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Items: 1 to 20 of 68

1.

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14164-9. doi: 10.1073/pnas.1009485107. Epub 2010 Jul 26.

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3.

Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy.

Joshi G, Gan KA, Johnson DA, Johnson JA.

Neurobiol Aging. 2015 Feb;36(2):664-79. doi: 10.1016/j.neurobiolaging.2014.09.004. Epub 2014 Sep 6.

4.

TFEB Participates in the Aβ-Induced Pathogenesis of Alzheimer's Disease by Regulating the Autophagy-Lysosome Pathway.

Zhang YD, Zhao JJ.

DNA Cell Biol. 2015 Nov;34(11):661-8. doi: 10.1089/dna.2014.2738. Epub 2015 Sep 14.

PMID:
26368054
5.

Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.

Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM.

FASEB J. 2005 Dec;19(14):2081-2. Epub 2005 Sep 26.

PMID:
16186174
6.

Aging, cortical injury and Alzheimer's disease-like pathology in the guinea pig brain.

Bates K, Vink R, Martins R, Harvey A.

Neurobiol Aging. 2014 Jun;35(6):1345-51. doi: 10.1016/j.neurobiolaging.2013.11.020. Epub 2013 Nov 27.

PMID:
24360504
7.

Alzheimer's disease.

De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.

Subcell Biochem. 2012;65:329-52. doi: 10.1007/978-94-007-5416-4_14. Review.

PMID:
23225010
8.

The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy.

Shacka JJ, Roth KA, Zhang J.

Front Biosci. 2008 Jan 1;13:718-36. Review.

PMID:
17981582
9.

Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome.

De Kimpe L, van Haastert ES, Kaminari A, Zwart R, Rutjes H, Hoozemans JJ, Scheper W.

Age (Dordr). 2013 Jun;35(3):673-87. doi: 10.1007/s11357-012-9403-0. Epub 2012 Apr 4.

10.

Expression of Ambra1 in mouse brain during physiological and Alzheimer type aging.

Sepe S, Nardacci R, Fanelli F, Rosso P, Bernardi C, Cecconi F, Mastroberardino PG, Piacentini M, Moreno S.

Neurobiol Aging. 2014 Jan;35(1):96-108. doi: 10.1016/j.neurobiolaging.2013.07.001. Epub 2013 Aug 2.

PMID:
23910655
11.

Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease.

Caccamo A, Branca C, Talboom JS, Shaw DM, Turner D, Ma L, Messina A, Huang Z, Wu J, Oddo S.

J Neurosci. 2015 Oct 14;35(41):14042-56. doi: 10.1523/JNEUROSCI.2781-15.2015.

12.

Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease.

Kukreja L, Kujoth GC, Prolla TA, Van Leuven F, Vassar R.

Mol Neurodegener. 2014 May 2;9:16. doi: 10.1186/1750-1326-9-16.

13.

P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations.

Chiu C, Miller MC, Monahan R, Osgood DP, Stopa EG, Silverberg GD.

Neurobiol Aging. 2015 Sep;36(9):2475-82. doi: 10.1016/j.neurobiolaging.2015.05.020. Epub 2015 Jun 6.

PMID:
26159621
14.

Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture.

Chen YS, Chen SD, Wu CL, Huang SS, Yang DI.

Exp Neurol. 2014 Mar;253:63-71. doi: 10.1016/j.expneurol.2013.12.009. Epub 2013 Dec 22.

PMID:
24368194
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16.

Quantitative proteomics reveals that PEA15 regulates astroglial Aβ phagocytosis in an Alzheimer's disease mouse model.

Lv J, Ma S, Zhang X, Zheng L, Ma Y, Zhao X, Lai W, Shen H, Wang Q, Ji J.

J Proteomics. 2014 Oct 14;110:45-58. doi: 10.1016/j.jprot.2014.07.028. Epub 2014 Aug 7.

PMID:
25108202
17.

Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease.

Jiang T, Yu JT, Zhu XC, Tan MS, Wang HF, Cao L, Zhang QQ, Shi JQ, Gao L, Qin H, Zhang YD, Tan L.

Pharmacol Res. 2014 Mar;81:54-63. doi: 10.1016/j.phrs.2014.02.008. Epub 2014 Mar 3.

PMID:
24602800
18.

Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?

Li X, Masliah E, Reixach N, Buxbaum JN.

J Neurosci. 2011 Aug 31;31(35):12483-90. doi: 10.1523/JNEUROSCI.2417-11.2011.

19.

Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease.

Chuang JY, Lee CW, Shih YH, Yang T, Yu L, Kuo YM.

PLoS One. 2012;7(3):e33120. doi: 10.1371/journal.pone.0033120. Epub 2012 Mar 6.

20.

Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease.

Wu ZL, Ciallella JR, Flood DG, O'Kane TM, Bozyczko-Coyne D, Savage MJ.

Neurobiol Aging. 2006 Mar;27(3):377-86. Epub 2005 May 31.

PMID:
15927307

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