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Items: 1 to 20 of 106

1.

Role of antibodies in developing drugs that target G-protein-coupled receptor dimers.

Hipser C, Bushlin I, Gupta A, Gomes I, Devi LA.

Mt Sinai J Med. 2010 Jul-Aug;77(4):374-80. doi: 10.1002/msj.20199. Review.

2.

Physiological relevance of GPCR oligomerization and its impact on drug discovery.

Panetta R, Greenwood MT.

Drug Discov Today. 2008 Dec;13(23-24):1059-66. doi: 10.1016/j.drudis.2008.09.002. Epub 2008 Oct 14. Review.

PMID:
18824244
3.

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

Casadó V, Cortés A, Mallol J, Pérez-Capote K, Ferré S, Lluis C, Franco R, Canela EI.

Pharmacol Ther. 2009 Nov;124(2):248-57. doi: 10.1016/j.pharmthera.2009.07.005. Epub 2009 Aug 5. Review.

PMID:
19664655
4.

Antibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and function.

Gomes I, Gupta A, Bushlin I, Devi LA.

Front Pharmacol. 2014 Dec 3;5:268. doi: 10.3389/fphar.2014.00268. eCollection 2014. Review.

5.

Bivalent ligands as specific pharmacological tools for G protein-coupled receptor dimers.

Berque-Bestel I, Lezoualc'h F, Jockers R.

Curr Drug Discov Technol. 2008 Dec;5(4):312-8. Review.

PMID:
19075611
6.

G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives.

Ferré S, Casadó V, Devi LA, Filizola M, Jockers R, Lohse MJ, Milligan G, Pin JP, Guitart X.

Pharmacol Rev. 2014 Feb 10;66(2):413-34. doi: 10.1124/pr.113.008052. Print 2014. Review.

7.

Dimerization in GPCR mobility and signaling.

Lohse MJ.

Curr Opin Pharmacol. 2010 Feb;10(1):53-8. doi: 10.1016/j.coph.2009.10.007. Epub 2009 Nov 10. Review.

PMID:
19910252
8.

The future of G protein-coupled receptors as targets in drug discovery.

Lundstrom K.

IDrugs. 2005 Nov;8(11):909-13.

PMID:
16254784
9.

Heterodimerization of g protein-coupled receptors: specificity and functional significance.

Prinster SC, Hague C, Hall RA.

Pharmacol Rev. 2005 Sep;57(3):289-98. Review.

10.

Prime time for G-protein-coupled receptor heteromers as therapeutic targets for CNS disorders: the dopamine D₁-D₃ receptor heteromer.

Ferré S, Lluis C, Lanciego JL, Franco R.

CNS Neurol Disord Drug Targets. 2010 Nov;9(5):596-600. Review.

PMID:
20632968
11.

G-protein-coupled heteromers: regulation in disease.

Gomes I, Gupta A, Devi LA.

Methods Enzymol. 2013;521:219-38. doi: 10.1016/B978-0-12-391862-8.00012-0.

12.

G-protein-coupled receptor heteromers: function and ligand pharmacology.

Franco R, Casadó V, Cortés A, Mallol J, Ciruela F, Ferré S, Lluis C, Canela EI.

Br J Pharmacol. 2008 Mar;153 Suppl 1:S90-8. Epub 2007 Nov 26. Review.

13.

Simultaneous method for analyzing dimerization and signaling of G-protein-coupled receptor in yeast by dual-color reporter system.

Nakamura Y, Takemoto N, Ishii J, Kondo A.

Biotechnol Bioeng. 2014 Mar;111(3):586-96.

PMID:
24122388
14.

Understanding the role of heteroreceptor complexes in the central nervous system.

Fuxe K, Borroto-Escuela D, Fisone G, Agnati LF, Tanganelli S.

Curr Protein Pept Sci. 2014;15(7):647.

PMID:
25256022
15.
16.

Opioid-receptor-heteromer-specific trafficking and pharmacology.

van Rijn RM, Whistler JL, Waldhoer M.

Curr Opin Pharmacol. 2010 Feb;10(1):73-9. doi: 10.1016/j.coph.2009.09.007. Epub 2009 Oct 19. Review.

17.

Receptor heteromerization and drug discovery.

Rozenfeld R, Devi LA.

Trends Pharmacol Sci. 2010 Mar;31(3):124-30. doi: 10.1016/j.tips.2009.11.008. Epub 2010 Jan 7.

18.

G protein-coupled receptor dimerization: function and ligand pharmacology.

Milligan G.

Mol Pharmacol. 2004 Jul;66(1):1-7. Review.

19.

Exploring a role for heteromerization in GPCR signalling specificity.

Rozenfeld R, Devi LA.

Biochem J. 2011 Jan 1;433(1):11-8. doi: 10.1042/BJ20100458. Review.

20.

G protein-coupled receptor heteromer identification technology: identification and profiling of GPCR heteromers.

Mustafa S, Pfleger KD.

J Lab Autom. 2011 Aug;16(4):285-91. doi: 10.1016/j.jala.2011.03.002. Epub 2011 May 31.

PMID:
21764024

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