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Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism.

Marchant D, Singhera GK, Utokaparch S, Hackett TL, Boyd JH, Luo Z, Si X, Dorscheid DR, McManus BM, Hegele RG.

J Virol. 2010 Nov;84(21):11359-73. doi: 10.1128/JVI.00804-10. Epub 2010 Aug 11.


Inhibition of respiratory syncytial virus replication and virus-induced p38 kinase activity by berberine.

Shin HB, Choi MS, Yi CM, Lee J, Kim NJ, Inn KS.

Int Immunopharmacol. 2015 Jul;27(1):65-8. doi: 10.1016/j.intimp.2015.04.045. Epub 2015 May 2.


Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B.

Xu F, Xu Z, Zhang R, Wu Z, Lim JH, Koga T, Li JD, Shen H.

Respir Res. 2008 Jan 31;9:16. doi: 10.1186/1465-9921-9-16.


MAPK activation is involved in posttranscriptional regulation of RSV-induced RANTES gene expression.

Pazdrak K, Olszewska-Pazdrak B, Liu T, Takizawa R, Brasier AR, Garofalo RP, Casola A.

Am J Physiol Lung Cell Mol Physiol. 2002 Aug;283(2):L364-72.


A novel p38 mitogen activated protein kinase (MAPK) specific inhibitor suppresses respiratory syncytial virus and influenza A virus replication by inhibiting virus-induced p38 MAPK activation.

Choi MS, Heo J, Yi CM, Ban J, Lee NJ, Lee NR, Kim SW, Kim NJ, Inn KS.

Biochem Biophys Res Commun. 2016 Aug 26;477(3):311-6. doi: 10.1016/j.bbrc.2016.06.111. Epub 2016 Jun 23.


Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1.

Qadri I, Iwahashi M, Capasso JM, Hopken MW, Flores S, Schaack J, Simon FR.

Biochem J. 2004 Mar 15;378(Pt 3):919-28. Erratum in: Biochem J. 2004 Jul 1;381(Pt 3):951.


Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways.

Gorina R, Font-Nieves M, Márquez-Kisinousky L, Santalucia T, Planas AM.

Glia. 2011 Feb;59(2):242-55. doi: 10.1002/glia.21094.


Nerve growth factor-induced stimulation of p38 mitogen-activated protein kinase in PC12 cells is partially mediated via G(i/o) proteins.

Yung LY, Tso PH, Wu EH, Yu JC, Ip NY, Wong YH.

Cell Signal. 2008 Aug;20(8):1538-44. doi: 10.1016/j.cellsig.2008.04.007. Epub 2008 Apr 18.


Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

Lavoie JN, L'Allemain G, Brunet A, Müller R, Pouysségur J.

J Biol Chem. 1996 Aug 23;271(34):20608-16.


Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway.

Balloy V, Sallenave JM, Wu Y, Touqui L, Latgé JP, Si-Tahar M, Chignard M.

J Biol Chem. 2008 Nov 7;283(45):30513-21. doi: 10.1074/jbc.M803149200. Epub 2008 Aug 14.


JNK and p38 mitogen-activated protein kinase pathways contribute to porcine circovirus type 2 infection.

Wei L, Zhu Z, Wang J, Liu J.

J Virol. 2009 Jun;83(12):6039-47. doi: 10.1128/JVI.00135-09. Epub 2009 Apr 1.


The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage.

Thobe BM, Frink M, Hildebrand F, Schwacha MG, Hubbard WJ, Choudhry MA, Chaudry IH.

J Cell Physiol. 2007 Mar;210(3):667-75. Erratum in: J Cell Physiol. 2010 Nov;225(3):915.


Cell-specific activation profile of extracellular signal-regulated kinase 1/2, Jun N-terminal kinase, and p38 mitogen-activated protein kinases in asthmatic airways.

Liu W, Liang Q, Balzar S, Wenzel S, Gorska M, Alam R.

J Allergy Clin Immunol. 2008 Apr;121(4):893-902.e2. doi: 10.1016/j.jaci.2008.02.004.


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