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Items: 1 to 20 of 129

1.

A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation.

Peltonen HM, Akerman KE, Bart G.

Biochim Biophys Acta. 2010 Oct;1803(10):1206-12. doi: 10.1016/j.bbamcr.2010.07.001. Epub 2010 Jul 16.

2.

Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation.

Xu TR, Ward RJ, Pediani JD, Milligan G.

J Biol Chem. 2012 Apr 27;287(18):14937-49. doi: 10.1074/jbc.M111.334300. Epub 2012 Mar 2.

3.

Dynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptor.

Duguay D, Bélanger-Nelson E, Mongrain V, Beben A, Khatchadourian A, Cermakian N.

PLoS One. 2011;6(10):e26430. doi: 10.1371/journal.pone.0026430. Epub 2011 Oct 20.

4.

The signalling profile of recombinant human orexin-2 receptor.

Tang J, Chen J, Ramanjaneya M, Punn A, Conner AC, Randeva HS.

Cell Signal. 2008 Sep;20(9):1651-61. doi: 10.1016/j.cellsig.2008.05.010. Epub 2008 May 27.

PMID:
18599270
5.

Hypocretin/orexin increases the expression of steroidogenic enzymes in human adrenocortical NCI H295R cells.

Wenzel J, Grabinski N, Knopp CA, Dendorfer A, Ramanjaneya M, Randeva HS, Ehrhart-Bornstein M, Dominiak P, Jöhren O.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1601-9. doi: 10.1152/ajpregu.91034.2008. Epub 2009 Sep 30.

6.

The hypocretins are weak agonists at recombinant human orexin-1 and orexin-2 receptors.

Smart D, Jerman JC, Brough SJ, Neville WA, Jewitt F, Porter RA.

Br J Pharmacol. 2000 Apr;129(7):1289-91.

7.

OX1 orexin/hypocretin receptor activation of phospholipase D.

Jäntti MH, Putula J, Somerharju P, Frohman MA, Kukkonen JP.

Br J Pharmacol. 2012 Feb;165(4b):1109-23. doi: 10.1111/j.1476-5381.2011.01565.x.

8.

Involvement of TRPC3 channels in calcium oscillations mediated by OX(1) orexin receptors.

Peltonen HM, Magga JM, Bart G, Turunen PM, Antikainen MS, Kukkonen JP, Akerman KE.

Biochem Biophys Res Commun. 2009 Jul 31;385(3):408-12. doi: 10.1016/j.bbrc.2009.05.077. Epub 2009 May 21.

PMID:
19464259
9.

Orexin-induced apoptosis: the key role of the seven-transmembrane domain orexin type 2 receptor.

Voisin T, Firar AE, Avondo V, Laburthe M.

Endocrinology. 2006 Oct;147(10):4977-84. Epub 2006 Jul 20.

PMID:
16857748
10.

G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase.

Ammoun S, Lindholm D, Wootz H, Akerman KE, Kukkonen JP.

J Biol Chem. 2006 Jan 13;281(2):834-42. Epub 2005 Nov 10.

11.

Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR.

Smart D, Jerman JC, Brough SJ, Rushton SL, Murdock PR, Jewitt F, Elshourbagy NA, Ellis CE, Middlemiss DN, Brown F.

Br J Pharmacol. 1999 Sep;128(1):1-3.

12.

Orexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons.

Sasson R, Dearth RK, White RS, Chappell PE, Mellon PL.

Neuroendocrinology. 2006;84(6):353-63. Epub 2006 Dec 28.

13.

Heteromultimerization of cannabinoid CB(1) receptor and orexin OX(1) receptor generates a unique complex in which both protomers are regulated by orexin A.

Ward RJ, Pediani JD, Milligan G.

J Biol Chem. 2011 Oct 28;286(43):37414-28. doi: 10.1074/jbc.M111.287649. Epub 2011 Sep 9.

14.

Orexin-stimulated MAP kinase cascades are activated through multiple G-protein signalling pathways in human H295R adrenocortical cells: diverse roles for orexins A and B.

Ramanjaneya M, Conner AC, Chen J, Kumar P, Brown JE, Jöhren O, Lehnert H, Stanfield PR, Randeva HS.

J Endocrinol. 2009 Aug;202(2):249-61. doi: 10.1677/JOE-08-0536. Epub 2009 May 21.

15.

Agonist potency differentiates G protein activation and Ca2+ signalling by the orexin receptor type 1.

Magga J, Bart G, Oker-Blom C, Kukkonen JP, Akerman KE, Näsman J.

Biochem Pharmacol. 2006 Mar 14;71(6):827-36. Epub 2006 Jan 20.

PMID:
16430869
16.

The Neuropeptide Orexin-A Inhibits the GABAA Receptor by PKC and Ca2+/CaMKII-Dependent Phosphorylation of Its β1 Subunit.

Sachidanandan D, Reddy HP, Mani A, Hyde GJ, Bera AK.

J Mol Neurosci. 2017 Apr;61(4):459-467. doi: 10.1007/s12031-017-0886-0. Epub 2017 Jan 19.

PMID:
28105535
17.

Orexin/hypocretin receptor chimaeras reveal structural features important for orexin peptide distinction.

Putula J, Turunen PM, Johansson L, Näsman J, Ra R, Korhonen L, Kukkonen JP.

FEBS Lett. 2011 May 6;585(9):1368-74. doi: 10.1016/j.febslet.2011.04.020. Epub 2011 Apr 15.

18.

Requirement of intact disulfide bonds in orexin-A-induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation.

Okumura T, Takeuchi S, Motomura W, Yamada H, Egashira Si S, Asahi S, Kanatani A, Ihara M, Kohgo Y.

Biochem Biophys Res Commun. 2001 Feb 2;280(4):976-81.

PMID:
11162621
19.

Orexin receptor subtype activation and locomotor behaviour in the rat.

Samson WK, Bagley SL, Ferguson AV, White MM.

Acta Physiol (Oxf). 2010 Mar;198(3):313-24. doi: 10.1111/j.1748-1716.2009.02056.x. Epub 2009 Nov 4.

20.

Study of orexins signal transduction pathways in rat olfactory mucosa and in olfactory sensory neurons-derived cell line Odora: multiple orexin signalling pathways.

Gorojankina T, Grébert D, Salesse R, Tanfin Z, Caillol M.

Regul Pept. 2007 Jun 7;141(1-3):73-85. Epub 2007 Jan 3.

PMID:
17292491

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