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Items: 1 to 20 of 95

1.

Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer.

Lo PK, Lee JS, Liang X, Han L, Mori T, Fackler MJ, Sadik H, Argani P, Pandita TK, Sukumar S.

Cancer Res. 2010 Jul 15;70(14):6047-58. doi: 10.1158/0008-5472.CAN-10-1576. Epub 2010 Jun 29.

2.

The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.

Lo PK, Lee JS, Sukumar S.

Cell Signal. 2012 Jan;24(1):316-24. doi: 10.1016/j.cellsig.2011.09.017. Epub 2011 Sep 22.

3.

Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas.

Lo PK, Lee JS, Chen H, Reisman D, Berger FG, Sukumar S.

Exp Mol Pathol. 2013 Feb;94(1):262-9. doi: 10.1016/j.yexmp.2012.10.014. Epub 2012 Oct 24.

4.

Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer.

Wolf I, Bose S, Desmond JC, Lin BT, Williamson EA, Karlan BY, Koeffler HP.

Breast Cancer Res Treat. 2007 Oct;105(2):139-55. Epub 2007 Feb 13.

PMID:
17295047
6.

Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis.

Wang Y, Shenouda S, Baranwal S, Rathinam R, Jain P, Bao L, Hazari S, Dash S, Alahari SK.

Mol Cancer. 2011 Jul 13;10:84. doi: 10.1186/1476-4598-10-84.

7.

Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.

Borges S, Döppler H, Perez EA, Andorfer CA, Sun Z, Anastasiadis PZ, Thompson E, Geiger XJ, Storz P.

Breast Cancer Res. 2013 Aug 23;15(2):R66. doi: 10.1186/bcr3460.

8.

HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins.

Jung KH, Noh JH, Kim JK, Eun JW, Bae HJ, Xie HJ, Chang YG, Kim MG, Park H, Lee JY, Nam SW.

J Cell Biochem. 2012 Jun;113(6):2167-77. doi: 10.1002/jcb.24090.

PMID:
22492270
9.

Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease.

Johnson JL, Pillai S, Pernazza D, Sebti SM, Lawrence NJ, Chellappan SP.

Cancer Res. 2012 Jan 15;72(2):516-26. doi: 10.1158/0008-5472.CAN-11-2647. Epub 2011 Nov 15. Erratum in: Cancer Res. 2012 Mar 1;72(5):1317.

10.

Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis.

Shen WH, Yin Y, Broussard SR, McCusker RH, Freund GG, Dantzer R, Kelley KW.

J Biol Chem. 2004 Feb 27;279(9):7438-46. Epub 2003 Dec 16.

11.

Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.

da Costa Prando E, Cavalli LR, Rainho CA.

Epigenetics. 2011 Dec;6(12):1413-24. doi: 10.4161/epi.6.12.18271.

12.

Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl oxidase and suppressing Smad2/3 signaling.

Nilsson G, Kannius-Janson M.

BMC Cancer. 2016 Feb 23;16:142. doi: 10.1186/s12885-016-2196-2.

13.

PLCD1 is a functional tumor suppressor inducing G(2)/M arrest and frequently methylated in breast cancer.

Xiang T, Li L, Fan Y, Jiang Y, Ying Y, Putti TC, Tao Q, Ren G.

Cancer Biol Ther. 2010 Sep 1;10(5):520-7. doi: 10.4161/cbt.10.5.12726. Epub 2010 Sep 21.

PMID:
20657189
14.

Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer.

Veeck J, Noetzel E, Bektas N, Jost E, Hartmann A, Knüchel R, Dahl E.

Mol Cancer. 2008 Nov 6;7:83. doi: 10.1186/1476-4598-7-83.

15.

Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function.

Markey MP, Bergseid J, Bosco EE, Stengel K, Xu H, Mayhew CN, Schwemberger SJ, Braden WA, Jiang Y, Babcock GF, Jegga AG, Aronow BJ, Reed MF, Wang JY, Knudsen ES.

Oncogene. 2007 Sep 20;26(43):6307-18. Epub 2007 Apr 23.

PMID:
17452985
16.

Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness.

Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T.

Oncogene. 2014 Oct 2;33(40):4837-46. doi: 10.1038/onc.2013.427. Epub 2013 Nov 4.

PMID:
24186199
17.

E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.

Lu Z, Luo RZ, Peng H, Huang M, Nishmoto A, Hunt KK, Helin K, Liao WS, Yu Y.

Oncogene. 2006 Jan 12;25(2):230-9.

PMID:
16158053
18.

Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer.

Yu J, Ma X, Cheung KF, Li X, Tian L, Wang S, Wu CW, Wu WK, He M, Wang M, Ng SS, Sung JJ.

Oncogene. 2010 Dec 9;29(49):6464-74. doi: 10.1038/onc.2010.370. Epub 2010 Aug 30.

PMID:
20802524
19.

Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.

Rodriguez BA, Weng YI, Liu TM, Zuo T, Hsu PY, Lin CH, Cheng AL, Cui H, Yan PS, Huang TH.

Carcinogenesis. 2011 Jun;32(6):812-21. doi: 10.1093/carcin/bgr017. Epub 2011 Feb 8.

20.

Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer.

Liu WB, Han F, Du XH, Jiang X, Li YH, Liu Y, Chen HQ, Ao L, Cui ZH, Cao J, Liu JY.

Int J Cancer. 2014 Mar 15;134(6):1311-22. doi: 10.1002/ijc.28472. Epub 2013 Nov 11.

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