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Items: 1 to 20 of 49

1.

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654.

Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Kehlbach R, Rodemann HP.

FEBS Lett. 2010 Sep 24;584(18):3878-84. doi: 10.1016/j.febslet.2010.08.005. Epub 2010 Aug 7.

2.

Characterization of a novel tripartite nuclear localization sequence in the EGFR family.

Hsu SC, Hung MC.

J Biol Chem. 2007 Apr 6;282(14):10432-40. Epub 2007 Feb 5.

3.

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.

Dittmann K, Mayer C, Kehlbach R, Rodemann HP.

Mol Cancer. 2008 Sep 12;7:69. doi: 10.1186/1476-4598-7-69.

4.

The radioprotector Bowman-Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport.

Dittmann K, Mayer C, Kehlbach R, Rodemann HP.

Radiother Oncol. 2008 Mar;86(3):375-82. doi: 10.1016/j.radonc.2008.01.007. Epub 2008 Jan 30.

PMID:
18237807
5.

Radiation-induced lipid peroxidation activates src kinase and triggers nuclear EGFR transport.

Dittmann K, Mayer C, Kehlbach R, Rothmund MC, Peter Rodemann H.

Radiother Oncol. 2009 Sep;92(3):379-82. doi: 10.1016/j.radonc.2009.06.003. Epub 2009 Jun 25.

PMID:
19560222
6.

Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation.

Wanner G, Mayer C, Kehlbach R, Rodemann HP, Dittmann K.

Radiother Oncol. 2008 Mar;86(3):383-90. Epub 2007 Nov 26.

PMID:
18037521
7.

Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access.

Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Kehlbach R, Rodemann HP.

Radiother Oncol. 2011 Jun;99(3):317-22. doi: 10.1016/j.radonc.2011.06.001. Epub 2011 Jun 23.

PMID:
21704408
8.

Phosphorylation of Thr654 but not Thr669 within the juxtamembrane domain of the EGF receptor inhibits calmodulin binding.

Aifa S, Frikha F, Miled N, Johansen K, Lundström I, Svensson SP.

Biochem Biophys Res Commun. 2006 Aug 25;347(2):381-7. Epub 2006 Jun 9.

PMID:
16793002
9.

Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase.

Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Raju U, Milas L, Chen DJ, Kehlbach R, Rodemann HP.

J Biol Chem. 2005 Sep 2;280(35):31182-9. Epub 2005 Jul 5.

10.

Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism.

Dittmann KH, Mayer C, Ohneseit PA, Raju U, Andratschke NH, Milas L, Rodemann HP.

Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):203-12. Epub 2007 Nov 8.

PMID:
17996386
11.

The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation.

Dittmann K, Mayer C, Wanner G, Kehlbach R, Rodemann HP.

Radiother Oncol. 2007 Sep;84(3):328-34. Epub 2007 Aug 21.

PMID:
17714814
12.

Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2.

Sturla LM, Amorino G, Alexander MS, Mikkelsen RB, Valerie K, Schmidt-Ullrichr RK.

J Biol Chem. 2005 Apr 15;280(15):14597-604. Epub 2005 Feb 11.

13.

Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1.

Lo HW, Ali-Seyed M, Wu Y, Bartholomeusz G, Hsu SC, Hung MC.

J Cell Biochem. 2006 Aug 15;98(6):1570-83.

PMID:
16552725
14.

Epidermal growth factor promotes epidermal growth factor receptor nuclear accumulation by a pathway dependent on cytoskeleton integrity in human breast cancer cells.

Cortes-Reynosa P, Robledo T, Salazar EP.

Arch Med Res. 2009 Jul;40(5):331-8. doi: 10.1016/j.arcmed.2009.06.007.

PMID:
19766894
15.

Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity.

Dittmann K, Mayer C, Rodemann HP.

Radiother Oncol. 2005 Aug;76(2):157-61.

PMID:
16024112
16.

Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity.

Lammering G, Hewit TH, Holmes M, Valerie K, Hawkins W, Lin PS, Mikkelsen RB, Schmidt-Ullrich RK.

Clin Cancer Res. 2004 Oct 1;10(19):6732-43.

17.

The juxtamembrane region of the epidermal growth factor receptor is required for phosphorylation of Galpha(s).

Poppleton HM, Sun H, Mullenix JB, Wiepz GJ, Bertics PJ, Patel TB.

Arch Biochem Biophys. 2000 Nov 15;383(2):309-17.

PMID:
11185568
18.

Activation of epidermal growth factor receptor and its downstream signaling pathway by nitric oxide in response to ionizing radiation.

Lee HC, An S, Lee H, Woo SH, Jin HO, Seo SK, Choe TB, Yoo DH, Lee SJ, Hong YJ, Park MJ, Rhee CH, Park IC, Hong SI.

Mol Cancer Res. 2008 Jun;6(6):996-1002. doi: 10.1158/1541-7786.MCR-08-0113.

19.

Nucleocytoplasmic shuttling of BID is involved in regulating its activities in the DNA-damage response.

Oberkovitz G, Regev L, Gross A.

Cell Death Differ. 2007 Sep;14(9):1628-34. Epub 2007 Jun 22.

20.

Modulation of the protein tyrosine kinase activity and autophosphorylation of the epidermal growth factor receptor by its juxtamembrane region.

Poppleton HM, Wiepz GJ, Bertics PJ, Patel TB.

Arch Biochem Biophys. 1999 Mar 15;363(2):227-36.

PMID:
10068444

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