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Effect of Borrelia burgdorferi OspC at the site of inoculation in mouse skin.

Antonara S, Ristow L, McCarthy J, Coburn J.

Infect Immun. 2010 Nov;78(11):4723-33. doi: 10.1128/IAI.00464-10. Epub 2010 Aug 9.


Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.

Carrasco SE, Troxell B, Yang Y, Brandt SL, Li H, Sandusky GE, Condon KW, Serezani CH, Yang XF.

Infect Immun. 2015 Dec;83(12):4848-60. doi: 10.1128/IAI.01215-15. Epub 2015 Oct 5.


Identification of an ospC operator critical for immune evasion of Borrelia burgdorferi.

Xu Q, McShan K, Liang FT.

Mol Microbiol. 2007 Apr;64(1):220-31.


Artificial regulation of ospC expression in Borrelia burgdorferi.

Gilbert MA, Morton EA, Bundle SF, Samuels DS.

Mol Microbiol. 2007 Feb;63(4):1259-73.


Lipoprotein succession in Borrelia burgdorferi: similar but distinct roles for OspC and VlsE at different stages of mammalian infection.

Tilly K, Bestor A, Rosa PA.

Mol Microbiol. 2013 Jul;89(2):216-27. doi: 10.1111/mmi.12271. Epub 2013 Jun 7.


Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection.

Tilly K, Krum JG, Bestor A, Jewett MW, Grimm D, Bueschel D, Byram R, Dorward D, Vanraden MJ, Stewart P, Rosa P.

Infect Immun. 2006 Jun;74(6):3554-64.


Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences.

Xu Q, McShan K, Liang FT.

Mol Microbiol. 2008 Jul;69(1):15-29. doi: 10.1111/j.1365-2958.2008.06264.x. Epub 2008 Apr 28.


Identification of Borrelia burgdorferi ospC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design.

Rhodes DV, Earnhart CG, Mather TN, Meeus PF, Marconi RT.

Vet J. 2013 Nov;198(2):412-8. doi: 10.1016/j.tvjl.2013.07.019. Epub 2013 Aug 17.


OspC-independent infection and dissemination by host-adapted Borrelia burgdorferi.

Tilly K, Bestor A, Dulebohn DP, Rosa PA.

Infect Immun. 2009 Jul;77(7):2672-82. doi: 10.1128/IAI.01193-08. Epub 2009 Apr 27.


OspC is potent plasminogen receptor on surface of Borrelia burgdorferi.

Önder Ö, Humphrey PT, McOmber B, Korobova F, Francella N, Greenbaum DC, Brisson D.

J Biol Chem. 2012 May 11;287(20):16860-8. doi: 10.1074/jbc.M111.290775. Epub 2012 Mar 20.


Invasive potential of Borrelia burgdorferi sensu stricto ospC type L strains increases the possible disease risk to humans in the regions of their distribution.

Golovchenko M, Sima R, Hajdusek O, Grubhoffer L, Oliver JH Jr, Rudenko N.

Parasit Vectors. 2014 Nov 28;7:538. doi: 10.1186/s13071-014-0538-y.


Modification of Borrelia burgdorferi to overproduce OspA or VlsE alters its infectious behaviour.

Xu Q, McShan K, Liang FT.

Microbiology. 2008 Nov;154(Pt 11):3420-9. doi: 10.1099/mic.0.2008/019737-0.


Essential role of the response regulator Rrp2 in the infectious cycle of Borrelia burgdorferi.

Boardman BK, He M, Ouyang Z, Xu H, Pang X, Yang XF.

Infect Immun. 2008 Sep;76(9):3844-53. doi: 10.1128/IAI.00467-08. Epub 2008 Jun 23.


Rapid clearance of Lyme disease spirochetes lacking OspC from skin.

Tilly K, Bestor A, Jewett MW, Rosa P.

Infect Immun. 2007 Mar;75(3):1517-9. Epub 2006 Dec 11.


Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice.

Bernard Q, Wang Z, Di Nardo A, Boulanger N.

Parasit Vectors. 2017 Jun 27;10(1):313. doi: 10.1186/s13071-017-2243-0.


Delineating the requirement for the Borrelia burgdorferi virulence factor OspC in the mammalian host.

Stewart PE, Wang X, Bueschel DM, Clifton DR, Grimm D, Tilly K, Carroll JA, Weis JJ, Rosa PA.

Infect Immun. 2006 Jun;74(6):3547-53.


Outer surface protein C is a dissemination-facilitating factor of Borrelia burgdorferi during mammalian infection.

Seemanapalli SV, Xu Q, McShan K, Liang FT.

PLoS One. 2010 Dec 31;5(12):e15830. doi: 10.1371/journal.pone.0015830.


Verification and dissection of the ospC operator by using flaB promoter as a reporter in Borrelia burgdorferi.

Xu Q, McShan K, Liang FT.

Microb Pathog. 2008 Jul;45(1):70-8. doi: 10.1016/j.micpath.2008.03.002. Epub 2008 Mar 25.


Temporal analysis of Borrelia burgdorferi Erp protein expression throughout the mammal-tick infectious cycle.

Miller JC, von Lackum K, Babb K, McAlister JD, Stevenson B.

Infect Immun. 2003 Dec;71(12):6943-52.

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