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Items: 1 to 20 of 104

1.

LRP5 is required for vascular development in deeper layers of the retina.

Xia CH, Yablonka-Reuveni Z, Gong X.

PLoS One. 2010 Jul 20;5(7):e11676. doi: 10.1371/journal.pone.0011676.

2.

Retinal expression of Wnt-pathway mediated genes in low-density lipoprotein receptor-related protein 5 (Lrp5) knockout mice.

Chen J, Stahl A, Krah NM, Seaward MR, Joyal JS, Juan AM, Hatton CJ, Aderman CM, Dennison RJ, Willett KL, Sapieha P, Smith LE.

PLoS One. 2012;7(1):e30203. doi: 10.1371/journal.pone.0030203. Epub 2012 Jan 17.

3.

Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization.

Xia CH, Lu E, Zeng J, Gong X.

PLoS One. 2013 Sep 13;8(9):e75186. doi: 10.1371/journal.pone.0075186. eCollection 2013.

4.

Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.

Huang W, Li Q, Amiry-Moghaddam M, Hokama M, Sardi SH, Nagao M, Warman ML, Olsen BR.

PLoS One. 2016 Mar 31;11(3):e0152833. doi: 10.1371/journal.pone.0152833. eCollection 2016.

5.

A model for familial exudative vitreoretinopathy caused by LPR5 mutations.

Xia CH, Liu H, Cheung D, Wang M, Cheng C, Du X, Chang B, Beutler B, Gong X.

Hum Mol Genet. 2008 Jun 1;17(11):1605-12. doi: 10.1093/hmg/ddn047. Epub 2008 Feb 9.

6.

Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.

Arnold TD, Ferrero GM, Qiu H, Phan IT, Akhurst RJ, Huang EJ, Reichardt LF.

J Neurosci. 2012 Jan 25;32(4):1197-206. doi: 10.1523/JNEUROSCI.5648-11.2012. Erratum in: J Neurosci. 2012 Apr 11;32(15):5351.

7.

Norrin stimulates cell proliferation in the superficial retinal vascular plexus and is pivotal for the recruitment of mural cells.

Zuercher J, Fritzsche M, Feil S, Mohn L, Berger W.

Hum Mol Genet. 2012 Jun 15;21(12):2619-30. doi: 10.1093/hmg/dds087. Epub 2012 Mar 6.

8.

Lrp5 functions in bone to regulate bone mass.

Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, Zambrowicz B, Gerrits H, Gossen JA, He X, Bader M, Williams BO, Warman ML, Robling AG.

Nat Med. 2011 Jun;17(6):684-91. doi: 10.1038/nm.2388. Epub 2011 May 22.

9.

Wnt signaling mediates pathological vascular growth in proliferative retinopathy.

Chen J, Stahl A, Krah NM, Seaward MR, Dennison RJ, Sapieha P, Hua J, Hatton CJ, Juan AM, Aderman CM, Willett KL, Guerin KI, Mammoto A, Campbell M, Smith LE.

Circulation. 2011 Oct 25;124(17):1871-81. doi: 10.1161/CIRCULATIONAHA.111.040337. Epub 2011 Oct 3.

10.
11.

A hybrid discrete-continuum mathematical model of pattern prediction in the developing retinal vasculature.

McDougall SR, Watson MG, Devlin AH, Mitchell CA, Chaplain MA.

Bull Math Biol. 2012 Oct;74(10):2272-314. doi: 10.1007/s11538-012-9754-9. Epub 2012 Jul 25.

PMID:
22829182
12.
13.

Pharmacologic Activation of Wnt Signaling by Lithium Normalizes Retinal Vasculature in a Murine Model of Familial Exudative Vitreoretinopathy.

Wang Z, Liu CH, Sun Y, Gong Y, Favazza TL, Morss PC, Saba NJ, Fredrick TW, He X, Akula JD, Chen J.

Am J Pathol. 2016 Oct;186(10):2588-600. doi: 10.1016/j.ajpath.2016.06.015. Epub 2016 Aug 12.

PMID:
27524797
14.

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia.

Stone J, Itin A, Alon T, Pe'er J, Gnessin H, Chan-Ling T, Keshet E.

J Neurosci. 1995 Jul;15(7 Pt 1):4738-47.

15.

Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.

Ye X, Wang Y, Cahill H, Yu M, Badea TC, Smallwood PM, Peachey NS, Nathans J.

Cell. 2009 Oct 16;139(2):285-98. doi: 10.1016/j.cell.2009.07.047. Erratum in: Cell. 2010 Apr 2;141(1):191.

16.

Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion.

Dorrell MI, Aguilar E, Friedlander M.

Invest Ophthalmol Vis Sci. 2002 Nov;43(11):3500-10.

PMID:
12407162
17.

Role of connective tissue growth factor in the retinal vasculature during development and ischemia.

Pi L, Xia H, Liu J, Shenoy AK, Hauswirth WW, Scott EW.

Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8701-10. doi: 10.1167/iovs.11-7870.

18.

Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.

Edqvist PH, Niklasson M, Vidal-Sanz M, Hallböök F, Forsberg-Nilsson K.

PLoS One. 2012;7(8):e42488. doi: 10.1371/journal.pone.0042488. Epub 2012 Aug 3.

19.

Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice.

Ohlmann A, Scholz M, Goldwich A, Chauhan BK, Hudl K, Ohlmann AV, Zrenner E, Berger W, Cvekl A, Seeliger MW, Tamm ER.

J Neurosci. 2005 Feb 16;25(7):1701-10.

20.

Differential gene expression in Ndph-knockout mice in retinal development.

Schäfer NF, Luhmann UF, Feil S, Berger W.

Invest Ophthalmol Vis Sci. 2009 Feb;50(2):906-16. doi: 10.1167/iovs.08-1731. Epub 2008 Oct 31.

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