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Items: 1 to 20 of 115

1.

GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.

Lu X, Roberts E, Xia F, Sanchez-Alavez M, Liu T, Baldwin R, Wu S, Chang J, Wasterlain CG, Bartfai T.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15229-34. doi: 10.1073/pnas.1008986107.

2.

Regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors.

Mazarati A, Lu X.

Neuropeptides. 2005 Jun;39(3):277-80. Review.

PMID:
15944022
3.

Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity.

Lu X, Mazarati A, Sanna P, Shinmei S, Bartfai T.

Neuropeptides. 2005 Jun;39(3):147-52.

PMID:
15944003
4.
5.

Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.

Robertson CR, Scholl EA, Pruess TH, Green BR, White HS, Bulaj G.

J Med Chem. 2010 Feb 25;53(4):1871-5. doi: 10.1021/jm9018349.

6.

Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex.

Borroto-Escuela DO, Narvaez M, Di Palma M, Calvo F, Rodriguez D, Millon C, Carlsson J, Agnati LF, Garriga P, Díaz-Cabiale Z, Fuxe K.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):347-53. doi: 10.1016/j.bbrc.2014.08.061.

PMID:
25152404
7.
8.

The role of galanin receptors in anticonvulsant effects of low-frequency stimulation in perforant path-kindled rats.

Sadegh M, Mirnajafi-Zadeh J, Javan M, Fathollahi Y, Mohammad-Zadeh M, Jahanshahi A, Noorbakhsh SM.

Neuroscience. 2007 Dec 5;150(2):396-403.

PMID:
17993248
10.

Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus.

Mazarati A, Lu X, Kilk K, Langel U, Wasterlain C, Bartfai T.

Eur J Neurosci. 2004 Jun;19(12):3235-44.

PMID:
15217380
11.

Constitutive and ligand-induced internalization of EGFP-tagged galanin R2 and Rl receptors in PC12 cells.

Xia S, Kjaer S, Zheng K, Hu PS, Xu T, Hökfelt T, Xu ZQ.

Neuropeptides. 2005 Jun;39(3):173-8.

PMID:
15885774
12.

Identification and characterization of the chicken galanin receptor GalR2 and a novel GalR2-like receptor (GalR2-L).

Ho JC, Jacobs T, Wang Y, Leung FC.

Gen Comp Endocrinol. 2012 Nov 1;179(2):305-12. doi: 10.1016/j.ygcen.2012.09.005.

PMID:
22982974
13.

Analysis of the contribution of galanin receptors 1 and 2 to the central actions of galanin-like peptide.

Krasnow SM, Hohmann JG, Gragerov A, Clifton DK, Steiner RA.

Neuroendocrinology. 2004;79(5):268-77.

PMID:
15249737
14.
15.

A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.

White HS, Alex AB, Pollock A, Hen N, Shekh-Ahmad T, Wilcox KS, McDonough JH, Stables JP, Kaufmann D, Yagen B, Bialer M.

Epilepsia. 2012 Jan;53(1):134-46. doi: 10.1111/j.1528-1167.2011.03338.x. Erratum in: Epilepsia. 2012 Feb;53(2):397.

16.

Anticonvulsant activity of a nonpeptide galanin receptor agonist.

Saar K, Mazarati AM, Mahlapuu R, Hallnemo G, Soomets U, Kilk K, Hellberg S, Pooga M, Tolf BR, Shi TS, Hökfelt T, Wasterlain C, Bartfai T, Langel U.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):7136-41.

17.

Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2).

Tofighi R, Joseph B, Xia S, Xu ZQ, Hamberger B, Hökfelt T, Ceccatelli S.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2717-22. doi: 10.1073/pnas.0712300105.

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Galanin receptor 1 deletion exacerbates hippocampal neuronal loss after systemic kainate administration in mice.

Schauwecker PE.

PLoS One. 2010 Dec 13;5(12):e15657. doi: 10.1371/journal.pone.0015657.

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