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Items: 1 to 20 of 245

1.

ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining.

Rahal EA, Henricksen LA, Li Y, Williams RS, Tainer JA, Dixon K.

Cell Cycle. 2010 Jul 15;9(14):2866-77.

2.

A role for ATM kinase activity and Mre11 in microhomology-mediated end-joining.

Davis AJ, Chen DJ.

Cell Cycle. 2010 Aug 15;9(16):3147-8. doi: 10.4161/cc.9.16.12814. No abstract available.

PMID:
20814230
3.

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells.

Rass E, Grabarz A, Plo I, Gautier J, Bertrand P, Lopez BS.

Nat Struct Mol Biol. 2009 Aug;16(8):819-24. doi: 10.1038/nsmb.1641.

PMID:
19633668
4.

Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.

Limbo O, Moiani D, Kertokalio A, Wyman C, Tainer JA, Russell P.

Nucleic Acids Res. 2012 Dec;40(22):11435-49. doi: 10.1093/nar/gks954.

5.

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW.

Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604.

6.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
7.

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.

Truong LN, Li Y, Shi LZ, Hwang PY, He J, Wang H, Razavian N, Berns MW, Wu X.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7720-5. doi: 10.1073/pnas.1213431110.

8.

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Review.

PMID:
21036673
9.

The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.

Yu Z, Vogel G, Coulombe Y, Dubeau D, Spehalski E, Hébert J, Ferguson DO, Masson JY, Richard S.

Cell Res. 2012 Feb;22(2):305-20. doi: 10.1038/cr.2011.128.

10.

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.

Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO.

Cell. 2008 Oct 3;135(1):85-96. doi: 10.1016/j.cell.2008.08.015.

11.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016.

PMID:
19583974
12.
13.

Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.

Lee JH, Mand MR, Deshpande RA, Kinoshita E, Yang SH, Wyman C, Paull TT.

J Biol Chem. 2013 May 3;288(18):12840-51. doi: 10.1074/jbc.M113.460378.

14.

DNA-PKcs and ATM co-regulate DNA double-strand break repair.

Shrivastav M, Miller CA, De Haro LP, Durant ST, Chen BP, Chen DJ, Nickoloff JA.

DNA Repair (Amst). 2009 Aug 6;8(8):920-9. doi: 10.1016/j.dnarep.2009.05.006.

15.

ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks.

Bennardo N, Stark JM.

PLoS Genet. 2010 Nov 4;6(11):e1001194. doi: 10.1371/journal.pgen.1001194.

16.

Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability.

Stracker TH, Williams BR, Deriano L, Theunissen JW, Adelman CA, Roth DB, Petrini JH.

Mol Cell Biol. 2009 Jan;29(2):503-14. doi: 10.1128/MCB.01354-08.

17.

DNA end resection is needed for the repair of complex lesions in G1-phase human cells.

Averbeck NB, Ringel O, Herrlitz M, Jakob B, Durante M, Taucher-Scholz G.

Cell Cycle. 2014;13(16):2509-16. doi: 10.4161/15384101.2015.941743.

18.

ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.

Lavin MF.

Oncogene. 2007 Dec 10;26(56):7749-58. Review.

PMID:
18066087
19.

Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

Williams RS, Williams JS, Tainer JA.

Biochem Cell Biol. 2007 Aug;85(4):509-20. Review.

PMID:
17713585
20.

Artemis links ATM to double strand break rejoining.

Jeggo PA, Löbrich M.

Cell Cycle. 2005 Mar;4(3):359-62. Review.

PMID:
15684609
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