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Items: 1 to 20 of 302

1.

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling.

Fros JJ, Liu WJ, Prow NA, Geertsema C, Ligtenberg M, Vanlandingham DL, Schnettler E, Vlak JM, Suhrbier A, Khromykh AA, Pijlman GP.

J Virol. 2010 Oct;84(20):10877-87. doi: 10.1128/JVI.00949-10.

2.

The C-terminal domain of chikungunya virus nsP2 independently governs viral RNA replication, cytopathicity, and inhibition of interferon signaling.

Fros JJ, van der Maten E, Vlak JM, Pijlman GP.

J Virol. 2013 Sep;87(18):10394-400. doi: 10.1128/JVI.00884-13.

3.

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A.

J Virol. 2015 Mar;89(6):3145-62. doi: 10.1128/JVI.03213-14. Erratum in: J Virol. 2016 Sep 1;90(17):8030.

4.

Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression.

Kaur P, Thiruchelvan M, Lee RC, Chen H, Chen KC, Ng ML, Chu JJ.

Antimicrob Agents Chemother. 2013 Jan;57(1):155-67. doi: 10.1128/AAC.01467-12.

5.

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

Pohjala L, Utt A, Varjak M, Lulla A, Merits A, Ahola T, Tammela P.

PLoS One. 2011;6(12):e28923. doi: 10.1371/journal.pone.0028923.

6.

Heat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infection.

Das I, Basantray I, Mamidi P, Nayak TK, B M P, Chattopadhyay S, Chattopadhyay S.

PLoS One. 2014 Jun 24;9(6):e100531. doi: 10.1371/journal.pone.0100531. Erratum in: PLoS One. 2015;10(3):e0122906.

7.

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease.

Couderc T, Chrétien F, Schilte C, Disson O, Brigitte M, Guivel-Benhassine F, Touret Y, Barau G, Cayet N, Schuffenecker I, Desprès P, Arenzana-Seisdedos F, Michault A, Albert ML, Lecuit M.

PLoS Pathog. 2008 Feb 8;4(2):e29. doi: 10.1371/journal.ppat.0040029.

8.

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication.

Scholte FE, Tas A, Albulescu IC, Žusinaite E, Merits A, Snijder EJ, van Hemert MJ.

J Virol. 2015 Apr;89(8):4457-69. doi: 10.1128/JVI.03612-14.

9.

Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection.

Thon-Hon VG, Denizot M, Li-Pat-Yuen G, Giry C, Jaffar-Bandjee MC, Gasque P.

Virol J. 2012 Sep 20;9:213. doi: 10.1186/1743-422X-9-213.

10.

Chikungunya virus isolates with/without A226V mutation show different sensitivity to IFN-a, but similar replication kinetics in non human primate cells.

Bordi L, Meschi S, Selleri M, Lalle E, Castilletti C, Carletti F, Chiappini R, Di Caro A, Capobianchi MR.

New Microbiol. 2011 Jan;34(1):87-91.

PMID:
21344151
11.

Proteomic profiling of chikungunya virus-infected human muscle cells: reveal the role of cytoskeleton network in CHIKV replication.

Issac TH, Tan EL, Chu JJ.

J Proteomics. 2014 Aug 28;108:445-64. doi: 10.1016/j.jprot.2014.06.003.

PMID:
24933005
12.

Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEAS-2B cells.

Li YG, Siripanyaphinyo U, Tumkosit U, Noranate N, A-Nuegoonpipat A, Pan Y, Kameoka M, Kurosu T, Ikuta K, Takeda N, Anantapreecha S.

Virol J. 2012 Jun 14;9:114. doi: 10.1186/1743-422X-9-114.

13.

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component.

Bouraï M, Lucas-Hourani M, Gad HH, Drosten C, Jacob Y, Tafforeau L, Cassonnet P, Jones LM, Judith D, Couderc T, Lecuit M, André P, Kümmerer BM, Lotteau V, Desprès P, Tangy F, Vidalain PO.

J Virol. 2012 Mar;86(6):3121-34. doi: 10.1128/JVI.06390-11.

14.

A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2.

Lucas-Hourani M, Lupan A, Desprès P, Thoret S, Pamlard O, Dubois J, Guillou C, Tangy F, Vidalain PO, Munier-Lehmann H.

J Biomol Screen. 2013 Feb;18(2):172-9. doi: 10.1177/1087057112460091.

PMID:
22983165
15.

The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling.

Laurent-Rolle M, Boer EF, Lubick KJ, Wolfinbarger JB, Carmody AB, Rockx B, Liu W, Ashour J, Shupert WL, Holbrook MR, Barrett AD, Mason PW, Bloom ME, García-Sastre A, Khromykh AA, Best SM.

J Virol. 2010 Apr;84(7):3503-15. doi: 10.1128/JVI.01161-09.

16.

A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization.

Silva LA, Khomandiak S, Ashbrook AW, Weller R, Heise MT, Morrison TE, Dermody TS.

J Virol. 2014 Mar;88(5):2385-97. doi: 10.1128/JVI.03116-13.

17.

Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.

White LK, Sali T, Alvarado D, Gatti E, Pierre P, Streblow D, Defilippis VR.

J Virol. 2011 Jan;85(1):606-20. doi: 10.1128/JVI.00767-10.

20.

Expression of plasmid-based shRNA against the E1 and nsP1 genes effectively silenced Chikungunya virus replication.

Lam S, Chen KC, Ng MM, Chu JJ.

PLoS One. 2012;7(10):e46396. doi: 10.1371/journal.pone.0046396.

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