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Items: 1 to 20 of 106

1.

A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivo.

Chen C, Zhao X, Kierzek R, Yu YT.

Mol Cell Biol. 2010 Sep;30(17):4108-19. doi: 10.1128/MCB.00531-10. Epub 2010 Jul 6.

3.

Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M.

Nature. 2011 Jul 13;475(7356):408-11. doi: 10.1038/nature10171.

PMID:
21753750
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A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts.

Sridharan V, Singh R.

Mol Cell Biol. 2007 Oct;27(20):7334-44. Epub 2007 Aug 20.

6.

U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.

Jenkins JL, Agrawal AA, Gupta A, Green MR, Kielkopf CL.

Nucleic Acids Res. 2013 Apr 1;41(6):3859-73. doi: 10.1093/nar/gkt046. Epub 2013 Feb 1.

7.

Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.

Sickmier EA, Frato KE, Shen H, Paranawithana SR, Green MR, Kielkopf CL.

Mol Cell. 2006 Jul 7;23(1):49-59.

9.

Functional recognition of the 3' splice site AG by the splicing factor U2AF35.

Wu S, Romfo CM, Nilsen TW, Green MR.

Nature. 1999 Dec 16;402(6763):832-5.

PMID:
10617206
10.

Dual function for U2AF(35) in AG-dependent pre-mRNA splicing.

Guth S, Tange TØ, Kellenberger E, Valcárcel J.

Mol Cell Biol. 2001 Nov;21(22):7673-81.

11.

In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site.

Pacheco TR, Coelho MB, Desterro JM, Mollet I, Carmo-Fonseca M.

Mol Cell Biol. 2006 Nov;26(21):8183-90. Epub 2006 Aug 28.

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The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.

Valcárcel J, Singh R, Zamore PD, Green MR.

Nature. 1993 Mar 11;362(6416):171-5.

PMID:
7680770
18.

Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected].

Valcárcel J, Gaur RK, Singh R, Green MR.

Science. 1996 Sep 20;273(5282):1706-9. Erratum in: Science 1996 Oct 4;274(5284):21.

PMID:
8781232
19.

Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins.

Singh R, Valcárcel J, Green MR.

Science. 1995 May 26;268(5214):1173-6.

PMID:
7761834
20.

Signal-regulated Pre-mRNA occupancy by the general splicing factor U2AF.

Tisserant A, König H.

PLoS One. 2008 Jan 9;3(1):e1418. doi: 10.1371/journal.pone.0001418.

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