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Items: 1 to 20 of 73

1.

A high-throughput screen for alpha particle radiation protectants.

Seideman JH, Shum D, Djaballah H, Scheinberg DA.

Assay Drug Dev Technol. 2010 Oct;8(5):602-14. doi: 10.1089/adt.2010.0291.

2.

High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery.

Patel DA, Patel AC, Nolan WC, Zhang Y, Holtzman MJ.

PLoS One. 2012;7(5):e36594. doi: 10.1371/journal.pone.0036594.

3.

High-throughput screening normalized to biological response: application to antiviral drug discovery.

Patel DA, Patel AC, Nolan WC, Huang G, Romero AG, Charlton N, Agapov E, Zhang Y, Holtzman MJ.

J Biomol Screen. 2014 Jan;19(1):119-30. doi: 10.1177/1087057113496848.

4.

Discovery of novel scaffolds for Rho kinase 2 inhibitor through TRFRET-based high throughput screening assay.

Oh KS, Mun J, Cho JE, Lee S, Yi KY, Lim CJ, Lee JS, Park WJ, Lee BH.

Comb Chem High Throughput Screen. 2013 Jan;16(1):37-46.

PMID:
22934984
5.

The effect of dimethyl sulfoxide on the induction of DNA double-strand breaks in V79-4 mammalian cells by alpha particles.

deLara CM, Jenner TJ, Townsend KM, Marsden SJ, O'Neill P.

Radiat Res. 1995 Oct;144(1):43-9.

PMID:
7568770
6.

A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.

Mathews LA, Keller JM, Goodwin BL, Guha R, Shinn P, Mull R, Thomas CJ, de Kluyver RL, Sayers TJ, Ferrer M.

J Biomol Screen. 2012 Oct;17(9):1231-42.

PMID:
22927676
7.

Functional human 5-HT6 receptor assay for high throughput screening of chemical ligands and binding proteins.

Kim HJ, Yun HM, Kim T, Nam G, Roh EJ, Kostenis E, Choo HY, Pae AN, Rhim H.

Comb Chem High Throughput Screen. 2008 May;11(4):316-24.

PMID:
18473741
8.

AlphaLISA-based high-throughput screening assay to measure levels of soluble amyloid precursor protein α.

Wang H, Nefzi A, Fields GB, Lakshmana MK, Minond D.

Anal Biochem. 2014 Aug 15;459:24-30. doi: 10.1016/j.ab.2014.05.007.

PMID:
24857774
9.

Mechanisms of resistance to high and low linear energy transfer radiation in myeloid leukemia cells.

Haro KJ, Scott AC, Scheinberg DA.

Blood. 2012 Sep 6;120(10):2087-97. doi: 10.1182/blood-2012-01-404509.

10.

A novel high-throughput screening assay for discovery of molecules that increase cellular tetrahydrobiopterin.

Li L, Du Y, Chen W, Fu H, Harrison DG.

J Biomol Screen. 2011 Sep;16(8):836-44. doi: 10.1177/1087057111411088.

11.

High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.

Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH.

Clin Cancer Res. 2009 Dec 1;15(23):7238-45. doi: 10.1158/1078-0432.CCR-09-1964.

12.

3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen.

Li Q, Chen C, Kapadia A, Zhou Q, Harper MK, Schaack J, LaBarbera DV.

J Biomol Screen. 2011 Feb;16(2):141-54. doi: 10.1177/1087057110392995.

PMID:
21297102
13.

Redefining relative biological effectiveness in the context of the EQDX formalism: implications for alpha-particle emitter therapy.

Hobbs RF, Howell RW, Song H, Baechler S, Sgouros G.

Radiat Res. 2014 Jan;181(1):90-8. doi: 10.1667/RR13483.1.

14.

Development of a high-throughput screen for inhibitors of Epstein-Barr virus EBNA1.

Thompson S, Messick T, Schultz DC, Reichman M, Lieberman PM.

J Biomol Screen. 2010 Oct;15(9):1107-15. doi: 10.1177/1087057110379154.

15.

A dual-readout F2 assay that combines fluorescence resonance energy transfer and fluorescence polarization for monitoring bimolecular interactions.

Du Y, Nikolovska-Coleska Z, Qui M, Li L, Lewis I, Dingledine R, Stuckey JA, Krajewski K, Roller PP, Wang S, Fu H.

Assay Drug Dev Technol. 2011 Aug;9(4):382-93. doi: 10.1089/adt.2010.0292.

16.

Development and characterization of an in vitro alpha radiation exposure system.

Beaton LA, Burn TA, Stocki TJ, Chauhan V, Wilkins RC.

Phys Med Biol. 2011 Jun 21;56(12):3645-58. doi: 10.1088/0031-9155/56/12/012.

PMID:
21610295
18.

A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins.

Minuesa G, Antczak C, Shum D, Radu C, Bhinder B, Li Y, Djaballah H, Kharas MG.

Comb Chem High Throughput Screen. 2014;17(7):596-609.

19.

Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses.

Dančík V, Carrel H, Bodycombe NE, Seiler KP, Fomina-Yadlin D, Kubicek ST, Hartwell K, Shamji AF, Wagner BK, Clemons PA.

J Biomol Screen. 2014 Jun;19(5):771-81. doi: 10.1177/1087057113520226.

PMID:
24464433
20.

Cellular HTS assays for pharmacological characterization of Na(V)1.7 modulators.

Trivedi S, Dekermendjian K, Julien R, Huang J, Lund PE, Krupp J, Kronqvist R, Larsson O, Bostwick R.

Assay Drug Dev Technol. 2008 Apr;6(2):167-79.

PMID:
18078380
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