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Items: 1 to 20 of 89

1.

Hemozoin-free Plasmodium falciparum mitochondria for physiological and drug susceptibility studies.

Mather MW, Morrisey JM, Vaidya AB.

Mol Biochem Parasitol. 2010 Dec;174(2):150-3. doi: 10.1016/j.molbiopara.2010.07.006. Epub 2010 Jul 30.

2.

Novel inhibitors of the Plasmodium falciparum electron transport chain.

Stocks PA, Barton V, Antoine T, Biagini GA, Ward SA, O'Neill PM.

Parasitology. 2014 Jan;141(1):50-65. doi: 10.1017/S0031182013001571. Review.

PMID:
24401337
3.

Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum.

Dickerman BK, Elsworth B, Cobbold SA, Nie CQ, McConville MJ, Crabb BS, Gilson PR.

Sci Rep. 2016 Nov 22;6:37502. doi: 10.1038/srep37502.

5.
6.

Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function.

Ke H, Morrisey JM, Ganesan SM, Painter HJ, Mather MW, Vaidya AB.

Eukaryot Cell. 2011 Aug;10(8):1053-61. doi: 10.1128/EC.05049-11. Epub 2011 Jun 17.

7.

The effects of antimalarials on the Plasmodium falciparum dihydroorotate dehydrogenase.

Ittarat I, Asawamahasakda W, Meshnick SR.

Exp Parasitol. 1994 Aug;79(1):50-6.

8.

Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex.

Biagini GA, Fisher N, Berry N, Stocks PA, Meunier B, Williams DP, Bonar-Law R, Bray PG, Owen A, O'Neill PM, Ward SA.

Mol Pharmacol. 2008 May;73(5):1347-55. doi: 10.1124/mol.108.045120. Epub 2008 Mar 4.

9.

Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.

Nixon GL, Pidathala C, Shone AE, Antoine T, Fisher N, O'Neill PM, Ward SA, Biagini GA.

Future Med Chem. 2013 Sep;5(13):1573-91. doi: 10.4155/fmc.13.121. Erratum in: Future Med Chem. 2013 Oct;5(16):2010.

10.

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.

Biagini GA, Fisher N, Shone AE, Mubaraki MA, Srivastava A, Hill A, Antoine T, Warman AJ, Davies J, Pidathala C, Amewu RK, Leung SC, Sharma R, Gibbons P, Hong DW, Pacorel B, Lawrenson AS, Charoensutthivarakul S, Taylor L, Berger O, Mbekeani A, Stocks PA, Nixon GL, Chadwick J, Hemingway J, Delves MJ, Sinden RE, Zeeman AM, Kocken CH, Berry NG, O'Neill PM, Ward SA.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8298-303. doi: 10.1073/pnas.1205651109. Epub 2012 May 7.

11.

Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum.

Painter HJ, Morrisey JM, Mather MW, Vaidya AB.

Nature. 2007 Mar 1;446(7131):88-91.

PMID:
17330044
12.

Transcript level responses of Plasmodium falciparum to antimycin A.

Tarr SJ, Nisbet RE, Howe CJ.

Protist. 2012 Sep;163(5):755-66. doi: 10.1016/j.protis.2012.01.003. Epub 2012 Apr 12.

13.

Mitochondrial RNA polymerase is an essential enzyme in erythrocytic stages of Plasmodium falciparum.

Ke H, Morrisey JM, Ganesan SM, Mather MW, Vaidya AB.

Mol Biochem Parasitol. 2012 Sep;185(1):48-51. doi: 10.1016/j.molbiopara.2012.05.001. Epub 2012 May 26.

14.

Mitochondrial electron transport inhibition and viability of intraerythrocytic Plasmodium falciparum.

Painter HJ, Morrisey JM, Vaidya AB.

Antimicrob Agents Chemother. 2010 Dec;54(12):5281-7. doi: 10.1128/AAC.00937-10. Epub 2010 Sep 20.

15.

Atovaquone tolerance in Plasmodium falciparum parasites selected for high-level resistance to a dihydroorotate dehydrogenase inhibitor.

Guler JL, White J 3rd, Phillips MA, Rathod PK.

Antimicrob Agents Chemother. 2015 Jan;59(1):686-9. doi: 10.1128/AAC.02347-14. Epub 2014 Oct 20.

16.

Direct evidence for the atovaquone action on the Plasmodium cytochrome bc1 complex.

Siregar JE, Kurisu G, Kobayashi T, Matsuzaki M, Sakamoto K, Mi-ichi F, Watanabe Y, Hirai M, Matsuoka H, Syafruddin D, Marzuki S, Kita K.

Parasitol Int. 2015 Jun;64(3):295-300. doi: 10.1016/j.parint.2014.09.011. Epub 2014 Sep 28.

17.
18.

Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection.

Ganesan SM, Morrisey JM, Ke H, Painter HJ, Laroiya K, Phillips MA, Rathod PK, Mather MW, Vaidya AB.

Mol Biochem Parasitol. 2011 May;177(1):29-34. doi: 10.1016/j.molbiopara.2011.01.004. Epub 2011 Jan 18.

19.

In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth.

Ross LS, Gamo FJ, Lafuente-Monasterio MJ, Singh OM, Rowland P, Wiegand RC, Wirth DF.

J Biol Chem. 2014 Jun 27;289(26):17980-95. doi: 10.1074/jbc.M114.558353. Epub 2014 Apr 29.

20.

Mitochondria of mammalian Plasmodium spp.

Fry M, Beesley JE.

Parasitology. 1991 Feb;102 Pt 1:17-26.

PMID:
2038500

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