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Items: 1 to 20 of 123


High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC.

Sun P, Lin DH, Yue P, Jiang H, Gotlinger KH, Schwartzman ML, Falck JR, Goli M, Wang WH.

J Am Soc Nephrol. 2010 Oct;21(10):1667-77. doi: 10.1681/ASN.2009111110. Epub 2010 Jul 1.


Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways.

Wei Y, Lin DH, Kemp R, Yaddanapudi GS, Nasjletti A, Falck JR, Wang WH.

J Gen Physiol. 2004 Dec;124(6):719-27. Epub 2004 Nov 15.


Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC.

Sun P, Lin DH, Wang T, Babilonia E, Wang Z, Jin Y, Kemp R, Nasjletti A, Wang WH.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1192-200. Epub 2006 Jul 18.


Epoxyeicosatrienoic acid activates BK channels in the cortical collecting duct.

Sun P, Liu W, Lin DH, Yue P, Kemp R, Satlin LM, Wang WH.

J Am Soc Nephrol. 2009 Mar;20(3):513-23. doi: 10.1681/ASN.2008040427. Epub 2008 Dec 10.


Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC).

Pavlov TS, Ilatovskaya DV, Levchenko V, Mattson DL, Roman RJ, Staruschenko A.

Am J Physiol Renal Physiol. 2011 Sep;301(3):F672-81. doi: 10.1152/ajprenal.00597.2010. Epub 2011 Jun 22.


Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.

Wang WH, Zhang C, Lin DH, Wang L, Graves JP, Zeldin DC, Capdevila JH.

Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F453-60. doi: 10.1152/ajprenal.00123.2014. Epub 2014 Jun 25.


Arachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenase-dependent metabolic pathways.

Wang Z, Wei Y, Falck JR, Atcha KR, Wang WH.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1441-7. doi: 10.1152/ajprenal.00038.2008. Epub 2008 Apr 16.


Adenosine inhibits ENaC via cytochrome P-450 epoxygenase-dependent metabolites of arachidonic acid.

Wei Y, Sun P, Wang Z, Yang B, Carroll MA, Wang WH.

Am J Physiol Renal Physiol. 2006 May;290(5):F1163-8. Epub 2005 Oct 18.


Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake.

Sun P, Antoun J, Lin DH, Yue P, Gotlinger KH, Capdevila J, Wang WH.

Hypertension. 2012 Feb;59(2):339-47. doi: 10.1161/HYPERTENSIONAHA.111.178475. Epub 2011 Dec 19.


Role of cytochrome P450 epoxygenase in regulating renal membrane transport and hypertension.

Capdevila J, Wang W.

Curr Opin Nephrol Hypertens. 2013 Mar;22(2):163-9. doi: 10.1097/MNH.0b013e32835d911e. Review.


Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles.

Gauthier KM, Olson L, Harder A, Isbell M, Imig JD, Gutterman DD, Falck JR, Campbell WB.

Am J Physiol Renal Physiol. 2011 Oct;301(4):F765-72. doi: 10.1152/ajprenal.00201.2011. Epub 2011 Jul 13.


Regulation of potassium channels in coronary smooth muscle by adenoviral expression of cytochrome P-450 epoxygenase.

Campbell WB, Holmes BB, Falck JR, Capdevila JH, Gauthier KM.

Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H64-71. Epub 2005 Sep 2.


Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms.

Lu T, Ye D, Wang X, Seubert JM, Graves JP, Bradbury JA, Zeldin DC, Lee HC.

J Physiol. 2006 Sep 1;575(Pt 2):627-44. Epub 2006 Jun 22.


Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation.

Pidkovka N, Rao R, Mei S, Gong Y, Harris RC, Wang WH, Capdevila JH.

J Biol Chem. 2013 Feb 15;288(7):5223-31. doi: 10.1074/jbc.M112.407981. Epub 2013 Jan 2.


Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats.

Yousif MH, Benter IF.

Vascul Pharmacol. 2007 Nov-Dec;47(5-6):281-7. Epub 2007 Aug 16.


Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids.

Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL.

Circ Res. 2000 Nov 24;87(11):992-8.


Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease.

Theken KN, Schuck RN, Edin ML, Tran B, Ellis K, Bass A, Lih FB, Tomer KB, Poloyac SM, Wu MC, Hinderliter AL, Zeldin DC, Stouffer GA, Lee CR.

Atherosclerosis. 2012 Jun;222(2):530-6. doi: 10.1016/j.atherosclerosis.2012.03.022. Epub 2012 Mar 27.


Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney.

Sun P, Yue P, Wang WH.

Am J Physiol Renal Physiol. 2012 Mar 15;302(6):F679-87. doi: 10.1152/ajprenal.00368.2011. Epub 2011 Dec 14.


Regulation of forskolin-induced cAMP production by cytochrome P450 epoxygenase metabolites of arachidonic acid in HEK293 cells.

Abukhashim M, Wiebe GJ, Seubert JM.

Cell Biol Toxicol. 2011 Oct;27(5):321-32. doi: 10.1007/s10565-011-9190-x. Epub 2011 Apr 26.


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