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Items: 1 to 20 of 68

1.

ZIC1 overexpression is oncogenic in liposarcoma.

Brill E, Gobble R, Angeles C, Lagos-Quintana M, Crago A, Laxa B, Decarolis P, Zhang L, Antonescu C, Socci ND, Taylor BS, Sander C, Koff A, Singer S.

Cancer Res. 2010 Sep 1;70(17):6891-901. doi: 10.1158/0008-5472.CAN-10-0745. Epub 2010 Aug 16.

2.

Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.

Gobble RM, Qin LX, Brill ER, Angeles CV, Ugras S, O'Connor RB, Moraco NH, Decarolis PL, Antonescu C, Singer S.

Cancer Res. 2011 Apr 1;71(7):2697-705. doi: 10.1158/0008-5472.CAN-10-3588. Epub 2011 Feb 18.

3.

Syndecan-1 regulates adipogenesis: new insights in dedifferentiated liposarcoma tumorigenesis.

Zaragosi LE, Dadone B, Michiels JF, Marty M, Pedeutour F, Dani C, Bianchini L.

Carcinogenesis. 2015 Jan;36(1):32-40. doi: 10.1093/carcin/bgu222. Epub 2014 Oct 24.

PMID:
25344834
4.

Aberrant calreticulin expression is involved in the dedifferentiation of dedifferentiated liposarcoma.

Hisaoka M, Matsuyama A, Nakamoto M.

Am J Pathol. 2012 May;180(5):2076-83. doi: 10.1016/j.ajpath.2012.01.042. Epub 2012 Mar 17.

PMID:
22429966
5.

ZIC1 is silenced and has tumor suppressor function in malignant pleural mesothelioma.

Cheng YY, Kirschner MB, Cheng NC, Gattani S, Klebe S, Edelman JJ, Vallely MP, McCaughan BC, Jin HC, van Zandwijk N, Reid G.

J Thorac Oncol. 2013 Oct;8(10):1317-28. doi: 10.1097/JTO.0b013e3182a0840a.

6.

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

Singer S, Socci ND, Ambrosini G, Sambol E, Decarolis P, Wu Y, O'Connor R, Maki R, Viale A, Sander C, Schwartz GK, Antonescu CR.

Cancer Res. 2007 Jul 15;67(14):6626-36.

7.

Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma.

Ugras S, Brill E, Jacobsen A, Hafner M, Socci ND, Decarolis PL, Khanin R, O'Connor R, Mihailovic A, Taylor BS, Sheridan R, Gimble JM, Viale A, Crago A, Antonescu CR, Sander C, Tuschl T, Singer S.

Cancer Res. 2011 Sep 1;71(17):5659-69. doi: 10.1158/0008-5472.CAN-11-0890. Epub 2011 Jun 21.

8.

MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors.

Gits CM, van Kuijk PF, Jonkers MB, Boersma AW, Smid M, van Ijcken WF, Coindre JM, Chibon F, Verhoef C, Mathijssen RH, den Bakker MA, Verweij J, Sleijfer S, Wiemer EA.

Int J Cancer. 2014 Jul 15;135(2):348-61. doi: 10.1002/ijc.28694. Epub 2014 Jan 16.

9.

The cancer-testis antigen NY-ESO-1 is highly expressed in myxoid and round cell subset of liposarcomas.

Hemminger JA, Ewart Toland A, Scharschmidt TJ, Mayerson JL, Kraybill WG, Guttridge DC, Iwenofu OH.

Mod Pathol. 2013 Feb;26(2):282-8. doi: 10.1038/modpathol.2012.133. Epub 2012 Aug 31.

10.

FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells.

Rodriguez R, Rubio R, Gutierrez-Aranda I, Melen GJ, Elosua C, García-Castro J, Menendez P.

Stem Cells. 2011 Feb;29(2):179-92. doi: 10.1002/stem.571.

11.

Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas.

Taylor BS, DeCarolis PL, Angeles CV, Brenet F, Schultz N, Antonescu CR, Scandura JM, Sander C, Viale AJ, Socci ND, Singer S.

Cancer Discov. 2011 Dec;1(7):587-97. doi: 10.1158/2159-8290.CD-11-0181.

12.

c-Jun amplification and overexpression are oncogenic in liposarcoma but not always sufficient to inhibit the adipocytic differentiation programme.

Snyder EL, Sandstrom DJ, Law K, Fiore C, Sicinska E, Brito J, Bailey D, Fletcher JA, Loda M, Rodig SJ, Dal Cin P, Fletcher CD.

J Pathol. 2009 Jul;218(3):292-300. doi: 10.1002/path.2564.

PMID:
19449367
13.

Chimeric TLS/FUS-CHOP gene expression and the heterogeneity of its junction in human myxoid and round cell liposarcoma.

Kuroda M, Ishida T, Horiuchi H, Kida N, Uozaki H, Takeuchi H, Tsuji K, Imamura T, Mori S, Machinami R, et al.

Am J Pathol. 1995 Nov;147(5):1221-7.

14.

Lipomatous tumors.

Weiss SW.

Monogr Pathol. 1996;38:207-39. Review.

PMID:
8744279
15.

Restoration of C/EBPα in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis.

Wu YV, Okada T, DeCarolis P, Socci N, O'Connor R, Geha RC, Joy Somberg C, Antonescu C, Singer S.

Genes Chromosomes Cancer. 2012 Apr;51(4):313-27. doi: 10.1002/gcc.21917. Epub 2011 Dec 14.

16.

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, Beroukhim R, Major JE, Hatton C, Nicoletti R, Hanna M, Sharpe T, Fennell TJ, Cibulskis K, Onofrio RC, Saito T, Shukla N, Lau C, Nelander S, Silver SJ, Sougnez C, Viale A, Winckler W, Maki RG, Garraway LA, Lash A, Greulich H, Root DE, Sellers WR, Schwartz GK, Antonescu CR, Lander ES, Varmus HE, Ladanyi M, Sander C, Meyerson M, Singer S.

Nat Genet. 2010 Aug;42(8):715-21. doi: 10.1038/ng.619. Epub 2010 Jul 4.

17.

Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma.

Crago AM, Singer S.

Curr Opin Oncol. 2011 Jul;23(4):373-8. doi: 10.1097/CCO.0b013e32834796e6. Review.

18.

Monoclonality of multifocal myxoid liposarcoma: confirmation by analysis of TLS-CHOP or EWS-CHOP rearrangements.

Antonescu CR, Elahi A, Healey JH, Brennan MF, Lui MY, Lewis J, Jhanwar SC, Woodruff JM, Ladanyi M.

Clin Cancer Res. 2000 Jul;6(7):2788-93.

19.
20.

Antiproliferative effects of CDK4/6 inhibition in CDK4-amplified human liposarcoma in vitro and in vivo.

Zhang YX, Sicinska E, Czaplinski JT, Remillard SP, Moss S, Wang Y, Brain C, Loo A, Snyder EL, Demetri GD, Kim S, Kung AL, Wagner AJ.

Mol Cancer Ther. 2014 Sep;13(9):2184-93. doi: 10.1158/1535-7163.MCT-14-0387. Epub 2014 Jul 15.

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