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Items: 1 to 20 of 52

1.

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine.

Cadwell K, Patel KK, Maloney NS, Liu TC, Ng AC, Storer CE, Head RD, Xavier R, Stappenbeck TS, Virgin HW.

Cell. 2010 Jun 25;141(7):1135-45. doi: 10.1016/j.cell.2010.05.009.

2.

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.

Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th.

Nature. 2008 Nov 13;456(7219):259-63. doi: 10.1038/nature07416. Epub 2008 Oct 5.

3.

Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease.

Deuring JJ, Fuhler GM, Konstantinov SR, Peppelenbosch MP, Kuipers EJ, de Haar C, van der Woude CJ.

Gut. 2014 Jul;63(7):1081-91. doi: 10.1136/gutjnl-2012-303527. Epub 2013 Aug 20.

PMID:
23964099
4.

Decoding norovirus infection in Crohn's disease.

Chamaillard M, Cesaro A, Lober PE, Hober D.

Inflamm Bowel Dis. 2014 Apr;20(4):767-70. doi: 10.1097/01.MIB.0000440613.83703.4a. Review.

PMID:
24351661
5.

Crohn's disease: Genes, viruses and microbes.

Simmons A.

Nature. 2010 Aug 5;466(7307):699-700. doi: 10.1038/466699a. No abstract available.

PMID:
20686558
6.

ATG16L1 Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells.

Kaser A, Blumberg RS.

Gut. 2014 Jul;63(7):1038-9. doi: 10.1136/gutjnl-2013-306103. Epub 2013 Dec 4. No abstract available.

7.

Crohn's disease and the NOD2 gene: a role for paneth cells.

Lala S, Ogura Y, Osborne C, Hor SY, Bromfield A, Davies S, Ogunbiyi O, Nuñez G, Keshav S.

Gastroenterology. 2003 Jul;125(1):47-57.

PMID:
12851870
8.

Viruses, autophagy genes, and Crohn's disease.

Hubbard VM, Cadwell K.

Viruses. 2011 Jul;3(7):1281-311. doi: 10.3390/v3071281. Epub 2011 Jul 21. Review.

9.

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis.

Ogura Y, Lala S, Xin W, Smith E, Dowds TA, Chen FF, Zimmermann E, Tretiakova M, Cho JH, Hart J, Greenson JK, Keshav S, Nuñez G.

Gut. 2003 Nov;52(11):1591-7.

10.

Paneth Cell Alterations in the Development and Phenotype of Crohn's Disease.

Stappenbeck TS, McGovern DP.

Gastroenterology. 2017 Feb;152(2):322-326. doi: 10.1053/j.gastro.2016.10.003. Epub 2016 Oct 8.

PMID:
27729212
11.

A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.

Cadwell K, Patel KK, Komatsu M, Virgin HW 4th, Stappenbeck TS.

Autophagy. 2009 Feb;5(2):250-2. Epub 2009 Feb 8.

12.

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression.

Wehkamp J, Harder J, Weichenthal M, Schwab M, Schäffeler E, Schlee M, Herrlinger KR, Stallmach A, Noack F, Fritz P, Schröder JM, Bevins CL, Fellermann K, Stange EF.

Gut. 2004 Nov;53(11):1658-64.

13.

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2008 Mar;103(3):682-91. Epub 2007 Dec 20.

PMID:
18162085
14.

Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease.

Koslowski MJ, Kübler I, Chamaillard M, Schaeffeler E, Reinisch W, Wang G, Beisner J, Teml A, Peyrin-Biroulet L, Winter S, Herrlinger KR, Rutgeerts P, Vermeire S, Cooney R, Fellermann K, Jewell D, Bevins CL, Schwab M, Stange EF, Wehkamp J.

PLoS One. 2009;4(2):e4496. doi: 10.1371/journal.pone.0004496. Epub 2009 Feb 16.

15.

Crohn's disease, autophagy, and the Paneth cell.

Klionsky DJ.

N Engl J Med. 2009 Apr 23;360(17):1785-6. doi: 10.1056/NEJMcibr0810347. Epub 2009 Apr 15. No abstract available.

16.

Understanding gene-environment interactions in a mouse model of Crohn's disease.

Duckworth CA.

Dis Model Mech. 2011 Jan;4(1):7-8. doi: 10.1242/dmm.007120. No abstract available.

17.

Evidence of expression variation and allelic imbalance in Crohn's disease susceptibility genes NOD2 and ATG16L1 in human dendritic cells.

Hu J, Peter I.

Gene. 2013 Sep 25;527(2):496-502. doi: 10.1016/j.gene.2013.06.066. Epub 2013 Jul 10.

18.

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration.

Tschurtschenthaler M, Wang J, Fricke C, Fritz TM, Niederreiter L, Adolph TE, Sarcevic E, Künzel S, Offner FA, Kalinke U, Baines JF, Tilg H, Kaser A.

Gut. 2014 Dec;63(12):1921-31. doi: 10.1136/gutjnl-2013-305863. Epub 2014 Feb 20.

PMID:
24555997
19.

Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort.

Weersma RK, Stokkers PC, van Bodegraven AA, van Hogezand RA, Verspaget HW, de Jong DJ, van der Woude CJ, Oldenburg B, Linskens RK, Festen EA, van der Steege G, Hommes DW, Crusius JB, Wijmenga C, Nolte IM, Dijkstra G; Dutch Initiative on Crohn and Colitis (ICC).

Gut. 2009 Mar;58(3):388-95. doi: 10.1136/gut.2007.144865. Epub 2008 Sep 29.

PMID:
18824555
20.

Autophagy gives a nod and a wink to the inflammasome and Paneth cells in Crohn's disease.

Deretic V, Master S, Singh S.

Dev Cell. 2008 Nov;15(5):641-2. doi: 10.1016/j.devcel.2008.10.009.

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