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Items: 1 to 20 of 108

1.

Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior.

Mukherjee S, Coque L, Cao JL, Kumar J, Chakravarty S, Asaithamby A, Graham A, Gordon E, Enwright JF 3rd, DiLeone RJ, Birnbaum SG, Cooper DC, McClung CA.

Biol Psychiatry. 2010 Sep 15;68(6):503-11. doi: 10.1016/j.biopsych.2010.04.031. Epub 2010 Jun 29.

2.

Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 mouse model of mania.

Coque L, Mukherjee S, Cao JL, Spencer S, Marvin M, Falcon E, Sidor MM, Birnbaum SG, Graham A, Neve RL, Gordon E, Ozburn AR, Goldberg MS, Han MH, Cooper DC, McClung CA.

Neuropsychopharmacology. 2011 Jun;36(7):1478-88. doi: 10.1038/npp.2011.33. Epub 2011 Mar 23.

3.

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.

Sidor MM, Spencer SM, Dzirasa K, Parekh PK, Tye KM, Warden MR, Arey RN, Enwright JF 3rd, Jacobsen JP, Kumar S, Remillard EM, Caron MG, Deisseroth K, McClung CA.

Mol Psychiatry. 2015 Nov;20(11):1406-19. doi: 10.1038/mp.2014.167. Epub 2015 Jan 6. Erratum in: Mol Psychiatry. 2015 Nov;20(11):1479-80.

4.

Mania-like behavior induced by disruption of CLOCK.

Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA Jr, McClung CA.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6406-11. Epub 2007 Mar 22.

5.

An important role for cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors.

Arey RN, Enwright JF 3rd, Spencer SM, Falcon E, Ozburn AR, Ghose S, Tamminga C, McClung CA.

Mol Psychiatry. 2014 Mar;19(3):342-50. doi: 10.1038/mp.2013.12. Epub 2013 Feb 12. Erratum in: Mol Psychiatry. 2014 Mar;19(3):400.

6.

The role of clock in ethanol-related behaviors.

Ozburn AR, Falcon E, Mukherjee S, Gillman A, Arey R, Spencer S, McClung CA.

Neuropsychopharmacology. 2013 Nov;38(12):2393-400. doi: 10.1038/npp.2013.138. Epub 2013 May 31.

7.

Further evidence for ClockΔ19 mice as a model for bipolar disorder mania using cross-species tests of exploration and sensorimotor gating.

van Enkhuizen J, Minassian A, Young JW.

Behav Brain Res. 2013 Jul 15;249:44-54. doi: 10.1016/j.bbr.2013.04.023. Epub 2013 Apr 23.

8.

Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment.

Schnell A, Sandrelli F, Ranc V, Ripperger JA, Brai E, Alberi L, Rainer G, Albrecht U.

Chronobiol Int. 2015;32(8):1075-89. doi: 10.3109/07420528.2015.1062024. Epub 2015 Aug 28.

PMID:
26317159
9.

High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.

Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X, Garcia M, Peters EC, Etchegaray JP, Traver D, Schultz PG, Kay SA.

PLoS Biol. 2010 Dec 14;8(12):e1000559. doi: 10.1371/journal.pbio.1000559.

10.

Inborn differences in environmental reactivity predict divergent diurnal behavioral, endocrine, and gene expression rhythms.

Kerman IA, Clinton SM, Simpson DN, Bedrosian TA, Bernard R, Akil H, Watson SJ.

Psychoneuroendocrinology. 2012 Feb;37(2):256-69. doi: 10.1016/j.psyneuen.2011.06.010. Epub 2011 Jul 20.

11.

Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors.

Zhong P, Liu X, Zhang Z, Hu Y, Liu SJ, Lezama-Ruiz M, Joksimovic M, Liu QS.

J Neurosci. 2014 Apr 30;34(18):6352-66. doi: 10.1523/JNEUROSCI.3673-13.2014.

12.

Calcium channel genes associated with bipolar disorder modulate lithium's amplification of circadian rhythms.

McCarthy MJ, Le Roux MJ, Wei H, Beesley S, Kelsoe JR, Welsh DK.

Neuropharmacology. 2016 Feb;101:439-48. doi: 10.1016/j.neuropharm.2015.10.017. Epub 2015 Oct 22.

13.

Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood.

Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz S, Brunk I, Spanagel R, Ahnert-Hilger G, Meijer JH, Albrecht U.

Curr Biol. 2008 May 6;18(9):678-83. doi: 10.1016/j.cub.2008.04.012. Epub 2008 Apr 24.

14.

Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation.

Chung S, Lee EJ, Yun S, Choe HK, Park SB, Son HJ, Kim KS, Dluzen DE, Lee I, Hwang O, Son GH, Kim K.

Cell. 2014 May 8;157(4):858-68. doi: 10.1016/j.cell.2014.03.039.

15.

Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.

Shimomura K, Kumar V, Koike N, Kim TK, Chong J, Buhr ED, Whiteley AR, Low SS, Omura C, Fenner D, Owens JR, Richards M, Yoo SH, Hong HK, Vitaterna MH, Bass J, Pletcher MT, Wiltshire T, Hogenesch J, Lowrey PL, Takahashi JS.

Elife. 2013 Apr 9;2:e00426. doi: 10.7554/eLife.00426.

16.

Role for the Clock gene in bipolar disorder.

McClung CA.

Cold Spring Harb Symp Quant Biol. 2007;72:637-44. doi: 10.1101/sqb.2007.72.031. Review.

PMID:
18419323
17.

Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice.

Lasek AW, Janak PH, He L, Whistler JL, Heberlein U.

Genes Brain Behav. 2007 Nov;6(8):728-35. Epub 2007 Mar 26.

18.

Diurnal expression of the thrombopoietin gene is regulated by CLOCK.

Tracey CJ, Pan X, Catterson JH, Harmar AJ, Hussain MM, Hartley PS.

J Thromb Haemost. 2012 Apr;10(4):662-9. doi: 10.1111/j.1538-7836.2012.04643.x.

19.

An inhibitor of casein kinase 1 ε/δ partially normalizes the manic-like behaviors of the ClockΔ19 mouse.

Arey R, McClung CA.

Behav Pharmacol. 2012 Aug;23(4):392-6. doi: 10.1097/FBP.0b013e32835651fd.

20.

Regulation of dopaminergic transmission and cocaine reward by the Clock gene.

McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9377-81. Epub 2005 Jun 20.

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