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Items: 1 to 20 of 101

1.

A novel, broad-spectrum anticancer compound containing the imidazo[4,5-e][1,3]diazepine ring system.

Xie M, Ujjinamatada RK, Sadowska M, Lapidus RG, Edelman MJ, Hosmane RS.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4386-9. doi: 10.1016/j.bmcl.2010.06.061. Epub 2010 Jun 15.

2.

Potent in vitro anticancer activities of ring-expanded ("fat") nucleosides containing the imidazo[4,5-e][1,3]diazepine ring system.

Gill JK, Wang L, Bretner M, Newman R, Kyprianou N, Hosmane RS.

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1043-5.

PMID:
11562954
3.

Structure-based drug design and potent anti-cancer activity of tricyclic 5:7:5-fused diimidazo[4,5-d:4',5'-f][1,3]diazepines.

Kondaskar A, Kondaskar S, Fishbein JC, Carter-Cooper BA, Lapidus RG, Sadowska M, Edelman MJ, Hosmane RS.

Bioorg Med Chem. 2013 Feb 1;21(3):618-31. doi: 10.1016/j.bmc.2012.11.050. Epub 2012 Dec 11.

4.

Imidazopyridine-fused [1,3]-diazepinones: synthesis and antiproliferative activity.

Gallud A, Vaillant O, Maillard LT, Arama DP, Dubois J, Maynadier M, Lisowski V, Garcia M, Martinez J, Masurier N.

Eur J Med Chem. 2014 Mar 21;75:382-90. doi: 10.1016/j.ejmech.2014.01.044. Epub 2014 Jan 30.

PMID:
24561668
5.

Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.

Varvaresou A, Iakovou K, Gikas E, Fichtner I, Fiebig HH, Kelland LR, Double JA, Bibby MC, Hendriks HR.

Anticancer Res. 2004 Mar-Apr;24(2B):907-19.

6.

Synthesis and biological evaluation of new securinine analogues as potential anticancer agents.

Perez M, Ayad T, Maillos P, Poughon V, Fahy J, Ratovelomanana-Vidal V.

Eur J Med Chem. 2016 Feb 15;109:287-93. doi: 10.1016/j.ejmech.2016.01.007. Epub 2016 Jan 12.

PMID:
26793989
7.

Synthesis and anticancer activities of ageladine A and structural analogs.

Ma Y, Nam S, Jove R, Yakushijin K, Horne DA.

Bioorg Med Chem Lett. 2010 Jan 1;20(1):83-6. doi: 10.1016/j.bmcl.2009.11.036. Epub 2009 Nov 14.

8.

Synthesis and antiproliferative activity of novel polynuclear heterocyclic compounds derived from 2,3-diaminophenazine.

Mahran AM, Ragab SSh, Hashem AI, Ali MM, Nada AA.

Eur J Med Chem. 2015 Jan 27;90:568-76. doi: 10.1016/j.ejmech.2013.12.007. Epub 2013 Dec 16.

PMID:
25497130
9.

Androgen receptor antagonists and anti-prostate cancer activities of some synthesized steroidal candidates.

Bahashwan SA, Al-Omar MA, Ezzeldin E, Abdalla MM, Fayed AA, Amr AG.

Chem Pharm Bull (Tokyo). 2011;59(11):1363-8.

10.
11.

Solvent-free, microwave assisted synthesis of polyhalo heterocyclic ketene aminals as novel anti-cancer agents.

Yan SJ, Huang C, Zeng XH, Huang R, Lin J.

Bioorg Med Chem Lett. 2010 Jan 1;20(1):48-51. doi: 10.1016/j.bmcl.2009.11.044. Epub 2009 Nov 16.

PMID:
19948403
12.

Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors.

Zhang YB, Wang XL, Liu W, Yang YS, Tang JF, Zhu HL.

Bioorg Med Chem. 2012 Nov 1;20(21):6356-65. doi: 10.1016/j.bmc.2012.08.059. Epub 2012 Sep 11.

PMID:
23018096
13.

Fluoroalkane thioheterocyclic derivatives and their antitumor activity.

Li G, Sun Q, Wang D, Xu Y, Zhuang J, Zhang Q, Sun D.

Eur J Med Chem. 2015 Mar 26;93:423-30. doi: 10.1016/j.ejmech.2015.02.031. Epub 2015 Feb 20.

PMID:
25728023
14.

Synthesis and antitumour activities of a novel class of dehydroabietylamine derivatives.

Chen Y, Lin ZX, Zhou AM.

Nat Prod Res. 2012;26(23):2188-95. doi: 10.1080/14786419.2011.648191. Epub 2012 Jan 11.

PMID:
22235912
15.
16.

Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents.

Wang X, Nakagawa-Goto K, Bastow KF, Don MJ, Lin YL, Wu TS, Lee KH.

J Med Chem. 2006 Sep 7;49(18):5631-4.

PMID:
16942038
17.

A novel, broad-spectrum antitumor compound containing the 1-hydroxycyclohexa-2,5-dien-4-one group: the disclosure of a new antitumor pharmacophore in protoapigenone 1.

Yuan Q, Liu Z, Xiong C, Wu L, Wang J, Ruan J.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3427-30. doi: 10.1016/j.bmcl.2011.03.108. Epub 2011 Apr 5.

PMID:
21515048
18.

Synthesis, anticancer activity, and SAR analyses of compounds containing the 5:7-fused 4,6,8-triaminoimidazo[4,5-e][1,3]diazepine ring system.

Xie M, Lapidus RG, Sadowska M, Edelman MJ, Hosmane RS.

Bioorg Med Chem. 2016 Jun 15;24(12):2595-602. doi: 10.1016/j.bmc.2016.03.015. Epub 2016 Mar 9.

PMID:
27134120
19.

Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation.

Hill TA, Stewart SG, Ackland SP, Gilbert J, Sauer B, Sakoff JA, McCluskey A.

Bioorg Med Chem. 2007 Sep 15;15(18):6126-34. Epub 2007 Jun 20.

PMID:
17606377
20.

Synthesis and antitumor activity evaluation of new 2-(4-aminophenyl)benzothiazole derivatives bearing different heterocyclic rings.

Yurttaş L, Tay F, Demirayak Ş.

J Enzyme Inhib Med Chem. 2015 Jun;30(3):458-65. doi: 10.3109/14756366.2014.945168. Epub 2014 Sep 8.

PMID:
25198890

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