted aspartyl proteinases Sap1 to Sap3 and Sap4 to Sap6 expression in Candida albicans pleomorphic forms.

Staniszewska M, Bondaryk M, Siennicka K, Kurek A, Orłowski J, Schaller M, Kurzatkowski W.

Pol J Microbiol. 2012;61(4):247-56.

12.

Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.

Hube B, Sanglard D, Odds FC, Hess D, Monod M, Schäfer W, Brown AJ, Gow NA.

Infect Immun. 1997 Sep;65(9):3529-38.

13.

Serum and saliva antibodies do not inhibit Candida albicans Sap2 proteinase activity using a BSA hydrolysis assay.

Naglik JR, Scott J, Rahman D, Mistry M, Challacombe SJ.

Med Mycol. 2005 Feb;43(1):73-7.

PMID:
15712610
14.

The action of ten secreted aspartic proteases of pathogenic yeast Candida albicans on major human salivary antimicrobial peptide, histatin 5.

Bochenska O, Rapala-Kozik M, Wolak N, Aoki W, Ueda M, Kozik A.

Acta Biochim Pol. 2016;63(3):403-10. doi: 10.18388/abp.2016_1318. Epub 2016 Jul 8.

16.

Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs.

Felk A, Kretschmar M, Albrecht A, Schaller M, Beinhauer S, Nichterlein T, Sanglard D, Korting HC, Schäfer W, Hube B.

Infect Immun. 2002 Jul;70(7):3689-700.

17.

Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis.

Schaller M, Korting HC, Schäfer W, Bastert J, Chen W, Hube B.

Mol Microbiol. 1999 Oct;34(1):169-80.

18.

Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

Correia A, Lermann U, Teixeira L, Cerca F, Botelho S, da Costa RM, Sampaio P, Gärtner F, Morschhäuser J, Vilanova M, Pais C.

Infect Immun. 2010 Nov;78(11):4839-49. doi: 10.1128/IAI.00248-10. Epub 2010 Aug 2.

19.

Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes.

Smolenski G, Sullivan PA, Cutfield SM, Cutfield JF.

Microbiology. 1997 Feb;143 ( Pt 2):349-56.

PMID:
9043112
20.

Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium.

Korting HC, Hube B, Oberbauer S, Januschke E, Hamm G, Albrecht A, Borelli C, Schaller M.

J Med Microbiol. 2003 Aug;52(Pt 8):623-32.

PMID:
12867554

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