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Items: 1 to 20 of 82

1.

Lessons learned from the development of oral calcitonin: the first tablet formulation of a protein in phase III clinical trials.

Karsdal MA, Henriksen K, Bay-Jensen AC, Molloy B, Arnold M, John MR, Byrjalsen I, Azria M, Riis BJ, Qvist P, Christiansen C.

J Clin Pharmacol. 2011 Apr;51(4):460-71. doi: 10.1177/0091270010372625. Epub 2010 Jul 21. Review.

PMID:
20660294
3.

Oral salmon calcitonin--pharmacology in osteoporosis.

Henriksen K, Bay-Jensen AC, Christiansen C, Karsdal MA.

Expert Opin Biol Ther. 2010 Nov;10(11):1617-29. doi: 10.1517/14712598.2010.526104. Epub 2010 Oct 11. Review.

PMID:
20932224
4.

Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin.

Karsdal MA, Byrjalsen I, Riis BJ, Christiansen C.

BMC Clin Pharmacol. 2008 Dec 4;8:12. doi: 10.1186/1472-6904-8-12.

5.

The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study.

Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Lau EM, Arnold M, Christiansen C.

Osteoarthritis Cartilage. 2010 Feb;18(2):150-9. doi: 10.1016/j.joca.2009.08.004. Epub 2009 Sep 1.

6.

Pharmacodynamics and pharmacokinetics of oral salmon calcitonin in the treatment of osteoporosis.

Bandeira L, Lewiecki EM, Bilezikian JP.

Expert Opin Drug Metab Toxicol. 2016 Jun;12(6):681-9. doi: 10.1080/17425255.2016.1175436. Epub 2016 Apr 18. Review.

PMID:
27070719
7.

A pharmacokinetic and pharmacodynamic comparison of synthetic and recombinant oral salmon calcitonin.

Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Christiansen C.

J Clin Pharmacol. 2009 Feb;49(2):229-34. doi: 10.1177/0091270008329552.

PMID:
19179298
8.

Oral calcitonin.

Hamdy RC, Daley DN.

Int J Womens Health. 2012;4:471-9. doi: 10.2147/IJWH.S24776. Epub 2012 Sep 6.

9.

Influence of food intake on the bioavailability and efficacy of oral calcitonin.

Karsdal MA, Byrjalsen I, Azria M, Arnold M, Choi L, Riis BJ, Christiansen C.

Br J Clin Pharmacol. 2009 Apr;67(4):413-20. doi: 10.1111/j.1365-2125.2009.03371.x.

10.

Lessons learned from the clinical development of oral peptides.

Karsdal MA, Riis BJ, Mehta N, Stern W, Arbit E, Christiansen C, Henriksen K.

Br J Clin Pharmacol. 2015 May;79(5):720-32. doi: 10.1111/bcp.12557. Review.

11.

A phase 3 trial of the efficacy and safety of oral recombinant calcitonin: the Oral Calcitonin in Postmenopausal Osteoporosis (ORACAL) trial.

Binkley N, Bolognese M, Sidorowicz-Bialynicka A, Vally T, Trout R, Miller C, Buben CE, Gilligan JP, Krause DS; Oral Calcitonin in Postmenopausal Osteoporosis (ORACAL) Investigators.

J Bone Miner Res. 2012 Aug;27(8):1821-9. doi: 10.1002/jbmr.1602.

12.

Oral calcitonin.

Maricic MJ.

Curr Osteoporos Rep. 2012 Mar;10(1):80-5. doi: 10.1007/s11914-011-0084-x.

PMID:
22281725
13.

Investigations of inter- and intraindividual relationships between exposure to oral salmon calcitonin and a surrogate marker of pharmacodynamic efficacy.

Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Christiansen C.

Eur J Clin Pharmacol. 2010 Jan;66(1):29-37. doi: 10.1007/s00228-009-0735-3. Epub 2009 Oct 8.

PMID:
19813008
14.

Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial.

Binkley N, Bone H, Gilligan JP, Krause DS.

Osteoporos Int. 2014 Nov;25(11):2649-56. doi: 10.1007/s00198-014-2796-0. Epub 2014 Jul 16.

15.

[Translational research on calcitonin].

Yamauchi H, Takahashi N.

Nihon Rinsho. 2005 Oct;63 Suppl 10:233-7. Review. Japanese. No abstract available.

PMID:
16279638
16.
17.

Evaluation of salmon calcitonin (sCT) enteric-coated capsule for enhanced absorption and GI tolerability in rats.

Wu L, Zhang G, Lu Q, Sun Q, Wang M, Li N, Gao Z, Sun Y, Li T, Han D, Yu X, Wang L, Sun W, Zhao D, Wu Y, Lu Y, Chen X.

Drug Dev Ind Pharm. 2010 Mar;36(3):362-70. doi: 10.1080/03639040903173580.

PMID:
19719396
18.

Evaluation of bone targeting salmon calcitonin analogues in rats developing osteoporosis and adjuvant arthritis.

Bhandari KH, Asghar W, Newa M, Jamali F, Doschak MR.

Curr Drug Deliv. 2015;12(1):98-107.

PMID:
25860966
19.

Noninvasive delivery systems for peptides and proteins in osteoporosis therapy: a retroperspective.

Hoyer H, Perera G, Bernkop-Schnürch A.

Drug Dev Ind Pharm. 2010 Jan;36(1):31-44. doi: 10.3109/03639040903059342. Review.

PMID:
19640245
20.

Pharmacokinetics of modified oral calcitonin product in healthy volunteers.

Chin CM, Gutierrez M, Still JG, Kosutic G.

Pharmacotherapy. 2004 Aug;24(8):994-1001.

PMID:
15338848

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