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Items: 1 to 20 of 73


Impaired pancreatic development in Hif2-alpha deficient mice.

Chen H, Houshmand G, Mishra S, Fong GH, Gittes GK, Esni F.

Biochem Biophys Res Commun. 2010 Aug 27;399(3):440-5. doi: 10.1016/j.bbrc.2010.07.111. Epub 2010 Aug 3.


Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment.

Qu X, Afelik S, Jensen JN, Bukys MA, Kobberup S, Schmerr M, Xiao F, Nyeng P, Veronica Albertoni M, Grapin-Botton A, Jensen J.

Dev Biol. 2013 Apr 1;376(1):1-12. doi: 10.1016/j.ydbio.2013.01.021. Epub 2013 Jan 29.


Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.

Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF, Fujimoto K, Doi R, Kageyama R, Wright CV, Chiba T.

J Clin Invest. 2006 Jun;116(6):1484-93. Epub 2006 May 18.


Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia.

Pawlus MR, Wang L, Ware K, Hu CJ.

Mol Cell Biol. 2012 Nov;32(22):4595-610. doi: 10.1128/MCB.00724-12. Epub 2012 Sep 10.


Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine.

Li HJ, Kapoor A, Giel-Moloney M, Rindi G, Leiter AB.

Dev Biol. 2012 Nov 15;371(2):156-69. doi: 10.1016/j.ydbio.2012.08.023. Epub 2012 Sep 1.


The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.

Kim SY, Rane SG.

Development. 2011 May;138(10):1903-12. doi: 10.1242/dev.061481. Epub 2011 Apr 13.


Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo.

Lin TY, Chou CF, Chung HY, Chiang CY, Li CH, Wu JL, Lin HJ, Pai TW, Hu CH, Tzou WS.

PLoS One. 2014 Jul 7;9(7):e101980. doi: 10.1371/journal.pone.0101980. eCollection 2014.


A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.

Shih HP, Kopp JL, Sandhu M, Dubois CL, Seymour PA, Grapin-Botton A, Sander M.

Development. 2012 Jul;139(14):2488-99. doi: 10.1242/dev.078634. Epub 2012 Jun 6.


Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development.

Huang W, Wang G, Delaspre F, Vitery Mdel C, Beer RL, Parsons MJ.

Dev Biol. 2014 Oct 1;394(1):83-93. doi: 10.1016/j.ydbio.2014.07.021. Epub 2014 Aug 13.


The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3.

Xu Y, Wang S, Zhang J, Zhao A, Stanger BZ, Gu G.

Dev Biol. 2006 Sep 15;297(2):340-9. Epub 2006 Apr 27.


Notch signaling controls multiple steps of pancreatic differentiation.

Murtaugh LC, Stanger BZ, Kwan KM, Melton DA.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14920-5. Epub 2003 Dec 1.


Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas.

Golson ML, Le Lay J, Gao N, Brämswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH.

Mech Dev. 2009 Aug-Sep;126(8-9):687-99. doi: 10.1016/j.mod.2009.05.005. Epub 2009 Jun 6.


Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.

Bankaitis ED, Bechard ME, Wright CV.

Genes Dev. 2015 Oct 15;29(20):2203-16. doi: 10.1101/gad.267914.115.


Expression of the Notch signaling pathway and effect on exocrine cell proliferation in adult rat pancreas.

Rooman I, De Medts N, Baeyens L, Lardon J, De Breuck S, Heimberg H, Bouwens L.

Am J Pathol. 2006 Oct;169(4):1206-14.


Hypoxia requires notch signaling to maintain the undifferentiated cell state.

Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J, Ruas JL, Poellinger L, Lendahl U, Bondesson M.

Dev Cell. 2005 Nov;9(5):617-28.


Notch signalling controls pancreatic cell differentiation.

Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H.

Nature. 1999 Aug 26;400(6747):877-81.


Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway.

Lee JH, Suk J, Park J, Kim SB, Kwak SS, Kim JW, Lee CH, Byun B, Ahn JK, Joe CO.

Mol Cancer Res. 2009 Oct;7(10):1663-71. doi: 10.1158/1541-7786.MCR-09-0191. Epub 2009 Oct 6.


Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas.

Esni F, Ghosh B, Biankin AV, Lin JW, Albert MA, Yu X, MacDonald RJ, Civin CI, Real FX, Pack MA, Ball DW, Leach SD.

Development. 2004 Sep;131(17):4213-24. Epub 2004 Jul 27.


Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A.

Nat Genet. 2004 Jan;36(1):83-7. Epub 2003 Dec 14.


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