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Items: 1 to 20 of 111

1.

Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice.

Noguchi Y, Nishikata N, Shikata N, Kimura Y, Aleman JO, Young JD, Koyama N, Kelleher JK, Takahashi M, Stephanopoulos G.

PLoS One. 2010 Aug 10;5(8):e12057. doi: 10.1371/journal.pone.0012057.

2.

Dietary lipid-dependent regulation of de novo lipogenesis and lipid partitioning by ketogenic essential amino acids in mice.

Nishikata N, Shikata N, Kimura Y, Noguchi Y.

Nutr Diabetes. 2011 Mar 28;1:e5. doi: 10.1038/nutd.2011.1.

3.

Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules.

Xu L, Kanasaki M, He J, Kitada M, Nagao K, Jinzu H, Noguchi Y, Maegawa H, Kanasaki K, Koya D.

Biochim Biophys Acta. 2013 Oct;1832(10):1605-12. doi: 10.1016/j.bbadis.2013.05.003. Epub 2013 May 11.

4.

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

Diabetes. 2006 Aug;55(8):2159-70.

5.

Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Garbow JR, Doherty JM, Schugar RC, Travers S, Weber ML, Wentz AE, Ezenwajiaku N, Cotter DG, Brunt EM, Crawford PA.

Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G956-67. doi: 10.1152/ajpgi.00539.2010. Epub 2011 Mar 31.

6.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
7.

Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.

Ren LP, Chan SM, Zeng XY, Laybutt DR, Iseli TJ, Sun RQ, Kraegen EW, Cooney GJ, Turner N, Ye JM.

PLoS One. 2012;7(2):e30816. doi: 10.1371/journal.pone.0030816. Epub 2012 Feb 15.

8.

Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism.

Kim MH, Park JS, Jung JW, Byun KW, Kang KS, Lee YS.

Int J Obes (Lond). 2011 Aug;35(8):1019-30. doi: 10.1038/ijo.2010.256. Epub 2010 Dec 14.

PMID:
21157426
9.

Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis.

Monsénégo J, Mansouri A, Akkaoui M, Lenoir V, Esnous C, Fauveau V, Tavernier V, Girard J, Prip-Buus C.

J Hepatol. 2012 Mar;56(3):632-9. doi: 10.1016/j.jhep.2011.10.008. Epub 2011 Oct 25.

PMID:
22037024
10.

Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model.

de Meijer VE, Le HD, Meisel JA, Akhavan Sharif MR, Pan A, Nosé V, Puder M.

Metabolism. 2010 Aug;59(8):1092-105. doi: 10.1016/j.metabol.2009.11.006. Epub 2010 Jan 8.

11.

Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.

Abu-Elheiga L, Wu H, Gu Z, Bressler R, Wakil SJ.

J Biol Chem. 2012 Apr 6;287(15):12578-88. doi: 10.1074/jbc.M111.309559. Epub 2012 Feb 23.

12.

Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury.

Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ.

J Nutr Biochem. 2016 Mar;29:12-20. doi: 10.1016/j.jnutbio.2015.10.020. Epub 2015 Nov 17.

13.

Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice.

Tsuchida T, Shiraishi M, Ohta T, Sakai K, Ishii S.

Metabolism. 2012 Jul;61(7):944-53. doi: 10.1016/j.metabol.2011.10.023. Epub 2011 Dec 7.

PMID:
22154323
14.

Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones.

Geisler CE, Renquist BJ.

J Endocrinol. 2017 Jul;234(1):R1-R21. doi: 10.1530/JOE-16-0513. Epub 2017 Apr 20. Review.

PMID:
28428362
15.

Eicosapentaenoic acid-enriched phospholipid ameliorates insulin resistance and lipid metabolism in diet-induced-obese mice.

Liu X, Xue Y, Liu C, Lou Q, Wang J, Yanagita T, Xue C, Wang Y.

Lipids Health Dis. 2013 Jul 23;12:109. doi: 10.1186/1476-511X-12-109.

16.

Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet.

Ushio M, Nishio Y, Sekine O, Nagai Y, Maeno Y, Ugi S, Yoshizaki T, Morino K, Kume S, Kashiwagi A, Maegawa H.

Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E293-304. doi: 10.1152/ajpendo.00442.2012. Epub 2013 May 28.

17.

A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice.

Sinha-Hikim I, Sinha-Hikim AP, Shen R, Kim HJ, French SW, Vaziri ND, Crum AC, Rajavashisth TB, Norris KC.

Exp Mol Pathol. 2011 Aug;91(1):419-28. doi: 10.1016/j.yexmp.2011.04.009. Epub 2011 May 3. Erratum in: Exp Mol Pathol. 2012 Oct;93(2):282. Vaziri, Nosratola D [corrected to Vaziri, Nosratola D]; Crum, Albert [corrected to Crum, Albert C]. Exp Mol Pathol. 2012 Oct;93(2):281. Kim, H [corrected to Kim, Hyun Ju].

19.

Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation.

Larter CZ, Yeh MM, Cheng J, Williams J, Brown S, dela Pena A, Bell-Anderson KS, Farrell GC.

J Gastroenterol Hepatol. 2008 Feb;23(2):267-75. Epub 2007 Sep 12.

PMID:
17868330
20.

Fructose supplementation worsens the deleterious effects of short-term high-fat feeding on hepatic steatosis and lipid metabolism in adult rats.

Crescenzo R, Bianco F, Coppola P, Mazzoli A, Tussellino M, Carotenuto R, Liverini G, Iossa S.

Exp Physiol. 2014 Sep;99(9):1203-13. doi: 10.1113/expphysiol.2014.079632. Epub 2014 Jun 27.

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